Patents Examined by James C. Jousel
  • (.fwdarw.)-.beta.- d-glucan binding protein, an antibody recognizing the protein and use thereof
    Patent number: 6156519
    Abstract: A (1.fwdarw.3)-.beta.-D-glucan binding protein obtainable by affinity chromatography or gel filtration of an extract of horseshoe crab amoebocytes and having a molecular weight of about 580 kDa, as determined by gel filtration under non-reducing conditions, and about 170 kDa, as determined by SDS-PAGE under reducing conditions, is provided.An antibody which selectively recognizes the protein is also provided. Methods for detecting or removing (1.fwdarw.3)-.beta.-D-glucan in or from a sample using the protein and antibody are disclosed.
    Type: Grant
    Filed: June 2, 1997
    Date of Patent: December 5, 2000
    Assignee: Seikagaku Corporation
    Inventors: Hiroshi Tamura, Shigenori Tanaka