Patents Examined by Jill Warden
-
Patent number: 10646873Abstract: A multi-well plate lid includes a well-side surface to cover a plurality of wells of a multi-well plate. The well-side surface includes two or more regions with different adhesive strengths to the multi-well plate.Type: GrantFiled: December 19, 2017Date of Patent: May 12, 2020Assignee: Ricoh Company, Ltd.Inventors: Hiroki Somada, Satoshi Izumi, Takahiko Matsumoto, Daisuke Takagi
-
Patent number: 10641751Abstract: An ion exchange chromatographic packing material is described that includes support resin particles and a copolymer grafted to the support resin particles. The copolymer includes polymerized functional monomers such as a first ion exchange group monomer and a second ion exchange group monomer. At a first pH, the first ion exchange group monomer is configured to have a first charge at a first pH, and the second ion exchange group monomer is configured to have a net neutral charge. At a second pH, the first ion exchange group monomer is configured to have the first charge at a second pH, and the second ion exchange group monomer is configured to have a second charge at the second pH where the first charge and second charge both have a same polarity.Type: GrantFiled: June 19, 2015Date of Patent: May 5, 2020Assignee: Dionex CorporationInventors: Manikandan Jayaraman, Christopher A. Pohl, Charanjit Saini
-
Patent number: 10639625Abstract: A pipette tip includes a body and projections. In the body, a flow passage in which liquid from the syringe flows and an ejection opening that ejects the liquid, which has flowed through the flow passage, to the outside are formed. The ejection opening is formed in a distal end portion. The projections are provided on the distal end portion and protrude from a region around the ejection opening in the ejection direction of liquid. The projections are partially disposed around the central axis of the body. Even in a case where a residual droplet adheres to the ejection opening, the residual droplet does not adhere to an injection opening of a sample container, because the projections guard a region around the residual droplet.Type: GrantFiled: March 23, 2018Date of Patent: May 5, 2020Assignee: FUJIFILM CorporationInventors: Toshiaki Kuniyasu, Toshihito Kimura, Tomonori Nishio, Kazuteru Nishijima
-
Patent number: 10638748Abstract: A vial is described herein that comprises a tubular body which comprises an opened end, a closed end, and a cavity, wherein the opened end is located at one end of the tubular body and the closed end is located at an opposing end of the tubular body. The tubular body further comprises a tear line located therein, wherein the tear line extends across at least a portion of one side of the tubular body, across the closed end, and across at least a portion of another side of the tubular body. In addition, the tubular body further comprises two flanges extending from the closed end, wherein the two flanges are configured to separate from one another outwardly from the tubular body and apply a force to break-open at least a portion of the tear line to open at least the closed end of the tubular body.Type: GrantFiled: December 15, 2016Date of Patent: May 5, 2020Assignee: Corning IncorporatedInventor: Michael Kurt Schaefer
-
Patent number: 10639608Abstract: A system, apparatus, and method for transferring chemical solutions and synthesizing a tracer. For transferring chemical solutions, the system comprises a primary container; a secondary container; a first line in communication with the primary container and the secondary container. The first line facilitates the flow of gas and/or liquid between the primary container and the secondary container. A valve located upstream of the secondary container and downstream of the primary container regulates flow within the first line; a second line in communication with the secondary container. For synthesizing a tracer, the system includes a source of a solution having a radionuclide. A first container has a tracer precursor and is in communication with the source of solution.Type: GrantFiled: April 12, 2012Date of Patent: May 5, 2020Assignee: Siemens Medical Solutions USA, Inc.Inventors: Umesh B. Gangadharmath, Joseph C. Walsh, Hartmuth C. Kolb, Ricardo Rodriguez, Arkadij M. Elizarov, Carroll Edward Ball
-
Patent number: 10634584Abstract: A microscopic collection device, method for collecting a microscopic sample from a target surface, and the work stand for holding the microscopic collection device are provided. The microscopic collection device includes a holding element comprising a handle at one end and a collection platform connected to the holding element at a second end. The collection platform includes a collection surface on which the microscopic sample is deposited when the microscopic collection device comes into contact with the target surface. A tape is inserted through a slit and wrapped around the collection platform. The work stand includes a slit capable of holding the microscopic collection device such that the collection platform is perpendicular to the top surface of the work stand. A microscopic sample, collected using the microscopic collection device, is not only collected from the target surface but is also concentrated onto the collection face of the tape.Type: GrantFiled: December 17, 2015Date of Patent: April 28, 2020Assignee: ROKU, INC.Inventors: Michael Heath Farris, Kevin Robert Gemp, David Masters
-
Patent number: 10634590Abstract: Apparatus and method for Immunohistochemistry, including a slide holder assembly fixture, a slide holder, a slide holder frame, and a slide holder frame assembly adapted to be placed in communication with a driving force to draw fluid through the slide holder. The slide holder may include an injection port that allows consistent fluid delivery and recovery, while minimizing the introduction of air bubbles. The slide holder may include a reservoir that allows for filling, soaking, rinsing, flushing, uniform antibody coverage of the tissue and reduces handling time, space, and errors, and one or more sample chambers. The slide orientation in the slide holder allows for visualization of label information and tissue to confirm adequate antibody coverage. A multi-port frame allows multiple assays to be carried out concurrently, and is removable from a vacuum manifold and allows for easy transport from the vacuum manifold to an incubator/refrigerator and back.Type: GrantFiled: February 10, 2015Date of Patent: April 28, 2020Assignee: EMD Millipore CorporationInventors: Chris Scott, Paul Sydlowski, John Doyle, Ryan Amara, Libby Kellard, Sara Gutierrez, Marc Emerick
-
Patent number: 10627362Abstract: A method and device for measuring blood glucose are provided. The device includes a strip receiving part having a plurality of pins therein, the pins being arranged in such a manner that at least one of the pins contacts at least one electrode formed in a blood glucose measurement strip when the blood glucose measurement strip is inserted into the strip receiving part; and a controller configured to identify a type of the blood glucose measurement strip inserted into the strip receiving part and to control application of a testing voltage configured in response to the identified type of the blood glucose measurement strip to each pin of the strip receiving part.Type: GrantFiled: July 31, 2015Date of Patent: April 21, 2020Assignee: Samsung Electronics Co., LtdInventors: Seong-Je Cho, Kwang-Bok Kim, Sun-Tae Jung, Jae-Geol Cho, Chul-Ho Cho
-
Patent number: 10625095Abstract: A pierce and fill connector cap for a vial sealed by an elastomeric septum includes a vial collar and a needle holder. The vial collar body defines a collar aperture to be positioned in overlying registry with the septum of the vial, and the needle holder includes a needle holder body providing a means for holding an elongate needle in registry with the collar aperture. The needle holder body being moveable with respect to said vial collar between a first position spaced from the vial collar and a second position proximate the vial collar, such that a needle held by the needle holder will puncture through the vial septum.Type: GrantFiled: July 17, 2017Date of Patent: April 21, 2020Assignee: GE HEALTHCARE LIMITEDInventors: Xavier Franci, Philippe Dumont, Svein-Erik Lindgaard
-
Patent number: 10625266Abstract: An embodiment of a reagent container includes a bottle with a pipe to reduce the effects of reagent sloshing. The bottle has an elongated base and an opposed cover connected by side walls and an end wall. A flat platform surrounded by a raised rim lies in the base opposite an opening in the cover. A ribbed pipe frictionally fits within the bottle opening and may attach to the anchor region leaving vent passages around the pipe. The pipe includes an aperture adjacent to the anchor region and oriented toward the end wall so that sloshed fluid has only a small effect on the level of reagent in the pipe during transfers. A modified blow molding process produces the anchor region by extending a pin a predetermined distance into a mold while the molded material is still plastic.Type: GrantFiled: March 13, 2017Date of Patent: April 21, 2020Assignees: Beckman Coulter, Inc., DTIL Ireland Holdings LimitedInventors: Hiroyuki Onishi, Masato Kayahara, Hiroshi Suzuki, Ryusuke Furuya, Naoki Mukaiyama, Michael Cooney, Marcus O'Neill, Sean O'Mahony
-
Patent number: 10621411Abstract: A method for laser microdissection includes detecting at least a portion of an object to be dissected in an image-producing manner in a laser microdissection system and generating a first digital object image. A first processing specification is defined based on the first digital object image. In a first processing step, the object is processed using a laser beam of the laser microdissection system in accordance with the first processing specification. At least a portion of the object is detected in an image-producing manner and a second digital object image is generated. A second processing specification is defined during execution of the first processing step based on the second digital object image. In a second processing step, the object is processed using the laser beam of the laser microdissection system in accordance with the second processing specification.Type: GrantFiled: January 19, 2015Date of Patent: April 14, 2020Assignee: LEICA MICROSYSTEMS CMS GMBHInventors: Falk Schlaudraff, Andrew Lee, Florian Hoffmann
-
Patent number: 10613027Abstract: Techniques for forming nanoribbon or bulk graphene-based SPR sensors are provided. In one aspect, a method of forming a graphene-based SPR sensor is provided which includes the steps of: depositing graphene onto a substrate, wherein the substrate comprises a dielectric layer on a conductive layer, and wherein the graphene is deposited onto the dielectric layer; and patterning the graphene into multiple, evenly spaced graphene strips, wherein each of the graphene strips has a width of from about 50 nanometers to about 5 micrometers, and ranges therebetween, and wherein the graphene strips are separated from one another by a distance of from about 5 nanometers to about 50 micrometers, and ranges therebetween. Alternatively, bulk graphene may be employed and the dielectric layer is used to form periodic regions of differing permittivity. A testing apparatus and method of analyzing a sample using the present SPR sensors are also provided.Type: GrantFiled: August 1, 2016Date of Patent: April 7, 2020Assignee: International Business Machines CorporationInventors: Phaedon Avouris, Damon B. Farmer, Yilei Li, Hugen Yan
-
Patent number: 10613109Abstract: The objective of this disclosure is to provide a dispensing apparatus that is capable of precisely dispense micro volume liquid samples without physically damaging the nozzle tip or the liquid containers. An example of the present disclosure images a droplet of a liquid sample, and dispenses the liquid sample using an image of the droplet.Type: GrantFiled: January 8, 2018Date of Patent: April 7, 2020Assignee: HITACHI, LTD.Inventor: Takahiro Ando
-
Patent number: 10605717Abstract: An apparatus for analyzing urine, including: a feeding and discharging device that delivers a quantity of urine into an analysis chamber of a urine test strip and discharges a quantity of urine from an analysis chamber of a urine test strip, the analysis chamber having an analysis zone. The feeding and discharging device includes a movably mounted feeding and/or discharging element for delivering a quantity of urine into a delivery zone in the analysis chamber and/or discharging a quantity of urine from a discharge zone in the analysis chamber. A detection device detects an at least sectoral variation of an optically detectable parameter, which varies in an optically detectable manner in accordance with the composition of a quantity of urine that contacts the analysis zone and produces detection data describing at least one optically detected parameter in the analysis zone or a variation of such a parameter.Type: GrantFiled: October 5, 2015Date of Patent: March 31, 2020Assignee: DURAVIT AKTIENGESELLSCHAFTInventors: Bernd Spangenberg, Dirk Jansen, Bernd Kaiser
-
Patent number: 10596574Abstract: The invention relates to an incubation tray having a depression formed by the walls of the incubation tray and having a base, wherein the incubation tray has a means for drawing off liquid on at least one longitudinal end of the depression, preferably an opening which opens into an outlet channel on the longitudinal end of the depression, particularly preferably in a wall of the incubation tray, wherein the opening and the outlet channel are designed such that negative pressure can be applied, wherein the incubation tray is pivotable about the transverse axis of the incubation tray, and wherein the incubation tray can be equipped with a support.Type: GrantFiled: December 21, 2015Date of Patent: March 24, 2020Assignee: Euroimmun Medizinische Labordiagnostika AGInventor: Christian Kaffka
-
Patent number: 10597694Abstract: A sample preparation device comprising a first chamber containing a first movable piston separating a first volume upstream and a second volume downstream the first piston, a second chamber containing a second movable piston separating a third volume upstream and a fourth volume downstream the second piston, and an inlet to the first volume and an outlet from the first volume. The first volume is connected with the third volume by a first communication path and the second volume is connected with the fourth volume by a second communication path.Type: GrantFiled: March 31, 2015Date of Patent: March 24, 2020Assignee: Merck Patent GmbHInventor: Stephane Olivier
-
Patent number: 10595762Abstract: A specimen transfer device adapted to receive a blood sample is disclosed. The specimen transfer device includes a housing and an actuation member. A deformable material is disposed within the housing and is deformable from an initial position in which the material is adapted to hold the sample to a deformed position in which at least a portion of the sample is released from the material. A viscoelastic member is disposed within the housing between the material and the housing and between the material and the actuation member. The viscoelastic member is engaged with the actuation member and the material such that movement of the actuation member from a first position to a second position deforms the material from the initial position to the deformed position.Type: GrantFiled: April 13, 2016Date of Patent: March 24, 2020Assignee: Becton, Dickinson and CompanyInventors: Milan Ivosevic, Bradley M. Wilkinson, C. Mark Newby, Kishore K. Bokka Srinivasa Rao
-
Patent number: 10589250Abstract: A device for purifying and formulating a radiopharmaceutical compound includes an automated purification subsystem that automates the loading of a sample into a sample loop for downstream purification via HPLC. A column selector valve is provided to select from one of a plurality of columns. Fractions can be collected as well as the desired product. The device includes an automated formulation subsystem that first sends the product to a dilution reservoir prior to being pneumatically pushed onto a solid phase extraction (SPE) cartridge. Automated rinse, elution, and reconstitution are also performed with the automated formulation subsystem. The device may be directly coupled to the output of an automated radiosynthesizer.Type: GrantFiled: September 7, 2017Date of Patent: March 17, 2020Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, SOFIE BIOSCIENCES, INC.Inventors: Eric Schopf, Melissa Moore, R. Michael van Dam, Brandon Maraglia, Alexander Hsiao
-
Patent number: 10589275Abstract: A device for separating and concentrating target particles or molecules from a fibrinogen containing sample of liquid comprises a container (1) for collecting the sample and a closure (2). The container (1) comprises a first end and a second end and at least one interior wall defining a reservoir portion (5) for receiving the sample. The reservoir portion (5) comprises at least one anchor element (4) to locally catch a polymerized fibrin pellet formed upon the addition of the sample into the container. The separation and concentration process is operated by trapping the target particles or molecules into the so-formed polymerized fibrin pellet that are captured on the anchor element (4).Type: GrantFiled: June 1, 2015Date of Patent: March 17, 2020Assignee: DEBIOPHARM INTERNATIONAL S.A.Inventors: Amar Rida, Sélène Ferrari
-
Patent number: 10584078Abstract: The invention provides a new chemical process, a new cassette configuration, and new software. The invention allows one synthesizer in one hot cell to produce sequentially two batches of [18F]-labelled PET tracer in the same day.Type: GrantFiled: November 12, 2014Date of Patent: March 10, 2020Assignee: GE HEALTHCARE LIMITEDInventor: Xavier Franci