Abstract: The invention concerns a composition of fragments of DNA utilizable as a probe for the detection of specific micoorganism, notably Legionella, in environments which contain them. These compositions are obtained from the whole genomes of the microorganisms to be detected, after fragmentation of these genomes, particularly by using a restriction enzyme, and eliminating those sequences of the genomic DNA which are susceptible to being transcribed to ribosomal RNA.
Type:
Grant
Filed:
August 2, 1985
Date of Patent:
March 7, 1989
Assignees:
Institut Pasteur, Institut National de la Sante et de la Recherche Medicale
Inventors:
Paul Tchen, Nicole Desplaces, Patrick Grimont, Francine (maiden name Besse) Grimont