Patents Examined by Jameson Q Ma
  • Patent number: 8017091
    Abstract: A device consisting of a low-RPM motor wherein the motor spins a flat disk, a peg is attached to the disk, a stationary spring armature wherein the peg can activate the stationary spring armature as the disk rotates, and a tube containing beads in a fluid positioned in a top plate wherein the spring armature can contact the tube. This device can further include a soft closed-cell foam top mounted on the top plate wherein the tube is inserted and maintained by the foam in such a way as to allow for slight motion of the tube induced by the contact by the spring armature.
    Type: Grant
    Filed: November 20, 2006
    Date of Patent: September 13, 2011
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Turan A. Kayagil, Julie A. Richardson
  • Patent number: 8007744
    Abstract: The present invention relates to a sample container for analyses suitable for medical diagnostics comprising a platform plate having at least one reaction chamber. The reaction chamber has a bottom and a sidewall which form a three-dimensional chamber which is open in the upward direction. The ratio of the numerical value of the surface area of the bottom is relatively large relative to the height of the sidewall. The ratio may be greater than or equal to 30, 35, 40, 45, 50, 60, 70, 80, or 90. The reaction chamber further comprises a binding area on an internal surface of the reaction chamber which may be functionalized for binding at least one chemical entity for use in an assay.
    Type: Grant
    Filed: January 16, 2004
    Date of Patent: August 30, 2011
    Assignee: Greiner Bio-One GmbH
    Inventors: Günther Knebel, Jörg Stappert, Heinrich Jehle, Joachim Kessler
  • Patent number: 7981668
    Abstract: A method and system for culturing cells, having a substantially airtight enclosure configured to culture cells. The method and system also have a first conduit configured to provide a reduced pressure to the substantially airtight enclosure and a second conduit configured to provide a culture media to the substantially airtight enclosure.
    Type: Grant
    Filed: January 17, 2007
    Date of Patent: July 19, 2011
    Assignee: KCI Licensing Inc.
    Inventors: Robert P. Wilkes, Amy K. McNulty, Kristine Kieswetter, Teri D. Feeley, Marisa Schmidt
  • Patent number: 7981686
    Abstract: A method of assessing body odor using as an index an indicator material comprising an alcohol compound having a mercapto group at the 3-position represented by the following formula (2) and/or a substance that is a derivative of an alcohol compound having a mercapto group at the 3-position, wherein an atom(s) or an atom group(s) is introduced to a mercapto group and/or a hydroxyl group of an alcohol compound having a mercapto group at the 3-position represented by the formula (2):
    Type: Grant
    Filed: March 30, 2010
    Date of Patent: July 19, 2011
    Assignee: Kao Corporation
    Inventors: Masayuki Yabuki, Yoshihiro Hasegawa, Masamoto Matsukane
  • Patent number: 7972839
    Abstract: The device and method invented provides a unique means to extract and multiply, by the millions, beneficial aerobic microbes found in compost and vermicompost to be applied to soil and plants in liquid form. Compared to many compost tea making devices being sold, the invented device is truly simple and can be dismantled and cleaned in under twenty minutes. Most of the parts are not glued and can be pulled apart. The device and method uses air pumps alone to actually circulate the water and can be used with or without a mesh extractor. This is achieved by the insertion of an air diffuser into the piping used, which infuses the water with oxygen while circulating the water, into either, an extractor containing compost or a body of water containing compost. Concurrently additional diffusers infuse the body of water with oxygen.
    Type: Grant
    Filed: January 19, 2009
    Date of Patent: July 5, 2011
    Inventor: Timothy James Wilson
  • Patent number: 7972841
    Abstract: The present invention relates to an exposure device for living cell cultures, the device having a medium chamber common to a plurality of cell culture chambers and medium directing means. The medium chamber, cell culture chambers and the medium directing means may be arranged so as to provide substantially contemporaneous medium exchange at the cell culture chambers.
    Type: Grant
    Filed: May 22, 2003
    Date of Patent: July 5, 2011
    Assignee: British American Tobacco (Investments) Limited
    Inventors: Elan David Massey, Justine Williamson, Jeremy Francis Neale Phillips
  • Patent number: 7926681
    Abstract: An apparatus for storing and dispensing a test strip includes a container configured to store a radial array of test strips. The container maintains appropriate environmental conditions, such as humidity, for storing the test strips. The container has a plurality of radially extending slots formed by a plurality of dividing walls, and each slot is sized to receive a single test strip. A rotatably positionable cover is carried by the container for covering the plurality of radially extending slots. The cover includes an opening, which, when the cover rotates, aligns with one of the slots at a time to allow removal of a single test strip located within the respective slot. Accordingly, the unused test strips remain free of contaminants such as naturally occurring skin oils on a user's hand.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: April 19, 2011
    Assignee: Becton, Dickinson and Company
    Inventors: Robert E. West, John Lovell
  • Patent number: 7923227
    Abstract: A stable system for producing liquid products such as ethanol, butanol and other chemicals from syngas components contacts CO or a mixture of CO2 and H2 with a hydrophilic membrane under anaerobic conditions and transfers these components into contact with microorganisms contained as a biofilm on the membrane. Maintaining the microorganisms as a biolayer on the surface of the membrane facilitates cleaning of the membrane surface that retains the biofilm. In addition the shell gas space that surrounds the membranes may be flooded to reduce or remove the biofilm. Agitation of the liquid, by for example the bubbling of gas in the surrounding shell space, can fully or partially remove the biofilm from the membrane.
    Type: Grant
    Filed: October 6, 2009
    Date of Patent: April 12, 2011
    Assignee: Coskata, Inc.
    Inventors: Robert Hickey, Rahul Basu, Rathin Datta, Shih-Perng Tsai
  • Patent number: 7892820
    Abstract: A cylindrical composting drum which is 6?, 8?, or 10? in diameter, extends between 40? and 140? in length. The drum is rotated and internal helical blades move the material from inlet end to a screen separator at an outlet end. Partially arcuate solar reflectors underlie the drums and reflect solar energy onto the outer surface of the drums which have been blackened to enhance energy absorption. The use of the available solar energy accelerates the composting process. A microprocessor controls the addition of moisture and the timing and rate of rotation of the drums.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: February 22, 2011
    Inventor: John A Bartone, Sr.
  • Patent number: 7892839
    Abstract: In order to check the hermeticity of a closed cavity of at least one micrometric component, said component includes a structure made over or in one portion of a substrate, a cap fixed to one zone of the substrate to protect the structure, and an indicator element whose optical or electrical properties change in the presence of a reactive fluid. The indicator element may be a copper layer for an optical check or a palladium resistor for an electrical check. The micrometric component is placed in a container which is then hermetically closed. This container is filled with a reactive fluid under pressure, which is oxygen for the optical check and hydrogen for the electrical check. The component in the container is subjected to a reactive fluid pressure higher than 10 bars for a determined time period, and to thermal (T>100° C.) or optical (?<500 nm) activation. After this time period, an optical or electrical check of the indicator element determines the hermeticity of said cavity.
    Type: Grant
    Filed: August 18, 2009
    Date of Patent: February 22, 2011
    Assignee: Asulab S.A.
    Inventors: François Gueissaz, Jean-Paul Randin
  • Patent number: 7887757
    Abstract: An apparatus for storing and dispensing a test strip includes a container configured to store a stack of test strips. The container maintains appropriate environmental conditions, such as humidity, for storing the test strips. An engaging member is disposed in the container and is adapted to contact one test strip of the stack of test strips. An actuator actuates the engaging member to dispense the one test strip from the container. Since one test strip is dispensed at a time, the remaining test strips are not handled by the user. Accordingly, the unused test strips remain free of contaminants such as naturally occurring oils on the user's hand.
    Type: Grant
    Filed: May 9, 2006
    Date of Patent: February 15, 2011
    Assignee: Becton, Dickinson and Company
    Inventor: Victor Chan
  • Patent number: 7875447
    Abstract: To provide an inexpensive cell incubator for a single cell operation supporting robot having the markers (first and second feature points) required to transform the position of a cell detected on a table coordinate system into a position on the intrinsic coordinate system of the cell incubator. First and second feature points are formed on a film-like feature point setup chip which is then stuck to the cell incubator body such as a conventional dish, thus constituting a cell incubator. Since manufacture of a new die for forming the first and second feature points directly on the cell incubator body is not required, an inexpensive cell incubator for a single cell operation supporting robot can be provided.
    Type: Grant
    Filed: August 2, 2005
    Date of Patent: January 25, 2011
    Assignees: Chuo Precision Industrial Co., Ltd., Tokyo University of Agriculture and Technology National University Corporation
    Inventors: Yohei Yamada, Mikako Saito, Hideaki Matsuoka
  • Patent number: 7838299
    Abstract: The invention relates to compounds, to the complexes they form with a lanthanide, and to the use of the complexes for fluorescence marking or NMR imaging. The complex consists of an Ln ion and a ligand R2—C(X—R1)(R3)—NR4R5. R1 is a functional group, X is a single bond or a hydrocarbon-based chain consisting of at least one alkylene or alkenylene group optionally comprising at least one hetero atom or an arylene. R2 is an anionic group A2 or a C1-C4 alkylene or alkenylene group bearing at least one such group A2 and optionally comprising at least one hetero atom. R3 is H or a C1-C5 alkylene or alkenylene group optionally containing at least one hetero atom, and optionally bearing at least one anionic group A3. R4 is a substituent with light-absorbing properties that forms chelate rings with Ln. R5 is a substituent that forms chelate rings with Ln.
    Type: Grant
    Filed: February 26, 2010
    Date of Patent: November 23, 2010
    Assignees: Centre National de la Recherche Scientifique, Universite Louis Pasteur de Strasbourg
    Inventors: Loïc Charbonniere, Raymond Ziessel, Nicolas Weibel, Aldo Roda, Massimo Guardigli
  • Patent number: 7833484
    Abstract: In order to check the hermeticity of a closed cavity of at least one micrometric component, said component includes a structure made over or in one portion of a substrate, a cap fixed to one zone of the substrate to protect the structure, and an indicator element whose optical or electrical properties change in the presence of a reactive fluid. The indicator element may be a copper layer for an optical check or a palladium resistor for an electrical check. The micrometric component is placed in a container which is then hermetically closed. This container is filled with a reactive fluid under pressure, which is oxygen for the optical check and hydrogen for the electrical check. The component in the container is subjected to a reactive fluid pressure higher than 10 bars for a determined time period, and to thermal (T>100° C.) or optical (?<500 nm) activation. After this time period, an optical or electrical check of the indicator element determines the hermeticity of said cavity.
    Type: Grant
    Filed: August 18, 2009
    Date of Patent: November 16, 2010
    Assignee: Asulab S.A.
    Inventors: François Gueissaz, Jean-Paul Randin
  • Patent number: 7749749
    Abstract: The present invention relates to a bioreactor for generating uniform distribution of shear stress, comprising: a cone, having a cone surface with an outline of modified catenary; a container, having a fixed plate at the bottom inside the accommodating space of said container, and said fixed plate comprises a plurality of reservoirs; wherein the cone tip located above the center of said fixed plate is capable of loading culture media into the accommodating space of said container, that is, into the space between the cone surface and the fixed plate. More uniform shear stress can be generated in the culture media to act on the sample in the reservoirs of the fixed plate when the cone rotates and makes the culture media run. The bioreactor of the present invention can be applied to generate uniform shear stress acting on the fixed plate despite the distance between the cone tip and the fixed plate.
    Type: Grant
    Filed: April 25, 2007
    Date of Patent: July 6, 2010
    Assignee: National Defense University, Chung-Cheng Institute of Technology
    Inventors: Ta-Wei Ting, Yu-Lun Chen
  • Patent number: 7722818
    Abstract: Apparatus and method capable of preparing samples adapted for observations by electron microscopy. Each sample is ion-etched. During this process, the sample stage is tilted reciprocably left and right about a tilting axis. The sample is ion-etched together with a shielding material. The sample may contain a substance that is not easily etched by the ion beam. In the present invention, such unetched portions are not produced in spite of the presence of the substance. The substance can be separated from the sample. The ion beam is directed at the sample with the boundary defined by an end surface of the shielding material. Portions of the sample at a processing position and its vicinities are etched by the beam.
    Type: Grant
    Filed: September 16, 2004
    Date of Patent: May 25, 2010
    Assignees: JEOL Ltd., JEOL Engineering Co., Ltd.
    Inventors: Fuminori Hasegawa, Tadanori Yoshioka
  • Patent number: 7709263
    Abstract: The invention relates to compounds, to the complexes they form with a lanthanide, and to the use of the complexes for fluorescence marking or NMR imaging. The complex consists of an Ln ion and a ligand R2—C(X—R1)(R3)—NR4R5. R1 is a functional group, X is a single bond or a hydrocarbon-based chain consisting of at least one alkylene or alkenylene group optionally comprising at least one hetero atom or an arylene. R2 is an anionic group A2 or a C1-C4 alkylene or alkenylene group bearing at least one such group A2 and optionally comprising at least one hetero atom. R3 is H or a C1-C5 alkylene or alkenylene group optionally containing at least one hetero atom, and optionally bearing at least one anionic group A3. R4 is a substituent with light-absorbing properties that forms chelate rings with Ln. R5 is a substituent that forms chelate rings with Ln.
    Type: Grant
    Filed: July 20, 2004
    Date of Patent: May 4, 2010
    Assignees: Centre National de la Recherche Scientifique, Universite Louis Pasteur de Strasbourg
    Inventors: Loïc Charbonniere, Raymond Ziessel, Nicolas Weibel, Aldo Roda, Massimo Guardigli
  • Patent number: 7662611
    Abstract: A fixture and method is provided for in vitro storage of a cornea. The fixture includes a platform having a corneal-sceral rim receiving surface, a clamp having a mating surface for the cornel-scleral rim and handles. A locking mechanism is provided to secure a donor cornea between the clamp and platform. The combination cornea, platform and clamp are placed in a storage unit having a fluid preservation media. In one embodiment, the storage unit includes a vial having an optically clear closed end and an opened end. A lid is secured to the open end of the vial and engages the handles in order to stabilize the clamped cornea within the vial.
    Type: Grant
    Filed: October 26, 2005
    Date of Patent: February 16, 2010
    Assignee: Cleo Cosmetic and Pharmaceutical Company, LLC
    Inventors: Rolf A. Schmidt, David B. Soll, Richard C. Pauley
  • Patent number: 7622078
    Abstract: The apparatus comprises an assembly of modules functionally interrelated with one another, and controlled by means of a central control unit in an embodiment of circular type in concentric rings of a reagent module and a rotatory carousel carrying the incubation reaction containers, with adjacent and external arrangement of a module for feeding the disposable reaction containers by means of detachable racks and a scanning device likewise concentric with the carousel, combining with a unit for feeding by pushing the reaction containers from the racks towards the grooves of the incubation carousel, and of two displacement arm devices.
    Type: Grant
    Filed: November 8, 2005
    Date of Patent: November 24, 2009
    Assignee: Grifols, S.A.
    Inventor: Josep Pagés Pinyol
  • Patent number: 7618588
    Abstract: An integrate device includes a heater thermally coupled to a plurality of flow-through tubes to perform thermally-driven chemical reactions. A wire mesh heater is wrapped around each of multiple flow-through tubes, thereby creating a thermal interface between the mesh and the tubes. Each end of the wire mesh is coupled to an electrical contact. The electrical contacts are preferable positioned at an exterior portion of the integrated device to be easily placed in electrical contact with a voltage source. As current passes through the mesh, heat is produced. The heat passes from the mesh to each of the flow-through tubes via the thermal interface. The flow-through tubes can be fluidically coupled to a sample preparation module. The sample preparation module, the flow-through tubes, and the heater can be integrated within a single integrated device that provides automated sample preparation and thermally-driven chemical reactions for a variety of applications.
    Type: Grant
    Filed: August 10, 2005
    Date of Patent: November 17, 2009
    Assignee: Microfluidic Systems, Inc.
    Inventors: Chun-Wah (Phil) Lin, Bob Yuan