Patents Examined by Jasemine C. Chambers, PHD.
  • Method for treating tumors
    Patent number: 5837233
    Abstract: A method is provided for treatment of a mammalian patient having a tumor by administering to the patient allogenic donor lymphocytes that have been co-cultured in the presence of the patient-derived lymphocytes under conditions sufficient to alloactivate the donor lymphocytes. It is preferred that the donor lymphocytes be introduced intralesionally. This method is preferred for treatment of glioblastoma in humans.
    Type: Grant
    Filed: March 15, 1996
    Date of Patent: November 17, 1998
    Assignee: University Of California
    Inventor: Gale A. Granger
  • Mice lacking expression of CTLA-4 receptor
    Patent number: 5714667
    Abstract: Disclosed is a mouse in which expression of the gene encoding the CTLA-4 receptor is suppressed. Also disclosed is a nucleic acid construct useful in preparing such a mouse, and a cell line containing such construct.
    Type: Grant
    Filed: November 6, 1995
    Date of Patent: February 3, 1998
    Assignee: Amgen Canada Inc.
    Inventors: Paul David Waterhouse, Tak Wah Mak