Patents Examined by Jennifer Kim
  • Treatment of skin damage using olive oil polyphenols
    Patent number: 6437004
    Abstract: Free radical-scavenging olive oil polyphenols are topically applied to treat skin damage, such as contact dermatitis (particularly diaper area dermatitis), atopic dermatitis, xerosis, eczema (including severe hand and foot eczema), rosacea, seborrhea, psoriasis, thermal and radiation burns, other types of skin inflammation, and aging. Typical compositions contain from about 0.25% to about 10% of a polyphenol preparation obtained from olive oil.
    Type: Grant
    Filed: May 7, 2001
    Date of Patent: August 20, 2002
    Inventor: Nicholas V. Perricone
  • Pharmaceutical compositions, mainly vaginal suppository, containing many different active ingredients
    Patent number: 6432935
    Abstract: Compositions comprising an antibiotic, sulphonamide, at least one an antiquagul agent, e.g., clotrimazol (bis-phenyl-(2-chlorophenyl)-1-imidazolyl-methane), natamycin, or nystatin,and 5-nitro-metronidazol (5-nitro-inidazoles) e.g., (metronidazol or tinidazol or nimorazol) and a pharmaceutically acceptable carrier. The compositions are useful mainly as vaginal suppositories.
    Type: Grant
    Filed: January 22, 1997
    Date of Patent: August 13, 2002
    Inventor: Márton Milánkovits
  • Oil in water microemulsion
    Patent number: 6426078
    Abstract: The invention is concerned with a microemulsion of the oil-in water type, containing at least one polyglycerol ester as the emulsifier and at least one lipophilic substance as the internal phase. The emulsifier contains a triglycerol monofatty acid ester and the lipophilic substance is one from the group carotenoids, especially, &bgr;-carotene, vitamins A, D, E and K and their derivatives and polyunsaturated fatty acids.
    Type: Grant
    Filed: February 26, 1998
    Date of Patent: July 30, 2002
    Assignee: Roche Vitamins Inc.
    Inventors: Kurt Bauer, Clarissa Neuber, Axel Schmid, Karl Manfred Völker
  • Formulations and methods for providing prolonged local anesthesia
    Patent number: 6426339
    Abstract: The use of glucocorticosteroids in methods and formulations for prolonging and/or reactivating local anesthesia or local anesthesia previously induced by a local anesthetic agent, is disclosed.
    Type: Grant
    Filed: April 3, 2000
    Date of Patent: July 30, 2002
    Assignee: Children's Medical Center Corporation
    Inventors: Charles B. Berde, Robert S. Langer, Joanne Curley, Jenny Castillo
  • Topical delivery systems for active agents
    Patent number: 6419913
    Abstract: This invention relates to a method for enhancing the transmembrane penetration of benefit agents using a certain non-ionic lipid/surfactant-containing formulation as an enhancing agent, and the compositions used therein. Various active agents, such as anti-dandruff agents, hair growth agents, hair inhibitor agents, anti-acne agents, anti-aging agents, depilatory agents, and depigmentation agents, may be effectively delivered into the skin, hair follicles and sebaceous glands using the compositions of the present invention.
    Type: Grant
    Filed: July 26, 2001
    Date of Patent: July 16, 2002
    Assignee: Johnson & Johnson Consumer Companies, Inc.
    Inventors: Susan M. Niemiec, Jonas C. T. Wang, Stephen J. Wisniewski, Kurt S. Stenn, Gwang Wei Lu
  • Method for the broad based treatment of infections especially infections of organs such as the skin and vagina
    Patent number: 6420425
    Abstract: A method for treating and preventing infections, bacterial, fungal, insecticidal, parasitic and actinomycotic in origin, especially infections of organs such as the vagina and skin. The methods involves administering to a patient in need thereof a composition comprising a combination of boric acid and acetic acid, in effective amounts. Such a composition is especially useful as a broad based treatment and prevention of vaginal and skin infections of unknown origin and can be used without the need for medical diagnosis or while such a diagnosis is being determined. Such a composition is effective, safe, economical and environmentally friendly, and provides an alternative to existing forms of treatment which are toxic which may cause undesirable side effects.
    Type: Grant
    Filed: July 2, 1999
    Date of Patent: July 16, 2002
    Inventor: Steven A. Melman
  • 2-arylbenzo[b]thiophenes useful for the treatment of estrogen deprivation syndrome
    Patent number: 6395769
    Abstract: This invention provides methods which are useful for the inhibition of the various medical conditions associated with estrogen deprivation syndrome including osteoporosis and hyperlipidemia utilizing compounds of formula I:
    Type: Grant
    Filed: May 12, 2000
    Date of Patent: May 28, 2002
    Assignee: Eli Lilly and Company
    Inventor: George Joseph Cullinan
  • Method for preventing diarrhea
    Patent number: 6395708
    Abstract: The present invention relates to a method for preventing irinotecan-induced or camptothecin-induced or camptothecin- analog-induced diarrhea by administering an effective amount of octreotide. In particular the invention concerns new methods, combination formulations and kits to prevent late diarrhea caused by irinotecan or camptothecin, or camptothecin-analog administration.
    Type: Grant
    Filed: August 25, 2000
    Date of Patent: May 28, 2002
    Assignees: Novartis, A.G., Pharmacia & Upjohn Co.
    Inventors: Langdon L. Miller, John David Rothermel, Hugh Michael O'Dowd
  • Pharmaceutical composition
    Patent number: 6387918
    Abstract: A pharmaceutical composition comprising a tricyclic compound (I) or its pharmaceutically acceptable salt, an oil substance, a surfactant, a hydrophilic substance, water, and optionally a pH control agent, with enhanced stability, absorbability and/or a low irritation potential, is provided.
    Type: Grant
    Filed: August 20, 1999
    Date of Patent: May 14, 2002
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masayuki Yamanaka, Fumio Shimojo, Satoshi Ueda, Toshihiko Toyoda, Rinta Ibuki, Norio Ohnishi
  • QT dispersion and heart rate variability improvement with CRF antagonists to prevent sudden death
    Patent number: 6384039
    Abstract: A method of preventing sudden death which comprises administering to a mammal, including a human, a therapeutically effective amount of a corticotropin releasing factor antagonist.
    Type: Grant
    Filed: March 31, 2000
    Date of Patent: May 7, 2002
    Assignee: Pfizer Inc.
    Inventor: Anthony A. Fossa
  • Pharmaceutical, cosmetic and/or food composition with antioxidant properties
    Patent number: 6376498
    Abstract: A pharmaceutical, cosmetic, and/or food composition containing a pyrazine derivative useful for preparing a medicament for preventing and/or treating pathologies related to the activity of oxygen promoters or for treating cancer tumors. The pathologies which can be treated include inflammatory diseases, carcinogenic diseases, atherosclerosis, or cancerous tumors. The pyrazine may be coelenteramine or its derivatives.
    Type: Grant
    Filed: February 14, 2000
    Date of Patent: April 23, 2002
    Assignee: Universite Catholique de Louvain
    Inventors: Jean-Francois Rees, Marléne Dubuisson, André Trouet
  • Soy-based nutritional products
    Patent number: 6372782
    Abstract: The present invention relates generally to a complete nutritional product that provides soy protein and enhanced levels of isoflavones. Preferably, the soy protein comprises at least 0.7 mg isoflavones/gm soy protein and at least 0.5 mg genistein/gm soy protein. The product is fortified at 35% of the RDI for calcium and contains an antioxidant package. The invention also describes the method to produce a heat stable isoflavone-enriched soy protein complete nutritional.
    Type: Grant
    Filed: June 18, 1999
    Date of Patent: April 16, 2002
    Assignee: Abbott Laboratories
    Inventors: Guaravkumar C. Patel, Michael Allen Chandler, Kent Lee Cipollo, Lisa Diane Craig, Theresa W. Lee
  • Benzimidazole analogs as down-regulators of IgE
    Patent number: 6369091
    Abstract: This invention relates to a family of diacyl benzimidazole analogs, which are inhibitors of the IgE response to allergens. These compounds are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic.
    Type: Grant
    Filed: October 21, 1999
    Date of Patent: April 9, 2002
    Assignee: Avanir Pharmaceuticals
    Inventors: Jagadish C. Sircar, Mark L. Richards, Michael G. Campbell, Michael W. Major
  • Methods for the treatment of tinnitus and other disorders using R(?)ketoptofen
    Patent number: 6362227
    Abstract: Methods of treating neuropathic pain, tinnitus, and related disorders are disclosed. These methods comprise the administration of optically pure R(−)-ketoprofen. Also disclosed are pharmaceutical compositions useful in the treatment of neuropathic pain and tinnitus which comprise optically pure R(−)-ketoprofen.
    Type: Grant
    Filed: February 22, 2000
    Date of Patent: March 26, 2002
    Assignee: Sepracor, Inc.
    Inventors: Thomas P. Jerussi, Paul D. Rubin
  • Lotion compositions utilizing capsaicin
    Patent number: 6348501
    Abstract: A lotion for treating the symptoms of arthritis using capsaicin and an analgesics, and a method for making.
    Type: Grant
    Filed: September 15, 2000
    Date of Patent: February 19, 2002
    Assignee: Medical Merchandising, Inc.
    Inventors: Stephen D. Holt, Teresa Leigh Barr
  • Method for treating celiac disease
    Patent number: 6348495
    Abstract: A method for treating celiac disease comprising administration of a composition containing an alkanoyl L-carnitine wherein the alkanoyl group is straight or branched and has 2-6 carbon atoms and the pharmacologically acceptable salts thereof.
    Type: Grant
    Filed: July 26, 2000
    Date of Patent: February 19, 2002
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Claudio Cavazza, Luigi Mosconi
  • Use of central cannabinoid receptor antagonists for regulating appetence
    Patent number: 6344474
    Abstract: The invention relates to the use of a central cannabinoid receptor antagonist, by itself or in association with a compound for regulating metabolic disorders, especially a &bgr;3-adrenergic receptor agonist, for the preparation of drugs useful in the treatment of appetency disorders.
    Type: Grant
    Filed: August 19, 1999
    Date of Patent: February 5, 2002
    Assignee: Sanofi-Synthelabo
    Inventors: Jeanne Maruani, Philippe Soubrie
  • Methods for inhibiting mastocytosis
    Patent number: 6339100
    Abstract: A method of preventing or treating in a subject mastocytosis which comprises administering to the subject a therapeutically effective amount of a compound having the structure: or a pharmaceutically acceptable salt thereof so as to thereby prevent or treat mastocytosis in the subject.
    Type: Grant
    Filed: December 29, 1999
    Date of Patent: January 15, 2002
    Assignee: The Trustees of Columbia University in the City of New York
    Inventor: B. Jack Longley
  • Methods of pharmacological treatment using S(?) amlodipine
    Patent number: 6333342
    Abstract: Methods and compositions are disclosed utilizing the optically pure S(−) isomer of amlodipine. This compound is a potent drug for the treatment of hypertension while avoiding the concomitant liability of adverse effects associated with the administration of the racemic mixture of amlodipine. The S(−) isomer of amlodipine is also useful for the treatment of angina and such other conditions as may be related to the activity of S(−) amlodipine as a calcium channel antagonist without the concomitant liability of adverse effects associated with the racemic mixture of amlodipine.
    Type: Grant
    Filed: November 4, 1999
    Date of Patent: December 25, 2001
    Assignee: Isotechnika, INC
    Inventor: Robert T. Foster
  • Method of treating benign positional vertigo
    Patent number: 6333352
    Abstract: A process and product for treating benign positional vertigo with anti-epileptic drugs such as divalproex sodium or gabapentin.
    Type: Grant
    Filed: April 5, 2000
    Date of Patent: December 25, 2001
    Assignee: Mimicking Man Manually, Inc.
    Inventor: Iraj Derakhshan