Patents Examined by J. Turnipseed
  • 1(2H)-isoquinolinones and 1-isoquinolineamines as cancer chemotherapeutic agents
    Patent number: 4942163
    Abstract: 3-(1-Naphthalenyl)-1(2H)-isoquinolinones and 3-(1-naphthalenyl)-1-isoquinolineamines are useful as cancer chemotherapeutic agents.
    Type: Grant
    Filed: March 7, 1989
    Date of Patent: July 17, 1990
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Carl H. Behrens
  • Methyl-piperazino derivatives with analgesic activity
    Patent number: 4562191
    Abstract: New methyl-piperazino derivatives of formula: ##STR1## where R is H or methyl, at least one R being methyl. These products are excellent analgesics with peripheral and central activity, and are free from side effects.
    Type: Grant
    Filed: November 2, 1984
    Date of Patent: December 31, 1985
    Assignee: Euroresearch S.R.L.
    Inventor: Diego Furlan
  • Tricyclic quinazoline derivatives
    Patent number: 4377580
    Abstract: Quinazoline derivatives of the formulae: ##STR1## wherein A.sup.1 is ##STR2## A.sup.2 is ##STR3## R.sup.1 is hydrogen, carboxy or esterified carboxy, R.sub.a.sup.1 and R.sub.b.sup.1 are esterified carboxy,R.sup.2 and R.sup.3 are hydrogen, alkyl, halogen, nitro, amino, alkoxy, aryloxy, alkylthio, alkylpiperazinyl, acylamino or dialkylamino which may be substituted with hydroxy,R.sup.4 is hydrogen, alkyl, hydroxy, alkoxy, alkenyloxy, dialkylamino or 2,2-dialkoxycarbonylvinylaminoR.sub.a.sup.4 is hydrogen, alkyl, hydroxy, alkoxy, alkenyloxy or dialkylamino,R.sup.5 is alkyl or alkenyl, andR.sup.6 is carboxy or esterified carboxy.
    Type: Grant
    Filed: November 25, 1980
    Date of Patent: March 22, 1983
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Ikuo Ueda, Masayuki Kato, Masanobu Nagano
  • Tetrahydroisoquinoline compounds and a pharmaceutical composition thereof
    Patent number: 4294832
    Abstract: A tetrahydroisoquinoline compound of the formula: ##STR1## wherein R.sup.1 is alkyl of one to six carbon atoms, cycloalkyl of three to six carbon atoms, allyl or propargyl, R.sup.2 is hydrogen or alkyl of one to six carbon atoms, and R.sup.3 is hydrogen, alkyl of one to six carbon atoms or benzyl. Methods for preparing the compound (I) are disclosed. The compound (I) and a pharmaceutically acceptable salt thereof are useful as a diagnostic or therapeutic agent for angiotensin-related hypertension.
    Type: Grant
    Filed: April 10, 1980
    Date of Patent: October 13, 1981
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Naoto Yoneda, Jyoji Kato, Keizo Kinashi