Patents Examined by Jennifer M. H. Tichy
  • Patent number: 11930822
    Abstract: Compositions comprising Methylobacterium with anti-fungal activity, methods for controlling plant pathogenic fungi, and methods of making the compositions are provided.
    Type: Grant
    Filed: March 4, 2022
    Date of Patent: March 19, 2024
    Assignee: NewLeaf Symbiotics, Inc.
    Inventors: Renèe Rioux, Charles Michael McFatrich, Kishore Nannapaneni
  • Patent number: 11921123
    Abstract: A quantitative detection method of rare earth doped calcium phosphate fluorescent nanoparticles (RE-nCaP) in organisms includes establishing a fluorescent intensity-concentration standard curve of rare earth ions, preparing samples to be tested and the blank control group into homogenate, performing centrifuging and testing the fluorescent intensity of supernatants, calculating the fluorescent intensity values per unit mass or volume of the samples and the blank control group, and performing significant difference analysis; if P is greater than or equal to 0.05, determining that the RE-nCaP content in the samples is 0, and if P is smaller than 0.05, testing the tissue extraction rate of RE-nCaP; and comprehensively considering the tissue extraction rate, the homogenate volume, the fluorescent intensity value per until mass or volume, the homogenate dilution ratio, and the doping amount to obtain the accurate content of the RE-nCaP in biological tissue samples.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: March 5, 2024
    Inventors: Yingchao Han, Qingguo Xing, Xinyu Wang
  • Patent number: 11920125
    Abstract: The disclosure provides a method of treating, preventing, and/or controlling plant diseases by applying the agricultural composition comprising a bacterial isolate belonging to Paenibacillus or Bacillus. Also, the disclosure provides a method of enhancing disease resistance of a plant seed by applying the agricultural composition to the plant seed, and an agricultural composition comprising the bacterial isolate.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: March 5, 2024
    Assignee: Tenfold Technologies, LLC
    Inventors: Shaohua Guan, Shashi Shankar Rajbanshi, Curtis Brian Hill
  • Patent number: 11913060
    Abstract: Methods and solutions are disclosed for the quantification of mixed-linkage beta-glucan in plant biomass samples. Improved alkaline pretreatment, enzymatic hydrolysis, and glucose measurement parameters are provided that increase the accuracy, precision, and sensitivity of mixed-linkage beta-glucan assays.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: February 27, 2024
    Assignee: Edeniq, Inc.
    Inventors: Prachand Shrestha, Denmark Antolin
  • Patent number: 11903979
    Abstract: The present invention relates to compositions comprising Lactobacillus plantarum 2830 (ECGC 13110402), or mutant strain or strains thereof, for use in the treatment or prevention of hypertension.
    Type: Grant
    Filed: July 20, 2022
    Date of Patent: February 20, 2024
    Inventor: Stephen Patrick O'Hara
  • Patent number: 11873220
    Abstract: According to the present invention, organic material is converted to biogas through anaerobic digestion and the biogas is purified to yield a combustible fluid feedstock comprising methane. A fuel production facility utilizes or arranges to utilize combustible fluid feedstock to generate renewable hydrogen that is used to hydrogenate crude oil derived hydrocarbons in a process to make transportation or heating fuel. The renewable hydrogen is combined with crude oil derived hydrocarbons that have been desulfurized under conditions to hydrogenate the liquid hydrocarbon with the renewable hydrogen or alternatively, the renewable hydrogen can be added to a reactor operated so as to simultaneously desulfurize and hydrogenate the hydrocarbons. The present invention enables a party to receive a renewable fuel credit for the transportation or heating fuel.
    Type: Grant
    Filed: April 5, 2021
    Date of Patent: January 16, 2024
    Assignee: Iogen Corporation
    Inventor: Brian Foody
  • Patent number: 11832611
    Abstract: Methods of controlling agricultural pests are disclosed. An aerated liquid mixture is formed from a composition containing a bacterial nutrient source, a nitrogen-containing compound, a phosphate-containing compound, a magnesium-containing compound, a buffer, a chitinase inducer, and at least one strain of bacteria that produces chitinase. The liquid mixture is administered to soil and plants, and acts as an organic biological pesticide.
    Type: Grant
    Filed: November 14, 2021
    Date of Patent: December 5, 2023
    Assignee: TLC PRODUCTS
    Inventor: John M. Wong
  • Patent number: 11828766
    Abstract: In some aspects, automated rapid antimicrobial susceptibility testing systems for performing a multi-assay testing sequence can include an automated incubation assembly having a nest assembly adapted to house at least one test panel having a plurality of wells for receiving a sample comprising microorganisms originating from a clinical sample, the incubation assembly facilitating incubation of one or more test panels in order to undergo the multi-assay testing sequence; a robotic handling assembly configured to accept one or more incoming test panels and move them to and from the incubation assembly for incubation between each assay of the multi-assay testing sequence; an automated liquid handling assembly configured to exchange one or more fluids in the plurality of wells of the test panels; and an optical assembly for interrogation and readout of each assay of the multi-assay testing sequence being performed in the plurality of wells.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: November 28, 2023
    Inventors: Aleksandar Vacic, Nathan Purmort, Eric Stern, Anna Passernig, Paul Otten, Randy Tragni, Ronan Hayes, Andriy Tsupryk, Bruce Richardson
  • Patent number: 11821016
    Abstract: An objective of the present invention is to provide a culturing method, by which Bacillus bacterial spores can be efficiently produced. The present invention provides a method for producing Bacillus bacterial spores, comprising culturing Bacillus bacteria in a liquid medium containing a sugar or a sugar-source raw material at a concentration between 50.1 g/L and 100 g/L at the start of culture, and then in the course of the culture, feeding a fed-batch medium containing a sugar or a sugar-source raw material and a nitrogen-containing compound, and having the weight ratio (C/N ratio) of carbon atoms to nitrogen atoms ranging from 5.5 to 13.5 to the liquid medium.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: November 21, 2023
    Assignee: SDS BIOTECH K.K.
    Inventor: Yuki Tsukagoshi
  • Patent number: 11801272
    Abstract: The present invention relates to Bacillus strains which improves health and performance of production animals. The invention further relates to compositions comprising the Bacillus strains.
    Type: Grant
    Filed: October 13, 2021
    Date of Patent: October 31, 2023
    Assignee: Novozymes A/S
    Inventors: Derrick Lewis, Marianne Thorup Cohn, Adam Nelson, Preben Nielsen
  • Patent number: 11795345
    Abstract: Processes disclosed are capable of converting biomass into high-crystallinity, hydrophobic cellulose. In some variations, the process includes fractionating biomass with an acid (such as sulfur dioxide), a solvent (such as ethanol), and water, to generate cellulose-rich solids and a liquid containing hemicellulose and lignin; and depositing lignin onto cellulose fibers to produce lignin-coated cellulose materials (such as dissolving pulp). The crystallinity of the cellulose material may be 80% or higher, translating into good reinforcing properties for composites. Optionally, sugars derived from amorphous cellulose and hemicellulose may be separately fermented, such as to monomers for various polymers. These polymers may be combined with the hydrophobic cellulose to form completely renewable composites.
    Type: Grant
    Filed: October 11, 2021
    Date of Patent: October 24, 2023
    Assignee: GranBio Intellectual Property Holdings, LLC
    Inventors: Kimberly Nelson, Theodora Retsina, Vesa Pylkkanen, Ryan O'Connor
  • Patent number: 11752180
    Abstract: The present invention provides an intestinal tract protective agent comprising a polyphosphoric acid or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: September 12, 2023
    Assignees: National University Corporation Asahikawa Medical University, Sapporo Holdings Limited
    Inventors: Yutaka Kohgo, Mikihiro Fujiya, Nobuhiro Ueno, Syuichi Segawa, Naoyuki Kobayashi
  • Patent number: 11723928
    Abstract: This document provides methods and materials for treating multiple system atrophy. For example, methods and materials for using autologous mesenchymal stem cells (e.g., adipose derived mesenchymal stem cells) to treat multiple system atrophy are provided.
    Type: Grant
    Filed: August 12, 2022
    Date of Patent: August 15, 2023
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Wolfgang Singer, Phillip Low
  • Patent number: 11717544
    Abstract: A method for growing probiotic organisms wherein the growth media includes prebiotics especially selected and prepared to be paired with the probiotic organisms being grown. The prebiotic formula is optimized to grow the desired probiotic organisms, as well as important byproducts of the growth process. Specialized freeze-drying buffers may also be paired with certain probiotic organisms for the freeze-drying process. Specific products may utilize selected probiotic organisms grown and supported with paired prebiotic formulas to promote and maintain physiological health in a subject.
    Type: Grant
    Filed: February 25, 2022
    Date of Patent: August 8, 2023
    Inventors: Shayne Morris, Michael Benson
  • Patent number: 11716995
    Abstract: A method for producing an antimicrobial agent is provided. The method includes co-fermenting at least one seed of Lepidium Sativum and at least one yeast in a growth media to produce a yeast lees co-fermented by-product. The yeast lees by-product is then applied to a growth medium and at least one cell of Ganoderma Lucidum as a liquid medium under controlled conditions to produce mycelium and the liquid medium is agitated. The liquid medium is then filtered to isolate and extract an antimicrobial agent.
    Type: Grant
    Filed: November 2, 2020
    Date of Patent: August 8, 2023
    Assignee: Active Micro Technologies, LLC
    Inventors: Durant Scholz, Tiffany Russell, Erica Segura, Anna Crovetto, Maureen Danaher, Monica Beltran, Parisa Mehrzadeh
  • Patent number: 11718821
    Abstract: A method for growing probiotic organisms wherein the growth media includes prebiotics especially selected and prepared to be paired with the probiotic organisms being grown. The prebiotic formula is optimized to grow the desired probiotic organisms, as well as important byproducts of the growth process. Specialized freeze-drying buffers may also be paired with certain probiotic organisms for the freeze-drying process.
    Type: Grant
    Filed: November 5, 2021
    Date of Patent: August 8, 2023
    Inventors: Shayne Morris, Michael Benson
  • Patent number: 11713479
    Abstract: A method for determining whether a test sample contains a phytopathogenic fungus, which includes (a) putting the test sample on a front surface of a substrate having a through hole; the substrate having a cellulose film on the back surface thereof; the through hole has a cross-sectional area of not less than 7.065 square micrometers and not more than 19.625 square micrometers; and the cellulose film has a thickness of not less than 0.5 micrometers and not more than 3.7 micrometers; (b) leaving the test sample at rest after the step (a); (c) irradiating the cellulose film with ultraviolet light after the step (b); (d) bringing a back surface of the cellulose film into contact with a fungus color reaction reagent after the step (c); and (e) determining that the test sample contains the phytopathogenic fungus, if a color is given to the fungus color reaction reagent.
    Type: Grant
    Filed: July 16, 2021
    Date of Patent: August 1, 2023
    Inventors: Yuki Kushida, Yoshitsugu Uriu, Yosifumi Kariatumari
  • Patent number: 11702680
    Abstract: Provided herein are methods for generating cellular biomass in continuous aerobic fermentation systems. The biomass yield, and the concentration of polyhydroxyalkanoate within the biomass, are each directed to advantageous levels by operating the continuous fermentation system under particular nutrient limitation conditions. Also provided are biomass produced using the provided methods, and animal feed compositions including the provided biomass.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: July 18, 2023
    Inventors: Alexander Brett Foster, Cristina Serrano Amatriain, Gary J. Smith, Paul Sheldon Pearlman, Mark Paul Taylor
  • Patent number: 11680278
    Abstract: Methods of and system for growing and maintaining an optimized/ideal active yeast solution in the yeast tank and fermenter tank during the fermentation filling cycle are provided. A new yeast stage tank is used between the yeast tank and the fermenter tank allowing yeast to rapidly produce a huge amount of active young yeast cells for a fermenter during the filling period. A measurable and useful controlling factor, % DT/% Yeast by weight ratio (or “food” to yeast ratio), is used (e.g., % DT=glucose), which offers information on the health status of the yeast. The controlling factor is used to control the status of the yeast throughout the entire process.
    Type: Grant
    Filed: July 12, 2022
    Date of Patent: June 20, 2023
    Assignee: Lee Tech LLC
    Inventor: Chie Ying Lee
  • Patent number: 11661586
    Abstract: Compositions comprising (i) lactate oxidase (LOX) and Catalase (CAT), preferably in a 1:1 molar ratio; or (ii) a fusion polypeptide comprising both LOX and CAT, e.g., LOXCAT, and methods of use thereof for reducing blood lactate levels, increasing blood pyruvate levels, and/or decreasing blood lactate/pyruvate ratio in a subject.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: May 30, 2023
    Assignee: The General Hospital Corporation
    Inventors: Vamsi K. Mootha, Xiaoyan Robert Bao, Anupam Patgiri