Abstract: Included are embodiments of an angled cartridge assembly for modifying a treating surface. These embodiments may include a reservoir for storing a treatment composition, the treatment composition for being applied to the treating surface. Embodiments may also include a body portion that is coupled to the reservoir, where the body portion comprises a base surface and a dispensing surface, where the dispensing surface is disposed opposite the base surface on the angled cartridge assembly, and where the dispensing surface is disposed in a nonparallel configuration relative to the base surface.

Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysis fluid circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid; a control unit (12) is configured for determining or receiving a proposed value (Condprop) of a conductivity for the dialysis fluid in the dialysis supply line (8) and to determine a set value (Condset) for the conductivity in the dialysis fluid as a function of the proposed value (Condprop) and as a function of at least one of a second parameter (UF volume/W; WL/W) indicative of a patient fluid overload and a third parameter (gconc) chosen in the group including: a glucose concentration in the patient and a concentration-related parameter of at least glucose in the patient.

Abstract: Described herein are devices and methods for vascular access via the tributaries. A single lumen catheter, with a bidirectional valve at the tip is disclosed. Flow is out the longitudinal tip of the catheter and not the sides. The two-way valve will act passively but has low opening and closing pressures. A method utilizing endo-to-side port placement of said catheter in vasculature is disclosed. Anastomosis methods are described using said catheter.

Abstract: A self-supporting applicator comprises a first structural element which is self-supporting and has a shape determined according to a target structure, the applicator further comprises an active agent.

Abstract: A BAK removal device is constructed as a plug of microparticles of a hydrophilic polymeric gel that displays a hydraulic permeability greater than 0.01 Da. The polymer hydrophilic polymeric gel comprises poly(2-hydroxyethyl methacrylate) (pHEMA). The particles are 2 to 100 ?m and the plug has a surface area of 30 mm2 to 2 mm2 and a length of 2 mm to 25 mm and wherein the microparticles of a hydrophilic polymeric gel has a pore radius of 3 to 60 ?m.

Abstract: Devices, systems, methods, and kits for treating cutaneous diseases, such as warts, with a cantharidin formulation are generally described. The cantharidin formulations, described herein, may have many advantages over traditional cantharidin formulations, including removal of highly volatile and corrosive solvents, improved safety, and improved compatibility with common plastics for ease of delivery. The devices, systems, methods, and kits can be used for the precise application of the cantharidin formulation for the treatment of cutaneous diseases and other topical indications. Treatment of cutaneous diseases with cantharidin, using the devices, systems, methods, and/or kits may have many advantages over traditional therapies, including high single application efficacy, lack of scaring, and a mild pain profile.

Abstract: An ocular implant adapted to be disposed within Schlemm's canal of a human eye with a body extending along a curved longitudinal central axis in a curvature plane, a first strut on one side of the implant and a second strut on an opposite side of the implant, the circumferential extent of the first strut with respect to the plane of curvature being greater than the circumferential extent of the second strut with respect to the plane of curvature. The invention also includes methods of using the implant.

Abstract: An embodiment includes a wound dressing comprising: a shape memory polymer (SMP) foam, including open cells, having first and second states; and a hydrogel (HG) included within the cells; wherein (a) in a first position a composite, including the SMP foam and the HG, is configured to be located proximate a hemorrhagic tissue with the SMP foam in the first state; (b) in a second position the composite is configured to be expanded to the second state against the hemorrhagic tissue when the SMP foam is plasticized at 37° C. depressing a glass transition temperature (Tg) of the SMP foam to below 25° C. Other embodiments are described herein.

Abstract: An oxygenator unit adapted for use in an extracorporeal blood treatment device. The oxygenator unit includes an oxygenator having a gas inlet and a supply line for conducting a gas provided at the gas inlet, the supply line being connectable to a source of a pressurized gas containing oxygen, wherein the oxygenator unit further includes a pressure relief valve provided in the supply line upstream of the oxygenator, the pressure relief valve adapted to release pressure exceeding a predetermined pressure value from the supply line, thereby preventing a critical overpressure in the oxygenator.

Abstract: The present invention is a device for holding an ophthalmic bottle of drops and instilling them in a patient's eye. The device rests on the boney lower orbital ridge for stability and correct delivery.

Abstract: Device for packaging and dispensing drops of a substance for ophthalmic use, generally fluid, semi-fluid or in suspension, emulsion or oily solution including a dispensing accessory with a first valve made of an elastomer material that allows the substance to pass through when the dispensing accessory is stressed, without allowing outside air to pass through in the opposite direction when the dispensing accessory is relaxed, characterized in that the first valve is covered by a layer of Parylene.

Abstract: Systems, apparatuses, and methods for instilling fluid to a tissue site in a negative-pressure therapy environment are described. Illustrative embodiments may include a pneumatically-actuated instillation pump that can draw a solution from a solution source during a negative-pressure interval, and instill the solution to a dressing during a venting interval. A pneumatic actuator may be mechanically coupled to a disposable distribution system that can provide a fluid path between the solution source and a distribution component. A bacterial filter may be disposed in the fluid path between the actuator and the distribution component to prevent contamination of the actuator during operation. The distribution system may be separated from the actuator and disposed of after operation, and the actuator may be re-used.

Abstract: A packaged closed intermittent urinary catheter system equipped with a dispensing system and method of dispensing a packaged catheter using the dispensing system. The dispensing system is a pair of separately translatable movement control devices, each operably engaging the catheter for permitting unidirectional movement of the catheter in a first axial direction relative to the movement control devices. The movement control devices may be mounted to a hand-grippable assembly with a sliding or pivoting movable member reciprocal to a base member. Alternatively, the movement control devices are mounted to a coupling member and a spring member biases them apart.

Abstract: The present invention provides a sanitary pad including an upper sheet made of pure organic cotton through which a liquid is permeable, a first absorbing sheet disposed below the upper sheet and made of pure organic cotton configured to absorb the liquid, a second absorbing sheet disposed below the first absorbing sheet and made of natural compressed pulp configured to absorb the liquid, and a waterproof sheet disposed below the second absorbing sheet and having air permeability.

Abstract: Various systems and methods are provided for reducing pressure at an outflow of a duct such as the thoracic duct or the lymphatic duct. A catheter system can include a catheter shaft configured to be at least partially implantable within a patient's vein, a flexible membrane attached to the catheter shaft, the flexible membrane being a collapsible, tube-like member having a lumen extending therethrough, and a single selectively deployable restriction member formed over a portion of the flexible membrane at substantially a midpoint between a proximal end of the flexible membrane and a distal end of the flexible membrane, the restriction member being configured to control a size of the lumen so as to direct a controlled volume of fluid from an upstream side of the restriction member to a downstream side the restriction member.

Abstract: Menstrual cups and methods of use are described herein. An example menstrual cup may include a rim having at least one lip that extends about the rim and a receptacle defining a textured pattern. The textured pattern may include various lines and/or shapes. An example menstrual cup may be comprised of silicone or a similar material and can be worn during sexual intercourse.

Abstract: Menstrual cups and methods of use are described herein. An example menstrual cup may include a rim having at least one lip that extends about the rim and a receptacle defining a textured pattern. The textured pattern may include various lines and/or shapes. An example menstrual cup may be comprised of silicone or a similar material and can be worn during sexual intercourse.

Abstract: Fluid delivery devices and methods are described, where the device may comprise a piezoelectric actuator operatively coupled to an ampoule with fluid, under a preloading force. The ampoule may comprise a thin-walled thermoplastic package which includes one or more apertures positioned on the wall of the ampoule. The piezoelectric actuator may be configured to clamp at least partially around the circumference of the ampoule and apply oscillations to its wall. The oscillations, typically in ultrasonic frequency, produce cycles of acoustic pressure in the fluid, leading to ejection of the fluid droplets or streams from the apertures.

Abstract: A purpose is to enable partial replacement of an indwelling urethral catheter. A unit for a balloon catheter according to the present invention includes a urethral catheter tube (13) provided with a first urethral catheterization passage (14), a branch tube (11) provided with a first passage (12) adapted to allow passage of a liquid used to inflate or deflate a balloon (54), and a connecting tube (30) configured to be connected at one end to the first urethral catheterization passage (14) or the first passage (12).

Abstract: A fluid-absorbent article having an upper liquid-pervious layer, a lower liquid-impervious layer, a fluid-absorbent core between the layer and the layer, containing from 0 to 20% by weight fibrous material and from 80 to 100% by weight of a water-absorbent polymer material, based on the sum of water-absorbent polymer material and fibrous material. The fluid absorbent article has a first intake time of 15 seconds or less by the hanging U-shape test (HUS).