Patents Examined by J. Weber
  • Process for the production of 6-hydroxynicotinic acid
    Patent number: 5082777
    Abstract: Process for the production of 6-hydroxynicotinic acid from nicotinic acid. The hydroxylation is carried out enzymatically in the presence of a microorganism of the species Pseudomonas, Bacillus or Achromobacter, for example, Achromobacter xylosoxydans. Preferably the enzymatic hydroxylation is carried out at 20.degree. to 40.degree. C. and a pH of 5.5 to 9.0 under aerobic conditions. Also, preferably a 0.1 percent by weight solution up to a saturated (preferably a 0.5 to 10 percent by weight) nicotine acid solution is used.
    Type: Grant
    Filed: February 14, 1985
    Date of Patent: January 21, 1992
    Assignee: Lonza Ltd.
    Inventors: Pavel Lehky, Hans Kulla, Stephane Mischler