Abstract: Example systems and methods for performing individually customized corneal ablative surgery is presented. The example systems and methods rely on a parametric model that correlates corneal measurements with predicted post-operative results and algorithm updates that facilitate achieving desired post-operative results.

Abstract: Inducing thrombolysis of thermally induced thrombus occurring during endovenous ablation of varicose veins by introducing an optical fiber laser deliver device with optical fiber portion and with an energy emitting tip at its distal end into the varicosed vein to be treated, emitting pulsed, laser energy with sufficient energy to close and destroy varicose veins to the emitting tip of the optical fiber laser delivery device, thereby inducing laser thrombolysis of coagulated blood which accumulates at the energy emitting tip of the fiber when the fiber is caused to emit energy in the presence of uncoagulated blood and minimizing adverse effects associated with thermally induced thrombus within a varicose vein.

Abstract: A system for performing intrastromal ophthalmic laser surgery requires Laser Induced Optical Breakdown (LIOB) of stromal tissue without compromising Bowman's capsule (membrane). In detail, the system is computer-controlled to create symmetrical cuts in the stroma relative to a defined axis of the eye. Importantly, these cuts are all distanced from the axis. The actual location and number of cuts in the surgery will depend on the degree of visual aberration being corrected. Further, the system may create different types of cuts in the stroma. For example, the symmetrical cuts (by type) may include cylindrical, radial or annular layer cuts. The different type cuts may be intersecting or non-intersecting depending on the visual aberration being treated.

Abstract: System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye tissue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist.

Abstract: A flexible wrist-type element and methods of operation thereof, including variations having an angularly moveable hub housing a rotatable and operable end effector driven via a drive train having one or more universal-type joints and/or other flexible couplings moveable via an input mechanism within a housing.

Abstract: System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye tissue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist.

Abstract: A medical system includes an insertion slave apparatus to be inserted into a body, a treatment slave apparatus to be inserted into the body together with the insertion slave apparatus to treat an object, an insertion master portion having a similar figure to the insertion slave apparatus and including a movable portion, wherein the insertion slave apparatus is to perform following actuation according to operation input to the insertion master portion, a treatment master portion to be operated by an operator, wherein the treatment slave apparatus is to perform following actuation according to operation input to the treatment master portion, and a connecting portion coupling the insertion master portion and the treatment master portion to each other, wherein the movable portion is to be moved through the connecting portion to operate the insertion master portion by holding and operating the treatment master portion.

Abstract: A wavefront sensor is integrated with a surgical microscope for allowing a doctor to make repeated wavefront measurements of a patient's eye while the patient remains on an operating table in the surgical position. The device includes a wavefront sensor optically aligned with a surgical microscope such that their fields of view at least partially overlap. The inclusion of lightweight, compact diffractive optical components in the wavefront sensor allows the integrated device to be supported on a balancing mechanism above a patient's head during a surgical procedure. As a result, the need to reposition the device and/or the patient between measuring optical properties of the eye and performing surgical procedures on the eye is eliminated. Many surgical procedures may be improved or enhanced using the integrated device, including but not limited to cataract surgery, Conductive Keratoplasty, Lasik surgery, and corneal corrective surgery.

Abstract: The transplanted cornea attachment method in eye microsurgery and the implant for attaching transplanted corneas, both donor and artificial, without the use of sutures consisting in the cutting of a fragment of the donor tissue (2) and, subsequently, the incision of the corresponding fragment (1) in the recipient tissue (3) so that the donated fragment (2) and the recipient incision (1) have teeth that interlock with each other, and the circular incision (5) in the stroma of the donor and recipient corneal stroma which is less in diameter in the donor tissue and more in diameter in the recipient tissue wherein the fastening implant (4) is subsequently inserted.

Abstract: Two or more telemanipulated surgical instruments are inserted through a guide tube. Each instrument has a transmission mechanism that transmits actuating forces from actuators to components of the instrument. The transmission mechanisms are arranged around an extended centerline of the guide tube and are wedge-shaped so that they can be positioned more closely to the extended centerline.

Abstract: An optical-signal vestibular-nerve stimulation device and method that provides different nerve stimulation signals to a plurality of different vestibular nerves, including at least some of the three semicircular canal nerves and the two otolith organ nerves. In some embodiments, balance conditions of the person are sensed by the implanted device, and based on the sensed balance conditions, varying infrared (IR) nerve-stimulation signals are sent to a plurality of the different vestibular nerves.

Abstract: An apparatus and process using a high-power, short-pulsed thulium laser to output infrared laser pulses delivered through an optical fiber, for cutting and ablating biological tissue. In some embodiments, the pulse length is shortened sufficiently to keep inside the stress-confined ablation region of operation. In some embodiments, the pulse is shortened to near the stress-confined ablation region of operation, while being slightly in the thermal-constrained region of operation. In some embodiments, the laser is coupled to a small low —OH optical fiber (˜100 ?m diameter). In some embodiments, the device has a pulse duration of about 100 ns for efficient ablation; however in some embodiments, this parameter is adjustable.

Abstract: A method and system of treating connective tissue to increase flexibility of the connective tissue or decrease tension in the connective tissue includes forming perforations in the connective tissue to at least 90% of the depth or thickness of the connective tissue and maintaining the perforations in the connective tissue. The method alters the tissue to enhance the fundamental mechanisms involved the immunology, biochemistry, and molecular genetics of the metabolism of the connective tissue.

Abstract: An apparatus for cutting a flap in the cornea of an eye (10) exhibits the following: a laser radiation source for generating laser radiation, means for shaping and guiding the laser radiation in relation to the cornea (20) in such a manner that in the cornea an incision (28) arises which enables a folding of the flap (26) upwards from the cornea. In the process the incision (28) is guided in the hinge region (22) of the cornea in such a way that an undercut arises under the hinge region (22). By this means it is ensured that, in particular in the case of an fs LASIK, the intervention into the stroma is effected substantially symmetrically in relation to a central axis of the cornea (20), so that no undesirable deformations of the cornea result post-operatively by reason of the intraocular pressure.

Abstract: A coupler to provide controller motion from a robotic manipulator includes a pin having a tip with a spherical bearing surface and a plate supported on the spherical bearing surface of the pin with two degrees of rotational freedom about the center of the spherical bearing surface. The plate has a back surface and an opposing driving surface that bears against a first surface of an inner gimbal of a gimbal assembly of a driven device. The plate includes a pin receiving portion that extends outwardly from the driving surface and away from the back surface. The pin receiving portion includes a spherical receiving surface to receive the spherical bearing surface of the pin. The spherical bearing surface is located at a distance above the driving surface such that the center of the spherical bearing surface coincides with an intersection of the gimbal assembly axes of the driven device.

Abstract: There is disclosed a new low-level laser therapy apparatus and method of treating tissue. The invention includes a laser system that uses laser diodes and/or alternatively light emitting diodes (LED's), or both, and a digital interface that gives the operator the ability to generate sine waves or scalar waves as opposed to the simple on/off square waves. The invention also enables the operator to modulate not only the frequency, but also other wave characteristics such as the amplitude and phase. In one aspect, the invention involves modulating the phase relationship between multiple waves by taking one channel or wave which is pulsed through the laser system and then running a second channel or wave in relationship to the first channel, thereby creating a phased relationship, which has been discovered to provide a therapeutic and quantum healing effect on tissue.

Abstract: Embodiments of the present disclosure provides systems, devices, and methods for non-invasively modifying, maintaining, or controlling local tissue optical properties. Methods and devices of the disclosure may be used for optically clearing tissue, for example, for diagnostic and/or therapeutic purposes. A method of optically clearing a tissue may comprise contacting the tissue with an optical clearing device having a base, an array of pins fixed to one side of the base, a brim fixed to the base, an inlet port in the base, an exit port in the base, and a handpiece interface tab fixed to the side of the base opposite the array of pins, applying a mechanical force to the tissue, and illuminating said tissue with at least one wavelength of light through the optical clearing device. A method may further comprise controlling the temperature of the tissue illuminated.

Abstract: An optical-signal vestibular-nerve stimulation device and method that provides different nerve stimulation signals to a plurality of different vestibular nerves, including at least some of the three semicircular canal nerves and the two otolith organ nerves. In some embodiments, balance conditions of the person are sensed by the implanted device or external device, and based on the sensed balance conditions, varying laser nerve-stimulation signals are sent to a plurality of the different vestibular nerves.

Abstract: A light therapy appliance comprises an electronic circuit including Light Emitting Diodes (LEDs) configured to emit light at one or more different wavelengths. A hand held enclosure containing the electronic circuit includes a front lens that directs the multiple different colored lights to a top surface of skin. The light therapy appliance can be programmed for different skin conditions and may be used in conjunction with different topical ointments.

Abstract: An apparatus and method, for selective thermal treatment of tissue, below the surface, while avoiding injury to the superficial layers of the tissue. The apparatus comprises a reflective beam conversion system for providing a pre-selected therapeutic dose of light energy of optimal spectrum and optimal pulse duration to a confined target volumes at predetermined depth under the tissue surface, while reducing the thermal exposure of the surface of the tissue, and the overlying and surrounding tissues. The method is advantageous for treating a variety of medical and dermatological conditions in a safer and more effective manner.