Patents Examined by Jameson Ma
  • Patent number: 8058060
    Abstract: The present invention relates to a culture insert carrier, a culture insert and a culture system for culturing and testing of different kinds of cells, such as for example skin models. A culture insert carrier for supporting at least one culture insert in a culture tray having at least one well, wherein the culture insert carrier comprises a plane member with at least one opening for insertion of the at least one culture insert in such a way that the culture insert carrier supports the at least one culture insert in a position in the culture tray is provided. Further, a culture insert comprising a plurality of suspension elements including a first set of suspension elements and a second set of suspension elements, the suspension elements being adapted to suspend the culture insert in a plurality of vertical positions, including a first vertical position and a second vertical position, in relation to a frame is provided.
    Type: Grant
    Filed: June 9, 2006
    Date of Patent: November 15, 2011
    Assignee: Nunc A/S
    Inventors: Peter Esser, Frank T. Stigborg, Klaus Pedersen, Stefan Iskov
  • Patent number: 8030058
    Abstract: Advanced islet separation technology incorporates an automated method, automated control methodology, process control interface, and automated apparatus to separate (isolate) and process pancreatic islets in a tissue suspension in physiologic process solution, utilizing microprocessor control and/or microprocessor computer control and software programming (code) to interface and control the process temperature, fluid flow rate, pH, dissolved oxygen concentration, endotoxin concentration, dissolved nitric oxide concentration, nitric oxide synthase activity, proteolytic enzyme activity, and/or pressure of the islet containing physiologic process solution, the extent of islet separation, including real-time data acquisition and recording of process variables.
    Type: Grant
    Filed: March 3, 2006
    Date of Patent: October 4, 2011
    Inventors: Daniel J. Benedict, Lorna S. Mosse
  • Patent number: 8017384
    Abstract: A modular membrane supported bioreactor for anaerobic conversion of gas into liquid products including membrane module(s) having a plurality of hollow fibers packed across a cross sectional area of the membrane module in a direction transverse to the axis of the membrane module; a membrane vessel for retaining the membrane module(s) at least partially submerged in a process liquid and isolated from ambient atmosphere; and a gas supply conduit operably connected to the hollow fibers for supplying a process gas to the hollow fiber lumens. The gas supply conduit enables the formation of a biofilm on the outer surface of the hollow fiber wall by interaction of microorganisms with the process gas and the production of a liquid product that mixes with the process liquid.
    Type: Grant
    Filed: April 29, 2008
    Date of Patent: September 13, 2011
    Assignee: Caliper Life Sciences, Inc.
    Inventors: Shih-Perng Tsai, Rathin Datta, Rahul Basu, Seong-Hoon Yoon, Richard E. Tobey