Abstract: The invention relates to an anti-inflammatory factor isolated from milk and to methods for using this factor to remove adhered neutrophils from endothelial cells, to prevent the emigration of cells from the vasculature and to suppress the response of lymphocytes to foreign antigens.
Type:
Grant
Filed:
October 27, 1992
Date of Patent:
October 4, 1994
Assignee:
Stolle Research & Development Corporation
Abstract: The subject invention provides a method of protecting a human from lung injury due to hyperoxia and hyperventilation which comprises intratracheally administering to the human an amount of free CuZnSOD effective to protect the human from lung injury due to hyperoxia and hyperventilation.
Abstract: A method of degrading halogenated aliphatic hydrocarbons is disclosed comprising incubating microorganisms capable of degrading halogenated aliphatic hydrocarbons by an aromatic degradative pathway together with the halogenated aliphatic hydrocarbons under conditions such that said aromatic degradative pathway is active.
Type:
Grant
Filed:
July 9, 1990
Date of Patent:
December 10, 1991
Assignees:
Ecova Corporation, The United States of America as represented by the Administrator of the Environmental Protection Agency
Inventors:
Michael J. K. Nelson, Al Willis J. Bourquin, Parmely H. Pritchard
Abstract: A composition comprising LYCD together with known topically active useful medicinal agents such as antiwrinkling, antibiotic, anticancer, antifungal, antiinflammatory, antiviral, steroid, and wound healing agents. The LYCD works together with the other active ingredients to achieve a synergistic result more effective than can be obtained from the topical agents individually, and more effective than could be predicted from the mere addition of the known efficacies of the individual ingredients.
Abstract: A blood substitute suitable for replacing blood in mammalian subjects when performance of surgical procedures at hypothermic temperatures is described. The blood substitute comprises water, electrolytes at physiological concentration, dextran 40 at a concentration sufficient for the blood substitute to achieve a colloidal suspension having a fluid osmotic pressure essentially equivalent to mammalian plasma, HEPES buffer at a physiological pH, dextrose, magnesium ion at a concentration of about 0.01M and potassium ion at a concentration greater than 10 mEq per liter sufficient to prevent or arrest cardiac fibrillation. In one embodiment the blood substitute is a multi-solution system wherein the solutions comprise differing levels of the above-indicated componants and are administered sequentially to completely replace a subjects circulating blood.
Type:
Grant
Filed:
October 23, 1990
Date of Patent:
September 22, 1992
Assignee:
Cryomedical Sciences, Inc.
Inventors:
Paul E. Segall, Harold D. Waitz, Hal Sternberg