Patents Examined by Jennifer Kolb
  • Patent number: 6187370
    Abstract: A device useful for localized delivery of a therapeutic material is provided. The device includes a structure including a porous material; and a water-insoluble salt of a therapeutic material dispersed in the porous material. The water-insoluble salt is formed by contacting an aqueous solution of a therapeutic salt with a heavy metal water-soluble salt dispersed throughout a substantial portion of the porous material. The porous material can be made of a polymer other than fibrin with fibrin incorporated into the pores, which can be the only layer of polymeric material on the medical device (e.g., stent). A new method for preparing a porous polymer material on a medical device.
    Type: Grant
    Filed: September 16, 1999
    Date of Patent: February 13, 2001
    Assignee: Medtronic, Inc.
    Inventors: Thomas Q. Dinh, Rodney G. Wolff, Eric P. Berg
  • Patent number: 6187387
    Abstract: The invention relates to a method of protecting wood against light-induced degradation by treatment with a stain or impregnation which penetrates the surface of the wood comprising a) at least one organic solvent; b) a hindered amine compound of formula I or II  where G1 and G2 are independently alkyl of 1 to 4 carbon atoms or are together pentamethylene, Z1 and Z2 are each methyl, or Z1 and Z2 together form a linking moiety which may additionally be substituted by an ester, ether, hydroxy, oxo, cyanohydrin, amide, amino, carboxy or urethane group, E is oxyl or hydroxyl, X is an inorganic or organic anion, and where the total charge of cations h is equal to the total charge of anions j.
    Type: Grant
    Filed: March 11, 1999
    Date of Patent: February 13, 2001
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Thomas Bolle, Jean-Pierre Wolf, Raymond Seltzer
  • Patent number: 6183814
    Abstract: A coated paper product including a paper layer and a polymer layer, wherein the polymer layer includes a polylactide polymer composition having a ratio of Mz to Mn of greater than about 6. The polymer composition, when melted, exhibits a die swell of greater than about 1.25 for a melt flow index of greater than about 2. Polymer lactide compositions, methods of manufacturing the polymer composition and the coated paper product, and articles produced therefrom are also described.
    Type: Grant
    Filed: May 23, 1997
    Date of Patent: February 6, 2001
    Assignee: Cargill, Incorporated
    Inventors: James Nangeroni, Mark H. Hartmann, Matthew L. Iwen, Christopher Michael Ryan, Jeffrey J. Kolstad, Kevin T. McCarthy
  • Patent number: 6180162
    Abstract: An excellent antibacterial property is afforded upon a metallic article by simple steps of coating a dispersion liquid or a solution of fine particles made of an antibacterial ingredient on the surface of the metallic article and pressing the resulting coated surface of the metallic article under a non-heated condition or rubbing the resulting coated surface of the metallic article. In addition, a conventional rolling step or the like can be used itself without any change in the above treatment, which is economically extremely advantageous. Furthermore, since the antibacterial metallic article according to the present invention is obtained under the non-heated condition, the antibacterial ingredient is not deteriorated. Further, since the antibacterial property is not lost through some abrasion, excellent antibacterial property can be exhibited over an extended time period. Further, there is no fear that surface characteristics of the metallic article, for example, a tone of color will change.
    Type: Grant
    Filed: July 6, 1999
    Date of Patent: January 30, 2001
    Assignees: Sumitomo Osaka Cement Co., Ltd., Kawasaki Steel Corporation
    Inventors: Keijiro Shigeru, Yoshitomo Inoue, Takeshi Yokota, Misako Tochihara, Susumu Satoh
  • Patent number: 6179817
    Abstract: Disclosed are hybrid coatings for implantable medical devices. Such coatings include a first layer of an aqueous dispersion or emulsion of an organic acid functional group containing polymer, a crosslinker and a therapeutic agent dispersed therein. The coating also includes a second layer of an aqueous solution or dispersion of an organic acid functional group-containing bio-active agent. The hybrid coatings are especially suited for preventing restenosis of endoprostheses by the combined action of the therapeutic agent and the bio-active agent. Methods of making and using devices coated with such compositions are also provided.
    Type: Grant
    Filed: January 28, 1999
    Date of Patent: January 30, 2001
    Assignee: Boston Scientific Corporation
    Inventor: Sheng-Ping Zhong
  • Patent number: 6177125
    Abstract: A method is described for manufacturing coated tablets made of tablet cores and coating granulate using a press that has at least one compression chamber with preferably an upper and a lower punch and a feeding device for tablet cores. The method according to the invention is characterized by the fact that before the coating granulate is compressed, at least one pasty tablet core is added to the coating granulate to be compressed and in that the coating granulate and tablet core(s) are compressed in a single compression step.
    Type: Grant
    Filed: April 29, 1997
    Date of Patent: January 23, 2001
    Inventor: Gunter M. Voss
  • Patent number: 6171653
    Abstract: An apparatus applies a liquid or viscid coating medium onto a moving material web, especially one made of paper or cardboard. A coating mechanism first applies the coating medium onto an applicator element or an applicator roll, which subsequently transfers the coating medium at a coating location onto the material web in the form of a coating layer. Furthermore, if so desired, a doctoring device can be positioned at a doctor station, adjacent to the coating location, on the downstream side relative to the movement of the material web for the purpose of smoothing and/or metering the coating. The coating apparatus incorporates an apparatus for the generation and/or supplying of a fluid, preferably steam. This apparatus is positioned adjacent to the coating location or to the doctor station on the downstream side relative to the movement L of the material web.
    Type: Grant
    Filed: January 8, 1999
    Date of Patent: January 9, 2001
    Assignee: Voith Sulzer Papiertechnik Patent GmbH
    Inventors: Bernhard Kohl, Martin Kustermann, Oswald Satzger, R{umlaut over (u)}diger Kurtz, Harald Hess, Karl-Heinz Hannen, Hans Peter Hoffmann, Franz Kustos
  • Patent number: 6165541
    Abstract: An improvement in the immunofixation electrophoresis procedure for detecting proteins in serum, urine or cerebral spinal fluids. Samples are placed on a gel and subjected to electrophoresis for resolving or separating proteins. Thereafter, antisera are applied to the sample areas through openings located on a template. The template includes projections and, the template substantially precludes cross-contamination and the adverse effects of ambient conditions on the integrity of the fluid, such as by the projections contacting, depressing or cutting into the gel to form closed cavities.
    Type: Grant
    Filed: April 29, 1999
    Date of Patent: December 26, 2000
    Assignee: Helena Laboratories Corporation
    Inventors: Mark E. Merchant, Philip A. Guadagno, Suzan Robinson
  • Patent number: 6165561
    Abstract: This invention relates to a process for the production of a multilayer lacquer coating on a substrate having an autophoretically coatable, metallic surface, in which a first priming coat of an autophoretically depositable coating composition is autophoretically deposited and then stoved and one or more subsequent coats are then applied by spraying, wherein the autophoretically depositable coating composition contains one or more constituents having an adhesion promoting action and/or wherein before one or more further coats are applied by spraying, the stoved priming layer produced by autophoretic deposition is physically and/or chemically treated and/or provided with an adhesion promoting coat.
    Type: Grant
    Filed: May 17, 1999
    Date of Patent: December 26, 2000
    Assignee: Herberts GmbH
    Inventors: Joachim Blum, Dieter Engel, Klausjorg Klein, Walter Kuhhirt, Bettina Vogt-Birnbrich
  • Patent number: 6165545
    Abstract: A method is provided for after-treating fabric with a fluoroacrylate emulsion by immersion, typically under poorly-controlled conditions (e.g. field conditions), and a second embodiment of this method is provided for treating large, previously manufactured items comprising fabric (e.g. upholstered furniture, tents, awnings, and the like) with an aerosol spray containing micrometer or submicrometer-sized droplets of a diluted version of the fluoroacrylate emulsion. In both embodiments, the fluoroacrylate emulsion contains, dispersed therein with the aid of a surfactant system containing an amphoteric surfactant, essentially a single particulate fluoroacrylate copolymer having repeating units of the formulas I and II ##STR1## wherein R.sub.f is a fluorinated alkyl radical; R and R.sup.1 are hydrogen or alkyl; and R.sup.2 is hydrogen or substituted or unsubstituted alkyl. The aqueous dispersion further contains, in addition to the surfactant system, a minor amount of polar organic liquid.
    Type: Grant
    Filed: August 12, 1999
    Date of Patent: December 26, 2000
    Assignee: Ricard J. Moody
    Inventor: Richard J. Moody
  • Patent number: 6162493
    Abstract: A process is disclosed for the preparation of a heat mode recording element of the DRAW type (Direct Read After Write), said process comprising the following steps:(A) providing a material having following layer arrangement, in order:(1) a transparent support optionally subbed,(2) a thin metal layer coated from an aqueous medium containing metal particles,(3) a coated single top layer curable by radiation,(B) radiation curing said coated single top layer (3).In the preferred embodiment of the present invention the metal layer is a bismuth layer.
    Type: Grant
    Filed: November 23, 1998
    Date of Patent: December 19, 2000
    Assignee: Agfa-Gevaert, N.V.
    Inventors: Luc Leenders, Eddie Daems, Hieronymus Andriessen
  • Patent number: 6162505
    Abstract: The present invention relates to a process for coating mineral moldings with film-forming aqueous formulations in which in succession at least one 1st formulation comprising at least one copolymer P1 as binder and at least one inorganic pigment is applied to the mineral molding and, if desired, is dried and then at least one 2nd formulation comprising at least one copolymer P2 as binder and, if desired, inorganic pigment is applied, the copolymers P1 and P2 each being composed of monomers A, B and, if desired, C, wherein identical monomers A and B are selected in each case for the copolymers P1 and P2 and the 1st. formulation has a pigment volume concentration which is greater by at least 10 than that of the 2nd formulation, and to a composition of said 1st and 2nd formulations and to the use of said 1st and 2nd formulations for coating mineral moldings.
    Type: Grant
    Filed: March 8, 1999
    Date of Patent: December 19, 2000
    Assignee: BASF Aktiengesellschaft
    Inventors: Manfred Schwartz, Bertold Bechert
  • Patent number: 6159531
    Abstract: A multi-step method for surface modification of a medical device having at least one surface exposed to tissue and/or blood. The steps comprise a low temperature plasma treatment of the said surface to provide a plasma deposited layer having functional groups. A chemical treatment of the plasma deposited layer using multifunctional linkers establishes covalent bonds with the plasma deposited layer. A bioactive/biocompatible agent react with the multifunctional linkers so that molecules thereof are covalently bound to said surface.
    Type: Grant
    Filed: August 30, 1999
    Date of Patent: December 12, 2000
    Assignee: CardioVasc, Inc.
    Inventors: Mai Huong Dang, Phillip Chiu
  • Patent number: 6159551
    Abstract: A spray wax concentrate adapted to be applied in a highly diluted state in an aqueous spray to a surface, such as a vehicle surface, in the hot sun comprising about 2 to 10 wt. % of a fine polishing powder, of about 10 to about 40 wt. % of mineral spirits, of about 0.5 to about 3 wt. % of a dimethyl silicone fluid polymer, from about 0.5 to about 1.75 wt. % of an alkanolamide surface-active agent; from about 1 to about 1.75 wt. % of a higher alkyl amino functional group substituted dimethyl silicone polymer wax, and the balance, water, to obtain a total of 100 wt. %. The spray wax concentrate is preferably applied as pressurized, turbulent aqueous spray containing about 1 part by volume of the spray wax concentrate and about 40 to about 100 parts by volume of water.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: December 12, 2000
    Assignee: John Yeiser
    Inventors: John Yeiser, Robert M. Marchese
  • Patent number: 6156381
    Abstract: A method for preparing a surface modified gas separation membrane, wherein said membrane has improved permselective properties for separating a mixture of gases as compared to the unmodified membrane, is described. The method comprises coating a surface unmodified gas separation membrane with a solution of a coating material, wherein the coating material is an organic material having at least one site of unsaturation; heating the coated gas separation membrane; and contacting the heated coated gas separation membrane with at least one oxidizing agent for a time effective to surface modify the gas separation membrane to produce the surface modified gas separation membrane having improved permselectivity.
    Type: Grant
    Filed: December 30, 1998
    Date of Patent: December 5, 2000
    Assignee: MG Generon
    Inventors: Pamela J. Leong, Frederick L. Coan, John A. Jensvold, Thomas O. Jeanes
  • Patent number: 6156377
    Abstract: Provided is a low-priced metal coating treatment which causes less pollution, wherein the dispersion of ceramics and the forming of a metal coat are performed by blasting treatment; and a ceramic dispersion plating process making it possible to improve wear resistance, heat resistance and the like of a workpiece and the adhesion of the metal coat. When ceramic particles are ejected on the surface of a workpiece comprising a metal or a metal component by blasting, the workpiece is heated and softened so that the ceramic particles are dispersed inside the workpiece to form a dispersed layer. When a coating metal powder is further ejected thereon by blasting, the temperature of the dispersed layer rises in the same way so that elements in the composition of the coating metal powder diffuse and penetrate inside/on the surface of the dispersed layer to form a plating layer.
    Type: Grant
    Filed: January 7, 1999
    Date of Patent: December 5, 2000
    Assignee: Fuji Kihan Co., Ltd.
    Inventor: Yoshio Miyasaka
  • Patent number: 6156387
    Abstract: The invention relates to a process for the thermomechanical surface treatment of flat webs of material, particularly those made of paper and carton, and to agents for performing said process. According to the process of the invention, adhesion between the flat web of material and the surface of the tool used in thermomechanical surface treatment, e.g., a roll or a press, is reduced or prevented by using an abhesive agent, which contains dicarboxylic dialkyl esters and/or diisoalkyl esters of C.sub.2 -C.sub.12 dicarboxylic acids with C.sub.1 -C.sub.13 n- and/or iso-alkanols as component with abhesive effect. The abhesive agent is preferably employed as an oil-in-water emulsion and is either applied to the surface of the tool used in said thermomechanical treatment or is added to the impregnating fluid or the paper coating mass or the moistening water or the steam in pre-moistening, or is applied to the paper web after the impregnating unit or directly before the smoothing roll.
    Type: Grant
    Filed: November 5, 1998
    Date of Patent: December 5, 2000
    Assignees: Stockhausen GmbH & Co. KG, Kaemmerer GmbH
    Inventors: Joachim Werres, Bernd Reinhardt
  • Patent number: 6156373
    Abstract: Devices and methods for applying a polymeric coating to a medical device. The steps of the coating process including applying a liquid polymeric material to the surface of the medical device, then directing a stream of gas to impinge on the surface of the medical device. Excess liquid polymeric material is removed from the surface of the medical device. The devices used in the coating process and the coated medical device are also part of this invention.
    Type: Grant
    Filed: May 3, 1999
    Date of Patent: December 5, 2000
    Assignee: SciMed Life Systems, Inc.
    Inventors: Sheng-ping Zhong, Vladimir B. Tsukernik
  • Patent number: 6153252
    Abstract: A process is provided for coating stents having a first and second surface with passages there between to avoid blockage and bridging of the passages. The process comprises contacting the stent with a liquid coating solution containing a film forming biocompatible polymer under conditions suitable to allow the film forming biocompatible polymer to coat at least one surface of the stent while maintaining a fluid flow through said passages sufficient prevent the film forming biocompatible polymer from substantially blocking said passages. Also described are stents coated by this process.
    Type: Grant
    Filed: April 19, 1999
    Date of Patent: November 28, 2000
    Assignee: Ethicon, Inc.
    Inventors: Syed F. A. Hossainy, Mark B. Roller, Gerard H. Llanos, Gregory A. Kopia
  • Patent number: 6149972
    Abstract: Intercalated graphite flake which has enhanced exfoliation volume characteristics at relatively low exfoliation temperatures e.g. 600.degree. C. is made by heating a blend of intercalated particles and an organic reducing agent in the temperature range of 25.degree. to 110.degree. C.
    Type: Grant
    Filed: January 29, 1998
    Date of Patent: November 21, 2000
    Assignee: UCAR Graph-Tech. Inc.
    Inventor: Ronald Alfred Greinke