Abstract: The disclosure provides a thermotherapy needling instrument with tissue injection, including: a casing, an outer needle, an inner needle and a working needle. The casing has an inlet, an outlet and an inner channel. The outer needle is connected to the casing, and is in communication with the inner channel. The inner needle is disposed in the inner channel of the casing and the outer needle, and the inner needle has at least one opening. The at least one opening is in communication with the inner channel so that the cooling agent flows in circulation. The working needle is connected to the outer needle so as to receive the injectant for injection and tissue ablation. By using the thermotherapy needling instrument, when sampling or injection is required during thermotherapy, the injection efficacy can be achieved by withdrawing the inner needle only. Therefore, efficacy of tissue injection and ablation thermotherapy can be achieved.

Abstract: Methods, systems, and devices are described for setting a dose of medicine and injecting the medicine. In one aspect, a method to dispense a medicine includes inserting a cartridge containing a medicine into a cartridge holder coupled to a housing of a medicine injection device, positioning a spine component of the device to make contact with the cartridge in the cartridge holder, selecting a dose of the medicine for injection, in which the selecting includes rotating an injection component of the device to a setting corresponding to the selected dose, and linearly advancing the injection component to rotate a drive gear coupled to the injection component to drive the spine component so as to push the end of the cartridge to dispense the medicine in the amount of the selected dose.

Abstract: In various embodiments, actuation of a drug-delivery pump is controlled based on a change in a condition of the pump.

Abstract: Fluid transfer devices for use in manual cartridge filling procedures for filling cartridges with liquid drug dosages from medicament containing vials. The fluid transfer devices include a double ended main body having a longitudinal axis, a vial port for telescopic receiving a drug vial and a cartridge port for slidingly receiving a leading cartridge end. The cartridge port includes a cartridge securing arrangement for releasably securing a leading cartridge end therein and a cartridge ejection arrangement for at least partially ejecting a cartridge therefrom for assisting manual sliding ejection of a filled cartridge. The cartridge port can include either a combined cartridge securing and ejection arrangement or a discrete cartridge securing arrangement and a discrete cartridge ejection arrangement.

Abstract: An infusion pump for continuously conveying a fluid includes an inlet, an outlet, a first piston movably supported in a first chamber connected to the inlet, a second piston movably supported in a second chamber connected to the outlet, and a connecting channel connecting the first chamber to the second chamber. At least one control element, in a first position, connects the inlet to the first chamber and, in a second position, connects the first chamber to the second chamber. A controller acts upon the first piston, the second piston, and the control element so that, when the control element is set in the first position, the first chamber is filled while the second chamber is drained, and when in the second position, the first chamber is drained and the second chamber is filled, wherein a constant discharge at the outlet is maintained at a predefined flow rate.

Abstract: A dual one-way check valve arrangement (300) that may be used for assessing an operating condition of at least one of first and second check valves (304, 308) situated in series along/within a section of a patient-specific section of tubing (244). A pressure sensor (332) may be associated with at least part of the flow path between the first and second check valves (304, 308) and may be operable to provide an indication of a failed condition of at least one of the first and second check valves (304, 308). In one embodiment, the pressure sensor (332) may change from a first state to a second state upon fluid pressure within the flow path between the first and second check valves (304, 308) falling below a predetermined level. For instance, the predetermined level may be a cracking pressure of at least one of the first and second check valves (304, 308). The change in state may be visually discernible on an exterior of the pressure sensor (332).

Abstract: A balloon trocar includes a cannula assembly including a cannula and an outer sleeve fitting over the cannula. The distal end of the outer sleeve is proximal to the distal end of the cannula. A balloon is coupled to a distal portion of the sleeve and a distal portion of the cannula. The outer surface of the cannula includes a plurality of longitudinal channels for transmitting gas or fluid to the balloon. A bolster having a gel pad at its distal portion is slidably mounted to the cannula assembly and may be locked in a desired position. In use, the trocar is inserted into an incision through a body wall and into a body cavity. The balloon is inflated and the cannula assembly pulled proximally against the incision while the bolster is slid distally to the body wall and locked in place to seal the incision with the compressed balloon.

Abstract: The present invention provides a device for injection of formulations into a patient. In one embodiment the injection is sub-cutaneous. The device is convenient for injecting viscous formulations that would otherwise clog conventional injection devices, for example formulations containing microspheres, suspensions, and other viscous substances. Generally, the device features a needle for piercing the skin, an internal chamber for holding and transmitting fluid, a plunger for applying pressure to the internal chamber, a switch for triggering withdrawal of the needle, a sheath at least partially encompassing the needle and having a flow path within the sheath, and a spring that expands when the switch is triggered, and which thereby at least partially withdraws the needle from the sheath.

Abstract: A first drug delivery system includes first and second drug-container holders and first and second pump assemblies. The first (second) holder is adapted to receive a first (second) drug container having a first (a different second) dimensioned shape but not a second (first) drug container having a different second (a first) dimensioned shape. A second drug delivery system includes first and second bar code scanners, first and second drug-container holders, and first and second pump assemblies. The first (second) holder is adapted to receive a first (second) drug container having a dimensioned shape and to orient a positioned first (second) bar code of the first (second) drug container to face the first (second) bar code scanner because of the dimensioned shape. In one application, the first drug is a sedative drug, the second drug is an analgesic drug, and the drugs are used during a conscious sedation medical procedure.

Abstract: A cassette (1) that is insertable into an infusion pump for delivery of a fluid to a subject that has a housing with two ends for holding flexible tubing (75) through which the fluid is directed. The housing has an open area exposing the tubing, which engages a pumping mechanism when inserted into an infusion pump. An anti-flow valve mechanism (100) associated with the tubing or the cassette and present either in, on or near the housing is made up of a piston (103/105) and spring (110), where the spring biases the piston against the tubing to prevent fluid flow.

Abstract: A medicated module attachable to a drug delivery device comprises a connecting body configured for attachment to the drug delivery device. A first needle is fixed within the connecting body and a movable needle hub is operatively coupled to the connecting body. A needle guard is operatively coupled to the connecting body and a biasing member is positioned between the connecting body and needle guard. A second needle is fixed within the needle hub. A first cavity within the connecting body defines a reservoir containing at least one dose of a medicament. The reservoir configured for fluid communication with the first and the second needle. The reservoir comprises a bypass configured to allow medicament from the drug delivery device to bypass the reservoir and exit the second needle.

Abstract: A skin gripping means for use with an injector (200) is disclosed. In one embodiment the skin gripping means is a needle guard (100). An exterior surface (7) of the skin gripping means (100) is provided with a plurality of fingers (6) adapted to engage a subject's skin (9) when in use. A method of performing a subcutaneous injection is also disclosed with includes the steps of bringing a skin gripping means (100) of an injector (200) into contact with the skin (9) of a subject, moving the skin gripping means (100) substantially parallel to the skin (9) to thereby form a fold (10) in the skin, moving a needle (11) of the injector (200) into the fold (10) to a suitable position for a subcutaneous injection and injecting a substance through the needle (11).

Abstract: A method for exchanging heat between a primary fluid (W) and a secondary fluid (X) and a heat exchanger for heat exchange as well as an arrangement and a kit comprising a heat exchanger. The heat exchanger comprises a first and a second fluid circuit extending through the heat exchanger. The heat exchanger further comprises a stack of fluid plates and a membrane arranged between each of the fluid plates where one interspace is formed between each fluid plate and membrane. The first and the second fluid circuit are each constituted by a passage extending through the fluid plates and membranes and along the fluid plates and membranes in at least two interspaces. A primary fluid (W) is passed through the first fluid circuit and a secondary fluid (X) is passed through the second fluid circuit such that the primary fluid (W) is passed along one side of a membrane and simultaneously the secondary fluid (X) is passed along the other side of the membrane.

Abstract: The invention provides a manual breast pump which can be disassembled and assembled easily for cleaning purposes, and which can readily modify a negative pressure during expression of milk generated by a lever-type operating section. A breast pump having an accommodating vessel for collecting breast milk, a breast pump main body, and an operating section attached to the breast pump main body and for deforming a negative pressure generating member installed on the breast pump main body, wherein the operating section has a lever form and includes an engagement opening as an engaged section for engaging with an engaging section provided on the breast pump main body, and the engagement opening is selectively engaged with engaging sections in a plurality of positions provided midway on an extending section erected in a pillar shape as one portion of the negative pressure generating member.

Abstract: A therapeutic implantable device comprises a biodegradable outer shell, a plurality of spaced biodegradable layers within the outer shell, a first therapeutic mass between the plurality of spaced biodegradable layers and a second therapeutic mass between the plurality of spaced biodegradable layers. The plurality of spaced biodegradable layers are arranged such that the first therapeutic mass is exposed external to the implantable device before exposure of the second therapeutic mass external to the implantable device.

Abstract: An electrosurgical device is configured for connection to a source of electrosurgical energy and includes a housing and an electrical circuit supported within the housing. The electrical circuit is connectable to the source of electrosurgical energy. The electrical circuit is provided with at least one tactile enhancement feature. A controller is slidably supported on the housing. The controller is configured to exert a force on the electrical circuit to affect a change in the electrical circuit and to exert a force on a surface of the housing to engage the tactile enhancement feature and provide a tactile feedback to a user of the electrosurgical device as the controller is moved relative to the housing.

Abstract: In various embodiments, actuation of a drug-delivery pump is controlled based on a change in a condition of the pump.

Abstract: Infusion systems for holding an infusion pump on the body of a user are provided. According to one embodiment, the infusion system includes: a carrier frame; a guiding member disposed on the carrier frame; and a linear guide on the infusion pump wherein, when the infusion pump is attached to the carrier frame, the guiding member and the linear guide mate with each other to hold the infusion pump in place.

Abstract: A catheter comprises an elongated carrier and a balloon carried by the carrier in sealed relation thereto. The balloon has an outer surface and is arranged to receive a fluid therein that inflates the balloon. The catheter further comprises a shock wave generator within the balloon that forms mechanical shock waves within the balloon, and a medicinal agent carried on the outer surface of the balloon. The medicinal agent is releasable from the balloon by the shock waves.

Abstract: Medical device assemblies capable of aspirating liquid into a syringe barrel or other medical devices while evacuating any air from the syringe are described. An exemplary medical device includes a syringe barrel, plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within either the stopper or the plunger rod. Described is a medical device including a syringe barrel, plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within chamber between the stopper and plunger rod wherein the plunger rod includes a sealing edge and is moveable relative to the stopper. Exemplary medical devices may include a vent for allowing air that permeates through the porous portion to escape to atmosphere. Methods for aspirating a syringe barrel with a liquid are also provided.