Abstract: Described herein is the use of ribonucleotide reductase inhibitors in the prevention or treatment of restenosis and other vascular proliferative disorders.
Abstract: Tannate compositions containing active pharmaceutical ingredients to be used for treating nausea, vomiting, pain, convulsions, and insomnia and manufacturing processes for preparing the tannate compositions.
Type:
Grant
Filed:
August 9, 2006
Date of Patent:
September 6, 2011
Assignee:
Pernix Therapeutics, LLC
Inventors:
Jeffrey S. Kiel, H. Greg Thomas, Narasimhan Mani
Abstract: In one embodiment a dosage form comprises at least one active ingredient and a molded matrix which comprises 10-100% of a material having a melting point of less than about 100 degrees C. selected from the stamp consisting of thermoplastic polyalkylene oxides, low melting hydrophobic materials, thermoplastic polymers, thermoplastic starches and combinations thereof, and the matrix is capable of providing modified release of the active ingredient upon contacting of the dosage form with a liquid medium. The dosage form may additionally comprise uncoated particles which may contain at least one active ingredient. In another embodiment, a dosage form comprises at least one active ingredient, a plurality of particles and a molded matrix, wherein at least a portion of the particles are coated.
Type:
Grant
Filed:
February 24, 2009
Date of Patent:
July 5, 2011
Inventors:
Shun-Por Li, Harry S. Sowden, David Wynn, Der-Yang Lee, Martin Thomas
Abstract: In one embodiment a dosage form comprises at least one active ingredient and a molded matrix which comprises 10-100% of a material having a melting point of less than about 100 degrees C. selected from the stamp consisting of thermoplastic polyalkylene oxides, low melting hydrophobic materials, thermoplastic polymers, thermoplastic starches and combinations thereof, and the matrix is capable of providing modified release of the active ingredient upon contacting of the dosage form with a liquid medium. The dosage form may additionally comprise uncoated particles which may contain at least one active ingredient. In another embodiment, a dosage form comprises at least one active ingredient, a plurality of particles and a molded matrix, wherein at least a portion of the particles are coated.
Type:
Grant
Filed:
September 28, 2002
Date of Patent:
June 28, 2011
Assignee:
McNeil-PPC, Inc.
Inventors:
Shun-Por Li, Harry S Sowden, David Wynn, Der-Yang Lee, Martin Thomas