Abstract: Disclosed embodiments relate to apparatuses and methods for wound treatment. In some embodiments, a negative pressure source is incorporated into a wound dressing apparatus so that the wound dressing and the negative pressure source are part of an integral or integrated wound dressing structure that applies the wound dressing and the negative pressure source simultaneously to a patient's wound. The negative pressure source and/or electronic components may be positioned between a wound contact layer and a cover layer of the wound dressing. The negative pressure source and/or electronic components may be separated and/or partitioned from an absorbent area of the dressing. A switch may be integrated with the wound dressing to control operation of the wound dressing apparatus. A connector may be direct air from an outlet of the negative pressure source to the environment. A non-return valve may inhibit back flow of air into the wound dressing.

Abstract: Provided is an applicator for the dispensing of a powder such as a pharmaceutical powder, on a target location. Also, provided are methods of applying a powder on a surface using the applicator.

Abstract: Multi-dose ocular fluid delivery devices are provided. Aspects of the fluid delivery devices include a fluid package and an actuator. The fluid package includes a reservoir of an ophthalmic formulation, an aperture and a valve member for sealing the aperture when fluid is not being ejected therethrough. The actuator is configured to operate the valve member so as to at least reduce, if not prevent, ingress of outside materials or contaminants into the reservoir, such that the ophthalmic formulation present in the reservoir does not require a preservative (e.g., where a preservative-free ophthalmic formulation is present in the reservoir). Also provided are methods of using the devices in fluid delivery applications, as well as a kit that includes components of the devices.

Abstract: An extracorporeal blood circulation system monitors blood level in a reservoir which temporarily stores the blood. A memory storage unit stores blood pressure measurements from a pressure sensor monitoring a blood pressure within a tube unit conveying blood from the reservoir relative to atmosphere. A processing unit that detects a height of a top surface of the blood stored in the reservoir based on changes in the blood pressure measurements and a conservation of mechanical energy of a blood flow inside the tube unit. A notification is generated if an abnormality is detected in the height of the blood in the reservoir.

Abstract: Porous formulation storage cushion, formulation delivery systems including porous formulation storage cushions, and methods of additively manufacturing a porous formulation storage cushions are described. In an embodiment, the porous formulation storage cushion defines a plurality of pores configured to absorb a formulation, such as through wicking the formulation through capillary action. In an embodiment, the plurality of pores is configured to define a capillary force gradient along a length of the porous formulation storage cushion.

Abstract: A computer-implemented method comprises providing a fluid circuit comprising fluid pathways configured to mount and associate with a durable processing device comprising a pressure sensor in communication with a controller and a fluid pathway. A container is connected to the pressure sensor and may receive a volume of fluid. A change in pressure values between a first and second time is measured from when the volume of fluid is not in communication with the pressure sensor to when the volume of fluid is in communication with the pressure sensor, the volume of fluid within the container or a presence or absence of a fluid connection to the fluid pathway based on the change in pressure values is determined, and a response action is executed if the volume of fluid within the container is not within an authorized volume range for the time period, or if a fluid connection is unauthorized.

Abstract: An extracorporeal circulation management device pumps blood in synchronization with heartbeats of a patient based on measurements of blood flow. Maximum and minimum blood flow measurement samples are compared with upper and lower threshold values to identify candidate timing for a systolic phase and diastolic phase of the heartbeat. During pulsatile pumping of the blood using the candidate timing, differences in the pulsatile flow measurements are determined. Based on the size of the difference, a final correction may be made to identification of the systolic and diastolic phases, and the corrected phase information is used to start and stop the motor unit.

Abstract: Provided is a blood component sampling cassette which can be efficiently manufactured at low cost compared to a conventional cassette, a method for manufacturing the blood component sampling cassette, a blood sampling circuit set and a blood component sampling system. The blood component sampling cassette includes a cassette main body having a plurality of flow paths including an introduction line, a blood component transfer line and a retransfusion line. The cassette main body includes a first sheet and a second sheet which are formed of a soft material compatible with autoclave sterilization. The first sheet and the second sheet are overlaid in a thickness direction and bonded to each other. A plurality of flow paths is formed between the first sheet and the second sheet.

Abstract: A negative pressure wound closure system and methods for using such a system are described. Preferred embodiments of the invention facilitate closure of the wound by preferentially contracting to provide for movement of the tissue. Some embodiments may include wound closure devices built from smaller units that are modular, assemble-able and/or customizable.

Abstract: Embodiments of apparatuses, systems, methods for monitoring wound pH are disclosed. In some embodiments, a wound dressing includes one or more optical sensors configured to measure a change in color of a pH-sensitive adhesive that changes color in response to changes in wound exudate pH. In some embodiments, the wound dressing may further comprise hydrophilic channels that direct wound exudate to a pH-sensitive material over the optical sensors. Such dressings may also be used in combination with a negative pressure wound therapy system.

Abstract: Disclosed embodiments relate to apparatuses and methods for wound treatment. In some embodiments, a wound dressing apparatus can comprise a wound contact layer, a spacer layer, an absorbent layer positioned on the spacer layer, an electronics unit comprising a negative pressure source and/or electronic components, wherein the absorbent layer comprises a recess configured to receive the electronics unit and the absorbent layer is configured to be in fluid communication with the electronics unit, and a cover layer configured to cover and form a seal over the wound contact layer, the spacer layer, the absorbent layer, and the electronics unit.

Abstract: A wound treatment system includes a housing. A processor is located in the housing. A pressure monitoring system is coupled to the processor. A power delivery system is located in the housing and coupled to the processor. An oxygen concentrator is located in the housing and coupled to the power delivery system. The oxygen concentrator includes a plurality of oxygen outlets. The processor is configured to receive pressure information from the pressure monitoring system that is indicative of a pressure in a restricted airflow enclosure provided by a dressing and located adjacent a wound site; and use the pressure information to control the power provided from the power delivery system to the oxygen concentrator in order to control an oxygen flow created by the oxygen concentrator and provided through one of the plurality of oxygen outlets to the restricted airflow enclosure.

Abstract: (Object) To prevent a high compression portion from being defectively formed and also a top sheet from being torn. (Means of Achieving the Object) A sanitary napkin (1) in which a low compression portion (15) and a high compression portion (16, 17, 18) are formed on a bottom surface of a compressed groove (10) that is recessed from a skin contact surface side.

Abstract: Methods, apparatus, and device, such as a blood bag envelope, that protects a blood bag during storage and/or transport. The blood bag envelope holds a blood bag or a metal cassette that contains the blood bag. The envelope includes multiple panels. The multiple panels include a top panel, a first edge panel, a second edge panel, a front panel and a bottom panel. The multiple panels are configured to fold to form the enclosure to hold the blood bag. The envelope includes a first fastening device connected to an inner surface of the top panel. The envelope includes a suspension device that is suspended from the first fastening device. The suspension device is configured to suspend the blood bag within the enclosure when the multiple panels are folded to form the enclosure.

Abstract: A backflow and leakage preventing menstrual cup for collecting menstrual discharge is disclosed. The menstrual cup has a safety feature that prevents backflow of menstrual blood back into vagina and uterus, which minimizes contact with the collected menstrual blood and prevents the risk of infection and toxic shock syndrome (TSS) to the user. This safety feature also stops accidental leakage during use and prevents spillage of menstrual blood when the cup is removed by user. The cup is designed to be easily and quickly emptied.

Abstract: An apparatus and system for treating a wound having a cavity is disclosed. The apparatus has a scaffold including a scaffold lamina and a tissue lamina wherein the scaffold lamina forms a laminate in fluid communication with the tissue lamina. The laminate is rolled into a generally cylindrical shape having two end surfaces. The apparatus further includes a manifold having a port for coupling to a source of reduced pressure and that is positioned in fluid communication with the scaffold to provide reduced pressure to the scaffold lamina and the wound. A method for treating a wound having a cavity is also disclosed and includes positioning a scaffold lamina adjacent a tissue lamina to form a laminate in fluid communication with the tissue lamina, rolling the laminate into a generally cylindrical shape having two end surfaces, and positioning the scaffold within the cavity of the wound.

Abstract: Embodiments of negative pressure wound therapy systems and methods for operating the systems are disclosed. In some embodiments, a system includes a negative pressure source, a wound dressing configured to be positioned over a wound, and optionally a canister configured to store fluid aspirated from the wound. The negative pressure source, wound dressing, and canister (when present) can be fluidically connected to facilitate delivery of negative pressure to the wound. The system can be configured to automatically detect whether the canister is positioned in the fluid flow path between the negative pressure source and the dressing while negative pressure source provides negative pressure to the wound dressing. Operation of the system can be adjusted based on whether presence of the canister has been detected. For example, a value of an operational parameter can be set to indicate that the canister is present.

Abstract: The present invention relates to a negative pressure wound closure system and methods for using such a system. Preferred embodiments of the invention facilitate closure of the wound by preferentially contracting to provide for movement of the tissue.

Abstract: A catheter is disclosed that includes an elongated shaft, an insertable end formed in or connected to one end of the elongated shaft, and a discharge end formed in or connected to the opposite end of the elongated shaft. Further, the catheter includes an insertion aid that at least partly encircles the discharge end, and is integrally and releasably connected to the discharge end. The catheter can be easily produced, and at the same time, the insertion aid may easily be removed for use as an insertion aid when using the catheter.

Abstract: A foldable urinary catheter is provided for draining the human bladder defining an internal flow path for urine, with a catheter tube for insertion into the urethra, the catheter tube having at least one hinge which can enable the catheter into a folded, compact storage condition and an unfolded, straight ready-for-use condition as well as to a foldable urinary catheter kit. A foldable urinary catheter and a foldable urinary catheter kit are provided which are very small and compact in a transport or storage condition and which provide a long insertable length of the catheter tube. The hinge in the catheter tube is provided in the insertable length of the catheter tube and is configured for stabilizing the ready-for-use condition. The kit includes the foldable urinary catheter and a catheter package which tightly surrounds the folded catheter.