Abstract: A method for calculating quantitative perfusion measurements using an MRI system includes a pulse sequence that acquires perfusion weighted images and additionally measures T1 values before and after the administration of a contrast agent. T1 values are measured by rapidly sampling a longitudinal relaxation curve and employed to determine the blood volume in tissue. A correction factor for the effect of water diffusion between blood vessels and the extravascular space is determined.
Type:
Grant
Filed:
November 16, 2007
Date of Patent:
January 17, 2012
Assignee:
Northwestern University
Inventors:
Timothy J. Carroll, Wanyong Shin, Jessy J. Mouannes