Patents Examined by Jennifer L. Overly
  • Methylated control DNA
    Patent number: 11345949
    Abstract: Provided herein is technology relating compositions and methods for analysis of methylated DNA from a subject. The technology also relates to use of endogenous methylated DNAs as internal controls for marker gene methylation assays.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: May 31, 2022
    Assignee: Exact Sciences Corporation
    Inventors: Hatim T. Allawi, Graham P. Lidgard
  • Biomarkers for predicting degree of weight loss
    Patent number: 11299784
    Abstract: The present invention relates to a method for predicting the degree of weight loss attainable by applying one or more dietary interventions to a subject and/or the degree of maintenance of weight loss following one or more dietary interventions; which method comprises determining the level of microRNA-486 (miR-486) in one or more samples obtained from the subject; and/or determining the nucleotide of the subject at one or more polymorphic positions genetically linked to miR-486.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: April 12, 2022
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Armand Valesia, Jorg Hager, Jerome Carayol
  • RhD gene allele associated with a weak D phenotype and its uses
    Patent number: 11248261
    Abstract: The present invention relates to the identification of a novel allele of the RHD gene associated with a weak D phenotype and the kits and methods for detecting this allele.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: February 15, 2022
    Assignees: ETABLISSEMENT FRANCAIS DU SANG, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), NATIONAL INSTITUTE OF IMMUNOHAEMATOLOGY, UNIVERSITE DE BRETAGNE OCCIDENTALE (UBO)
    Inventors: Yann Fichou, Swati Kulkarni
  • Methods and devices for obtaining cellular and DNA material from human female reproductive system
    Patent number: 11230729
    Abstract: Efficient harvesting of cells, cell fragments, free nuclei, and DNA material from female reproductive system is made possible by processing gelatinous part of cervical mucus. Rinsing may be used to separate the gelatinous part of cervical mucus from the remainder of the cervical mucus sample.
    Type: Grant
    Filed: February 17, 2019
    Date of Patent: January 25, 2022
    Assignee: INANNA DIAGNOSTICS, INC
    Inventor: Maya Tevlin
  • RNA sequencing methods
    Patent number: 11220709
    Abstract: Described herein are methods for determining a sequence of a region of interest from an mRNA molecule. Sequenced polynucleotides can include a barcode region, a homopolymer region (e.g., a poly-A region), and a target region associated with the mRNA molecule. According to some methods, the barcode region omits the same base present in the homopolymer region. According to some methods, extension of the primer used for sequencing is stalled within the homopolymer region. According to some methods, sequencing flow cycles and the different barcode regions of the polynucleotides configured are such that the primer is extended to the end of the barcode region across the plurality of polynucleotides before being extended into the homopolymer region. According to some methods, two primers or a cleavable primer is used to separately sequence the barcode region and the target region.
    Type: Grant
    Filed: January 26, 2021
    Date of Patent: January 11, 2022
    Assignee: ULTIMA GENOMICS, INC.
    Inventors: Florian Oberstrass, Gilad Almogy