Abstract: Devices, systems and methods for the treatment of chronic inflammatory disorders that include an implantable microstimulator and an external charger/controller wherein the microstimulator is configured to operate using closed-loop feedback. The feedback for the microstimulator can be electrical activity of the vagus nerve and/or heart sensed by the microstimulator. The feedback can be used to modulate the stimulation duration, intensity, frequency, on-time and off-time.

Abstract: Embodiments generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for lenticular laser incisions to form a top lenticular incision, a bottom lenticular incision of a lens in the subject's eye, an added shape between the top and bottom incisions where the added shape has no corrective power and a transition ring bisecting both the top and bottom lenticular incisions.

Abstract: Embodiments in accordance with the present disclosure are directed to methods and apparatuses used for slow wave activity (SWA) optimization. An example method includes receiving one or more bio-signals from a user and classifying sleep stages by processing the bio-signals. The method further include determining dominant peripheral nervous system (PNS) oscillations based on the bio-signals and as a function of time and stage of sleep, and characterizing at least one property of the dominant PNS oscillations, including a phase, a phase shift, an amplitude, and/or frequency. The method further include providing an indication of an optimal window for maximizing SWA generation based on the phase, the phase shift, the amplitude, or the frequency. The indication is provided to stimulation circuitry that delivers stimulation to the user within the optimal window. Feedback is provided responsive to the stimulation based on an EEG signal of the user.

Abstract: Provided are a system and a computer program for managing and predicting thyrotoxicosis using a wearable device. The system for predicting thyrotoxicosis is a system for predicting thyrotoxicosis using a resting heart rate, the system including a wearable device for measuring the heart rate of a patient at regular intervals, and a bio-signal computing device for receiving heart rate information from the wearable device, the bio-signal computing device outputting a warning alarm when a resting heart rate is greater than a reference heart rate when the patient is in a normal state.

Abstract: A wearable device includes an external light collector configured to collect external light; a sensor including an auxiliary light source and a light receiver, and configured to measure a bio-signal of an object; and a processor configured to determine whether the external light is sufficient to measure the bio-signal, and to control driving of the auxiliary light source based on the determination.

Abstract: A therapeutic illumination assembly includes a catheter and a point source treatment fiber. The catheter comprises a catheter wall encircling a luminal fluid pathway. The point source treatment fiber is positioned within the luminal fluid pathway of the catheter. Further, the point source treatment fiber comprises a plurality of light emitting point sources intermittently positioned along a treatment length of the point source treatment fiber such that the plurality of light emitting point sources irradiate the catheter when the plurality of light emitting point sources emit light.

Abstract: A method and an apparatus for switching an ECG measurement mode, a wearable device, and a computer-readable storage medium. The method includes: receiving two successive pieces of PPG data transmitted by an optical heart-rate sensor, where the PPG data is generated by a contact between a measurement electrode and a skin; calculating a difference between the two received pieces of the PPG data; and controlling switching among measurement modes based on the difference, where the measurement modes comprise an ECG wristband mode and an ECG chest-lead mode Manual switching of an ECG measurement mode is avoided with simple operations, high efficiency, and more intelligence.

Abstract: A multi-functional health monitoring mat which enables the measurement of—but not limited to the following parameters: Weight, Plantar pressure, Bio-impedance for body composition, and Cardiovascular based measurements, such as: Electrocardiogram (ECG), Ballistocardiogram (BCG) from which additional health indicating analytics can be further extracted. The mat will be comprised of 3 separate layers: (1) A Bottom Layer, used for weight measurement, comprising force measurement sensors (2) A Middle Layer, used for pressure measurement, comprising pressure sensors in a matrix, and (3) A Top Layer, used for bio-impedance measurement, comprising conductive sensors, distributed throughout the top layer, enabling random orientation of the feet. In addition, there will be an electronic sub-system to enable communication of data and information from the bath mat to a mobile application.

Abstract: An implantable medical device includes an activity sensor, a pulse generator, and a control module. The control module is configured to determine activity metrics from the activity signal and determine an activity metric value at a predetermined percentile of the activity metrics. The control module sets a lower pacing rate set point based on the activity metric value at the predetermined percentile.

Abstract: A method, comprising receiving a time series of patient body signal, determining first and second sliding time windows for the time series; applying an autoregression algorithm, comprising: applying an autoregression analysis to each of the first and second windows, yielding autoregression coefficients and a residual variance for each window; estimating a parameter vector for each window based on the autoregression coefficients and residual variances; and determining a difference between the parameter vectors; and determining seizure onset and seizure termination based on the difference between the parameter vectors. A non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform the method.

Abstract: A sinus treatment device and methods of operating the sinus treatment device that include an enhanced conductive tip and at least one return electrode are disclosed.

Abstract: An example multi-fiber, multi-spot laser probe comprises a plurality of fibers extending from a proximal end of the laser probe to at least near a distal end of the laser probe, where the proximal end of the laser probe is configured to be coupled to a laser source via an adapter interface, and a cannula having a distal end and surrounding the plurality of fibers along at least a portion of the laser probe at or near the distal end of the laser probe, where a distal end of each of the plurality of fibers is angle-polished so that the distal end of each fiber is angled relative to a longitudinal axis of the cannula and relative to a plane perpendicular to the longitudinal axis of the cannula. Additional embodiments employ lensed fibers, a distal window, ball lens, lens array, or faceted wedge.

Abstract: Provided are a system and a computer program for managing and predicting thyrotoxicosis using a wearable device. The system for predicting thyrotoxicosis is a system for predicting thyrotoxicosis using a resting heart rate, the system including a wearable device for measuring the heart rate of a patient at regular intervals, and a bio-signal computing device for receiving heart rate information from the wearable device, the bio-signal computing device outputting a warning alarm when a resting heart rate is greater than a reference heart rate when the patient is in a normal state.

Abstract: Systems, methods, and devices are described herein for evaluation, adjustment, and delivery of adaptive cardiac therapy. The systems, methods, and devices may utilize electrical heterogeneity information to determine and/or select one or more pacing settings and pacing type or configurations for a plurality of different heart rates. The adaptive cardiac therapy may deliver cardiac therapy at selected pacing settings such as, for example, A-V and/or V-V intervals, according to a presently measured heart rate and switch between left ventricular-only or biventricular cardiac pacing therapy also according to the presently measured heart rate.

Abstract: A system for detecting an anomalous event in a person includes a body in contact with a skin surface of a person; a heat source for heating the skin surface to a target temperature; a skin temperature sensor for measuring a temperature of the skin surface in contact with the heat source; a blood volume sensor for measuring a blood volume of the skin surface; and a hardware processor communicatively coupled to the heat source, the blood volume sensor, the skin temperature sensor, and an environmental temperature sensor. The hardware processor is configured to receive a baseline blood volume signal, output a heating signal to the heat source to initiate a heating cycle, receive a second blood volume signal from the blood volume sensor, compare the second blood volume signal to the baseline blood volume signal, and determine whether an anomalous biologic event has occurred.

Abstract: An example system for monitoring and delivering therapy to a patient includes a monitor module with patient monitoring capability, and a manifold that is operable to provide an electrical connection between the monitor module and cables connecting to sensors for collecting physiologic monitoring data of a patient, and to provide a gas connection between the monitor module and tubing for delivering treatment to or collecting additional physiologic monitoring data from the patient. The manifold includes a connector for mechanically connecting the manifold to the monitor module, and the connector also for mechanically disconnecting the manifold from the monitor module while maintaining the cables and the tubing coupled to the patient. In some examples, the system can also include a cot including a second set of monitoring electronics with patient monitoring capability, the cot including a port for coupling with the connector of the manifold.

Abstract: A mobile electrocardiogram (ECG) device is described, comprising an electrode assembly comprising electrodes, wherein the electrode assembly senses heart-related signals when in contact with a body of a user, and produces electrical signals representing the sensed heart-related signals. The mobile ECG device further comprises a converter assembly electrically connected to the electrode assembly, configured to convert the electrical signals to a modulated signal, wherein the modulated signal carries the electrical signals representing the sensed heart-related signals. The mobile ECG device further comprises a transmitter that transmits the modulated signal wirelessly to a computing device. The mobile ECG device further comprises a light-emitting device to facilitate an optimal placement of the electrode on the body of the user. The mobile ECG device further comprises a housing containing the electrode assembly, the converter assembly, the transmitter, and the light-emitting device.

Abstract: A vaginal device configured to be inserted in a vagina of a user, the vaginal device comprising: a body comprising at least two electrodes configured to measure a fertility-related parameter of the user; a power source configured to provide power to the device; and an electrical system operably connected to the power source, the electrical system operably connected to one or more of the electrodes, the electrical system configured to switch one or more of the electrodes between charging and measuring functions.

Abstract: This system is a network of sensor nodes with multiple sensors at each node. The nodes are used in combination with a wearable garment to enable multiple types of data to be combined together to produce a fuller picture of a body's physiological state; such as during physical therapy. In addition, the system utilizes acoustic imaging to measure muscle activation. The system transmit this data to a host computer to visualize various data comparisons.

Abstract: User interface for external power source, recharger, for an implantable medical device. At least some of patient controls and display icons of an energy transfer unit are common with at least some of the patient controls and the display icons of a patient control unit. An energy transfer unit is operable by the patient with less than three operative controls to control energy transfer from the external energy transfer unit to the implantable medical device. An external antenna having a primary coil can inductively transfer energy to a secondary coil of the implantable medical device when the external antenna is externally placed in proximity of the secondary coil. An energy transfer unit has an external telemetry coil allowing the energy transfer unit to communicate with the implantable medical device through the internal telemetry coil in order to at least partially control the therapeutic output of the implantable medical device.