Patents Examined by James Q. Warren
  • Optimized formulation of tobramycin for aerosolization
    Patent number: 6987094
    Abstract: The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room temperature. Said formulation can be advantageously used for the treatment and prophylaxis of acute and chronic endobronchial infections, in particular those caused by the bacterium Pseudomonas aeruginosa associated to lung diseases such as cystic fibrosis.
    Type: Grant
    Filed: June 14, 2002
    Date of Patent: January 17, 2006
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Chiara Malvolti, Raffaella Garzia