Abstract: In some examples, a delivery device includes a handle that includes a control member, an elongate body, a plurality of arms extending from a distal portion of the elongate body to a distal collar configured to releasably couple to an annuloplasty device. The plurality of arms is operatively coupled to the control member and configured to position the annuloplasty device at a target site in a patient. The delivery device further comprises a plurality of anchors configured to secure the annuloplasty device to tissue at the target site, each respective anchor of the plurality of anchors deployable from a respective arm of the plurality of arms.

Abstract: Tools, assemblies, devices, systems, and methods for easily mounting a crown to a titanium (Ti) base or custom abutment with a tool without having to pre-cement a mounting base to a crown and have to physically hold together the base to the crown until the cement is cured. The implant cementation assembly tool does allow the Ti base and crown to be cemented (pre-cemented) without being constantly held and done outside of the mouth. The embodiments can include a bottom (hard rod, such as plastic or metal) that goes through the Ti base and the crown. The embodiments can include a top that is either threaded to allow it to be screwed onto the hard rod or a top that has a hollow center that can slide over the hard rod and be clamped to the rod. A second embodiment uses a modified hemostat tool with lockable pivoting arms to clamp the crown to the Ti base to allow cement to become set.

Abstract: A high performance, low-cost passive prosthetic knee includes one or more modules to enable able-bodied gait by transfemoral amputees to improve metabolic efficiency and reduce stigma from conspicuous abnormal gaits. A stance stability module includes a latch with a virtual lock axis that automatically locks and unlocks. An early stance flexion module enables able-bodied gait during stance. Hydraulic fluid dampers ensure reliable swing phase control. A swing extension energy storage module stores and returns energy as the knee locks and unlocks, respectively. These modules may be used together, in any combination, or individually.

Abstract: A system can be used to record real-time pressure and/or shear force data within a socket for a prosthetic device. The system includes a socket for a prosthetic device that can be designed to fit a patient's residual limb. The system also includes a sensor array that can be placed within the socket for the prosthetic device to detect pressure and/or shear force on the patient's residual limb. The sensor array includes a piezo-electric material and a uniform distribution of a plurality of metal pads on either side of the piezo-electric material. Each of the plurality of metal pads on either side of the piezo-electric material comprises at least one wire connected to a common port.

Abstract: An adjustable length medical device, such as a drainage stent, and delivery device for placing within the body, having an elongate tube and retention members at each end portion for anchoring the device in the body. The proximal portion of the device including the proximal retention member may be segmented in incremental portions so that the length of the device can be adjusted for placement.

Abstract: Devices, systems and methods are provided for stabilizing and grasping tissues such as valve leaflets, assessing the grasp of these tissues, approximating and fixating the tissues, and assessing the fixation of the tissues to treat cardiac valve regurgitation, particularly mitral valve regurgitation.

Abstract: A prosthetic knee includes a hydraulic resistance system with an extension hydraulic circuit and a flexion hydraulic circuit. The flexion hydraulic circuit includes a switchable resistance assembly with a mechanical switch. The mechanical switch has an engaged position and a released position. The switchable resistance assembly provides a first level of hydraulic resistance when the mechanical switch is in the released position and a second level of hydraulic resistance when the mechanical switch is in the engaged position, the second level being less than the first level. The mechanical switch moves to the engaged position when the hydraulic resistance element reaches a predetermined extension position and moves back to the released position when fluid flow falls below a predetermined threshold.

Abstract: An apparatus is provided that stabilizes an applicator in response to the motion caused by a user, comprising: a receiver configured to be coupled with a cosmetic applicator; at least one sensor configured to detect a movement caused by a user; circuitry configured to determine a compensation movement to offset the detected movement; and at least one motion generation device embedded in the receiver configured to control a motion of the cosmetic applicator according to the determined compensation movement.

Abstract: A monolateral actuation system of a hip articulation is configured to be connected to an orthosis. The monolateral actuation system comprises a motor device arranged to provide assistive torque at a motor axis; a transmission device is connected to the motor axis and arranged for transferring the assistive torque onto an output axis corresponding to an axis of flexion-extension of the hip articulation and parallel to the motor axis. The transmission device includes a cable and first and second pulleys connected to one another by the cable. The first and second pulleys are arranged to extend relative to one another variably. A fixed frame is provided for connecting to the orthosis onto which the motor device and the transmission device are mounted.

Abstract: A prosthetic ankle has an ankle joint body (10A) constituting a shin component and a foot component (12). The ankle joint body (10A) is pivotally connected to the foot component (12) by a first pivotal connection (14) defining a medial-lateral ankle joint flexion axis. The ankle joint body (10A) also forms the cylinder of an ankle joint piston and cylinder assembly with a superior-inferior central axis, the cylinder housing a piston (16) with upper and lower piston rods (16A, 16B). The lower piston rod (16B) is pivotally connected to the foot component (12) at a second pivotal connection (18). As the ankle joint body (10A) pivots about the ankle joint flexion axis, the piston (16) moves substantially linearly in the cylinder formed by the ankle joint body. The cylinder is divided into upper and lower chambers (20A, 20B).

Abstract: A prosthetic heart valve includes a collapsible and expandable stent and a plurality of commissure features disposed on the stent. A collapsible and expandable valve assembly includes a plurality of leaflets connected to the plurality of commissure features, each commissure feature including a body having a proximal end and a distal end. A plurality of eyelets is arranged in rows and columns on the body for distributing load from the plurality of leaflets.

Abstract: A prosthetic leg knee joint includes a thigh connection part that is provided on the thigh side, a lower leg part that is provided rotatably around a knee shaft connected to the thigh connection part, a four-bar link mechanism that sets an instant center S whose relative position with respect to the thigh connection part is substantially constant regardless of the relative position between the thigh connection part and the lower leg part, and a braking unit that brakes the movement of the lower leg part in accordance with the relative position between the instance center S set by the four-bar link mechanism and the lower leg part.

Abstract: Support frames and medical devices are described. An example medical device comprises an expandable support frame with first and second leaflets attached to the support frame. Each of the first and second leaflets defines a domed radius that is equal to or less than the radius of the expandable support frame when the expandable support frame is in an expanded configuration and the leaflets are subjected to fluid pressure sufficient to affect closure of the valve orifice.

Abstract: A prosthetic heart valve includes a collapsible stent and a valve assembly disposed within the stent. A first cuff is disposed adjacent the stent. A filler is annularly disposed about the stent radially outward of the first cuff and radially outward of the stent. The filler has a first circumferential layer with a first inner wall, a first outer wall, and a plurality of first ribs connecting the first inner wall to the first outer wall. The filler has an expanded condition in which the first inner wall is spaced a first distance from the first outer wall in a radial direction transverse to the longitudinal direction of the stent, and a collapsed condition in which the first inner wall is spaced a second distance from the first outer wall in the radial direction, the first distance being greater than the second distance.

Abstract: A stent includes a high radial force segment and a highly flexible segment, where the diameters of the high radial force segment and the highly flexible segment are different. For example, the stent may be formed from a tube having varying diameters as it extends distally combined with increased strut density to achieve increased flexibility distally while reducing loss of radial stiffness. The stent may further be placed with an additional stent segment, where the additional stent segment has a radial force similar to the radial force of the highly flexible force segment.

Abstract: An apparatus for protecting heart tissue from an implanted inlet element of a blood pump. The apparatus includes a flange member having a first radially constricted configuration and a second radially expanded configuration, the flange member being biased in its second radially expanded configuration. The flange member defines an opening there through sized to receiving the inlet element of the blood pump. A retaining element extending from the flange member is included, the retaining element being flexible and sized to be disposed about at least a portion of the inlet element.

Abstract: A method for implanting a replacement heart valve within a diseased valve includes accessing a patient's heart by piercing a myocardium, advancing a guidewire into the patient's heart, and installing an access device in a wall of the heart. The access device preferably has at least one valve mechanism. A valve delivery device is advanced over the guidewire and through the access device. The valve delivery device has a replacement heart valve disposed along a distal end portion thereof. The replacement heart valve preferably includes an outer support structure and a leaflet valve disposed within the outer support structure. The replacement heart valve is radially expanded within the diseased valve. During implantation, the outer support structure conforms to a diameter of the diseased valve and the leaflet valve expands to a fixed size having a diameter smaller than the diameter of the diseased valve.

Abstract: Devices, systems and methods are provided for stabilizing and grasping tissues such as valve leaflets, assessing the grasp of these tissues, approximating and fixating the tissues, and assessing the fixation of the tissues to treat cardiac valve regurgitation, particularly mitral valve regurgitation.

Abstract: The invention relates to a heart valve regurgitation drum and optional closure disk and/or tubular stent to manage and provide levels of intentional regurgitation within an orthogonally delivered transcatheter prosthetic heart valve having a first inner flow control component/valve, a second inner regurgitation control component, and an outer annular support frame having compressible wire cells that facilitate folding flat along the z-axis and compressing the valve vertically along the y-axis, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

Abstract: A cranial implant for access to a cerebral cortex includes a window member shaped and dimensioned for positioning within a dural defect to provide access through the dura such that access to the cerebral cortex is provided in a location under study. An implant body is provided having a geometry that substantially conforms to a resected portion of a patient's anatomy to which the implant body is to be secured.