Abstract: A process for the production of HSA in Pichia pastoris cells comprising cultivating Pichia pastoris cells capable of expressing HSA at a pH of about 5.7 to about 6.4 contemporaneously with the expression of HSA.
Type:
Grant
Filed:
April 25, 1991
Date of Patent:
July 19, 1994
Assignee:
Research Corporation Technologies, Inc.
Inventors:
William D. Prevatt, Kotikanyadan Sreekrishna