Patents Examined by Jill Warden
  • Patent number: 11372012
    Abstract: A dispensing robot of an assay robot system includes a first contact surface oriented in a downward direction or an obliquely downward direction in a vertical direction and dispenses when the dispensing robot operates a pipette that allows a tip to be attached to a lower end of the pipette and the attached tip to be detached by pressing a tip ejector, the dispensing robot comprising: a robot arm having a hand to hold a pipette holding piece attached thereto; and a controller controls the robot arm such that the robot arm holds the pipette with the tip attached thereto by causing the hand to hold the pipette holding piece and that the robot arm is elevated and the tip ejector is pressed by bringing an upper end portion of the tip ejector of the held pipette into contact with the first contact surface from the downward direction.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: June 28, 2022
    Inventors: Yukio Iwasaki, Satoshi Ouchi, Eiji Mitsui, Junichi Matsuoka, Hiroya Kirimura, Yukihiko Kitano
  • Patent number: 11366129
    Abstract: An automatic analyzer includes a plurality of storage container holding units, a dispensing container holding unit, a plurality of dispensing devices, a dispensing abnormality detector, and a drive control unit. The plurality of dispensing devices each include a dispensing probe. The dispensing abnormality detector is provided in each dispensing device. The drive control unit is configured to control driving of each dispensing device based on a detection result of the dispensing abnormality detector. If a dispensing device in which an abnormality is detected is a first dispensing device, the drive control unit is configured to cause a dispensing process of a cycle in which the abnormality is detected to be performed again. If the dispensing device in which the abnormality is detected is not the first dispensing device, the drive control unit is configured to end the dispensing process of the cycle and start the next cycle.
    Type: Grant
    Filed: May 13, 2019
    Date of Patent: June 21, 2022
    Assignee: JEOL Ltd.
    Inventors: Makoto Asakura, Chikashi Nakai
  • Patent number: 11366128
    Abstract: A biological analysis system comprising at least one inlet and one outlet, at least two biological analysis devices connected to one another by a conveyor defining a closed circuit, each biological analysis device comprising a region for the exchange of tube holding racks with the conveyor. The conveyor and the at least one inlet of the biological analysis system comprise a reader of an identifier of a tube holding rack which reader is designed to communicate an identifier it has read to a controller of the biological analysis system, which controller is designed to apply a specific treatment to a tube holding rack identified by the reader of the conveyor and the identifier of which has not previously been read by the reader of the at least one inlet of the biological analysis system.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: June 21, 2022
    Assignee: HORIBA ABX SAS
    Inventors: Florent Beauducel, Philippe Benezeth, Thibault Cres
  • Patent number: 11366131
    Abstract: Embodiments are directed to transferring and opening reagent containers for use in a clinical analyzer in an in vitro diagnostics (IVD) environment. Contents of a reagent container may be automatically recorded, and the container is positioned and opened, making available its contents to a transfer probe. A set of mechanical fingers open and close relative to one another, to release and grip the reagent container on opposite sides thereof for transferring the container. Once the container is positioned, the mechanical fingers raise and are positioned above a seal concealing the contents of the reagent container. The fingers are configured to close together and travel in a downward trajectory to pierce the seal. The reagent container is originally presented as an un-opened package to prevent spillage and to control reagent life expectancy. According to an embodiment, a method of performing a cycle unload, transfer, and load, without operator intervention, is provided.
    Type: Grant
    Filed: June 22, 2017
    Date of Patent: June 21, 2022
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Peter L. Gebrian, Joseph E. Brennan, Ronald G. Barlow, William E. Hudson, William H. Reigle, Jr.
  • Patent number: 11358140
    Abstract: An cartridge is combined with a smart device which is capable of communicating with a network to perform a portable, fast, field assay of a small sample biological analyte. A closed microfluidic circuit for mixes the analyte with a buffer with functionalized magnetic beads capable of being specifically combined with the analyte. A detector communicates with the microfluidic circuit in which the mixed analyte, buffer and combined functionalized magnetic beads are sensed. A microcontroller is coupled to detector for controlling the detector and for data processing an output assay signal from the detector. A user interface communicates with the microcontroller for providing user input and for providing user output through the smart device to the network.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: June 14, 2022
    Assignee: Autonomous Medical Devices Inc.
    Inventors: Josh Yehoshua Shachar, Sam Gurley, Aaron Cipriano, Peter Yin, Rob Purnell, Marc Rocklinger, Ming Petrullo, Stelica Stelea, Marlon S. Thomas
  • Patent number: 11346851
    Abstract: Disclosed are high-throughput vessel sorting systems and methods of sorting sample vessels, such as samples stored in test tubes. A system for sorting a plurality of individual vessels that each contains a sample is disclosed.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: May 31, 2022
    Inventors: David Wilson, Jay Krajewski, Kevin Meyer
  • Patent number: 11344879
    Abstract: Provided herein is a semen processing device. The device is a collection cup with a top portion encompassing a collection cavity into which the semen sample is deposited and a bottom portion encompassing a processing chamber and containing the processing unit for the collected semen. A flow control valve or a serpentine channel may be disposed as part of the processing unit to regulate the flow rate of semen from the collection cavity into the processing unit. A harvesting dock is disposed through the surface of the bottom portion. The semen flows from the collection cavity into the processing unit and is harvested through the harvesting dock.
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: May 31, 2022
    Inventors: Dmitri Dozortsev, Michael Allon
  • Patent number: 11340241
    Abstract: An automated analyzer capable of continuously performing supply of consumables is realized while continuing measurement is performed, by a simple and small amount of mechanism. An automated analyzer includes a unit that executes processing necessary for sample analysis; a consumable supply unit that supplies consumables necessary for the sample analysis to the unit; and a control device that controls operations of the unit and the consumable supply unit, in which the consumable supply unit includes a consumable container holding portion that holds a consumable storage container in which consumables is aligned and accommodated, a preliminary storage portion that temporarily holds the consumables taken out from the consumable storage container, and a transport mechanism that transports the consumables to the unit, and in which the control device transports and stores at least a portion of the consumables taken out from the consumable storage container in the preliminary storage portion.
    Type: Grant
    Filed: January 24, 2018
    Date of Patent: May 24, 2022
    Inventors: Shunsuke Sasaki, Takenori Okusa, Yoshihiro Yamashita, Hiroki Fujita, Kenta Imai, Toshiharu Suzuki
  • Patent number: 11340242
    Abstract: Provided are a quality control method, a quality control system, a management apparatus, an analyzer, and a quality control abnormality determination method in which measurement results of both a quality control substance and a specimen are sufficiently utilized to improve the quality of quality control. The quality control method used in a management apparatus which is connected via a network to an analyzer installed in each of a plurality of facilities includes obtaining, from an analyzer in each facility via a network, first quality control information obtained by measuring an artificially generated quality control substance, and second quality control information obtained by measuring a plurality of specimens by the analyzer in each facility; and outputting information concerning quality control of an analyzer in at least one facility, based on the obtained first quality control information and second quality control information.
    Type: Grant
    Filed: July 29, 2019
    Date of Patent: May 24, 2022
    Inventors: Keiji Fujimoto, Kazuhiko Matsuoka, Yasushi Hasui
  • Patent number: 11338297
    Abstract: This disclosure provides a sample rack, a sample access kit and a sample access system. The sample rack comprises: a rack body for placing a sample container; a position collector configured to acquire a position of the sample container placed on the rack body; and a communicator configured to transmit identification information of the sample rack and the acquired position of the sample container on the rack body. The sample access kit comprises the above-described sample rack and a sample container having an identification disposed thereon. The sample access system comprises the above-described sample access kit and a mobile terminal.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: May 24, 2022
    Assignee: BOE Technology Group Co., Ltd.
    Inventor: Maoyong Fu
  • Patent number: 11333587
    Abstract: An analytic plate or other substrate having a permanent etchable, laserable, and/or developable marking surface coating (referred to herein as an “etchable coating” or as a “developable coating”) that is present on at least a portion of any side or surface thereof and is used to deposit a permanent indicium thereon, and a method of using the analytic plate or substrate.
    Type: Grant
    Filed: November 19, 2019
    Date of Patent: May 17, 2022
    Inventor: Lee H. Angros
  • Patent number: 11327023
    Abstract: A system, method, and apparatus for sensing analytes comprises assembling a sensor of at least one polymer and at least one fluorophore by mixing the polymer with the fluorophore, exposing the sensor to an analyte, and identifying the presence of the analyte according to a change in fluorescence of the sensor. The sensor can comprise a non-covalent complex of the at least one fluorophore and the at least one polymer. The at least one polymer can comprise a polymer capable of binding a metal ion. The at least one polymer is capable of binding a metal ion comprising an imidazole-containing polymer such as an N-vinylimidazole homo polymer and/or an N-vinylimidazole co-polymer.
    Type: Grant
    Filed: March 26, 2020
    Date of Patent: May 10, 2022
    Inventor: Gregory Fernandes
  • Patent number: 11319572
    Abstract: A device (1; 2; 3; 4; 5) is provided for carrying out an integrity test on a sample of disposable components. The device has a medium chamber (10) with an inner chamber (11) that is bounded to the outside, for the purpose of receiving a culture medium. The device also has a sample holder (20) in which the sample (100) can be arranged in such a way that the sample (100) at least partially bounds the medium chamber (10) to the outside. The medium chamber (10) has a vent line (19) that is arranged on a side of the medium chamber (10) facing away from the sample holder (20).
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: May 3, 2022
    Inventors: Martin Dahlberg, Isabelle Gay, Marie Christine Menier, Nelly Montenay
  • Patent number: 11311874
    Abstract: Embodiments of substrate-based devices disclosed herein comprise a polymeric substrate with a hydrophobic polymer coating that defines wells or openings on the polymeric substrate and/or serves as an adhesive agent between stacked substrates of the device. Also disclosed herein are embodiments of plate frames that can be used to align and hold well plate devices described herein. Methods of fabricating the disclosed devices also are described.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: April 26, 2022
    Assignee: Oregon Slate University
    Inventors: Gayan C. Bandara, Christopher A. Heist, Sumate Pengpumkiat, Vincent T. Remcho
  • Patent number: 11311886
    Abstract: The invention relates to a holding apparatus (100) for sample carriers (200) for use in cryomicroscopy, encompassing: a body having at least one sample carrier receptacle that comprises at least one sample carrier support surface against which at least one sample carrier (200) is abuttable; at least one first sample carrier holding means (121); and at least one second sample carrier holding means (131) that is configured to impinge upon the sample carrier (200) with force against the first sample carrier holding means (121); and to an arrangement having a manipulation container and such a holding apparatus (100), and to methods for introducing and withdrawing a sample carrier (200).
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: April 26, 2022
    Inventors: Reinhard Lihl, Leander Gaechter, Saskia Mimietz-Oeckler
  • Patent number: 11300563
    Abstract: According to one embodiment of the present application, a biosensor, the biosensor comprising: a reaction part including a magnetic nanoparticle complex, a first electrode, and a second electrode; and a sample introduction part forming a passage so that a sample can be introduced into the reaction part from an outside of the biosensor; wherein the magnetic nanoparticle complex includes a first capturing substance for capturing a first target substance, a magnetic nanoparticle, and a reaction substance that performs at least one of an oxidation reaction and a reduction reaction, wherein the magnetic nanoparticle complex has is magnetic in the reaction part, and has a property that mobility can be changed according to a change in a condition of the reaction part, wherein the first electrode, a second capturing substance for capturing a second target substance is fixed, wherein the second electrode is an electrode different from the first electrode, and characterized in that at least one of the first target subs
    Type: Grant
    Filed: September 2, 2020
    Date of Patent: April 12, 2022
    Assignee: BBB Inc.
    Inventors: Hyundoo Hwang, Jaekyu Choi
  • Patent number: 11300578
    Abstract: In one embodiment, a diagnostic system includes an instrument coupled to a client device and having at least one sample processing bay. The diagnostic system has a software architecture including instrument software (ISW) associated with the instrument. The ISW receives an assay definition file (ADF) that has a control file and an assay analysis module (AAM) file. The processing bay prepares and senses the sample according to parameters in the OPUS file and then generates sensor scan data. The diagnostic system then analyzes the sensor scan data and prepares a report according to the AAM file.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: April 12, 2022
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Michael Thomas Nguyen, Sean Ford, Nikolas James Hansen
  • Patent number: 11293933
    Abstract: A fully-automatic feces analyzer includes an automatic controller; at least one sample box for containing a feces sample; and a sample box support. A dilution and stirring unit is provided for adding diluent into the feces sample and stirring to obtain feces sample liquid. The analyzer has a physical detection unit for performing a physical detection on the feces sample liquid and at least one chemical detection unit for performing a chemical detection on the feces sample liquid. Each chemical detection unit includes a driving roller and a driven roller, a reagent strip roll wound on the driven roller, an end portion of the reagent strip roll fixed on the driving roller.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: April 5, 2022
    Inventor: Xianglong Li
  • Patent number: 11287365
    Abstract: A cuvette comprising: a main body having a sample chamber formed therein, the sample chamber communicating with the exterior of the cuvette by an opening formed in the exterior of the main body, wherein the sample chamber comprises a first sample chamber and a second sample chamber, the first sample chamber being in fluid communication with the opening, and the second sample chamber having a first end which is in fluid communication with the first sample chamber, and a second, closed end, the second sample chamber being in fluid communication with the exterior of the cuvette only through the first chamber, the first chamber having a width which is greater than that of the second chamber, and further wherein the greatest width of the opening is greater than or equal to the greatest width of the first sample chamber, the greatest width of the first sample chamber is greater than or equal to the greatest width of the second sample chamber, and the width of the sample chamber, passing from the opening to the clos
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: March 29, 2022
    Assignee: Entia Limited
    Inventors: Millie Clive-Smith, Toby Basey-Fisher
  • Patent number: 11285487
    Abstract: Apparatuses and associated methods of manufacturing are described that provide a tip resistant optical testing instrument configured to rest on a surface. The optical testing instrument includes a shell defining a cavity for receiving a sample tube. The shell includes a bottom shell surface, wherein the bottom shell surface defines at least one support element, wherein the at least one support element is configured to engage the surface to support the optical testing instrument in a testing position, and a translational surface configured to engage the surface to support the optical testing instrument in an angled position. In an instance in which the optical testing instrument tilts from the testing position to the angled position, the translational surface is configured to engage the surface contacting the translational surface to prevent the optical testing instrument from tipping further and allow the optical testing instrument to return to the testing position.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: March 29, 2022
    Assignee: bioMerieux, Inc.
    Inventors: Jack R. Hoffmann, Jr., Gregory R. Maes