Abstract: A system and method includes transmission of an ultrasound push pulse toward material along a first axis, the ultrasound push pulse associated with a first frequency, a first F number, and a first focal depth, determination of displacement of the material along the axis in response to the push pulse, transmission of a second ultrasound pulse toward the material along the first axis, the second ultrasound pulse associated with a second frequency, a second F number, and a second focal depth substantially similar to the first frequency, the first F number, and the first focal depth, respectively, reception of echo signals from the material in response to the second ultrasound pulse, beamforming of the echo signals based on the first F number and a fixed focus at the first focal depth, determination of a magnitude of the beamformed echo signals along the axis, determination of relative elasticity of the material along the axis based on the determined displacement of the material along the axis and the magnitude o

Abstract: Methods for locating blood vessels, lesions, and other discontinuities in tissue such as, but not limited to, the greater palatine artery (GPA) in the hard palate using an optical imaging process, surgical procedures utilizing the identified locations of discontinuities, and devices suitable for use during surgical procedures. According to one aspect, such a method locates a blood vessel or lesion in tissue by imaging the tissue via a diffuse optical imaging (DOI) process that measures light that travels through the tissue, and then locates the blood vessel or lesion in the tissue based on a difference in absorption of the light between the tissue and the blood vessel or lesion.

Abstract: Embodiments receive images of a body area of a patient; identify abnormal tissue in the image; generate a data set with the abnormal tissue masked out; deform a model template in space so that features in the deformed model template line up with corresponding features in the data set; place data representing the abnormal tissue back into the deformed model template; generate a model of electrical properties of tissues in the body area based on the deformed and modified model template; and determine an electrode placement layout that maximizes field strength in the abnormal tissue by using the model of electrical properties to simulate electromagnetic field distributions in the body area caused by simulated electrodes placed respective to the body area. The layout can then be used as a guide for placing electrodes respective to the body area of the patient to apply TTFields to the body area.

Abstract: Methods and systems for suppressing clutter effects in ultrasonic imaging systems are presented. Two or more receive beams with different and distinct beam patterns are employed for each reception boresight and each reception phase center. The clutter suppression processing is applied to the beamformed data, and is based on computing one or more features for each range-gate. These features may include variability features, providing an estimate of the variability of the signal received by the different elements of the transducer array for the range-gate, and/or derivative/slope features that are an estimation of a function of spatial derivatives of the signal received by the different elements of the transducer array for the range-gate.

Abstract: A method of controlling a photoacoustic imaging diagnosis apparatus includes irradiating to an object an optical signal having a wavelength corresponding to an optical energy absorption wavelength of a contrast medium that is injected to the object; receiving a photoacoustic signal generated from the object in response to the optical signal; generating scan information representing an intensity of the photoacoustic signal based on the photoacoustic signal; determining a damage degree of the object by using a variation in the intensity of the photoacoustic signal during a preset time period included in the scan information; and displaying the damage degree of the object.

Abstract: A spectral Doppler processor for an ultrasound system produces blood flow velocity estimates by processing a sequence of complex blood flow echo samples with an FFT algorithm. The FFT algorithm is executed with a long window of samples to produce velocity estimates with good velocity precision and is executed with a short window of samples to produce velocity estimates with good time precision. The long window algorithm is used when blood flow velocity is not changing rapidly, and the short window algorithm is used when blood flow velocity is changing rapidly.

Abstract: A computer-implemented method for decoding brain imaging data of individual subjects by using additional imaging data from other subjects includes receiving a plurality of functional Magnetic Resonance Imaging (fMRI) datasets corresponding to a plurality of subjects. Each fMRI dataset corresponds to a distinct subject and comprises brain activation patterns resulting from presentation of a plurality of stimuli to the distinct subject. A group dimensionality reduction (GDR) technique is applied to the example fMRI datasets to yield a low-dimensional space of response variables shared by the plurality of subjects. A model is trained to predict a set of target variables based on the low-dimensional space of response variables shared by all subjects, wherein the set of target variables comprise one or more characteristics of the plurality of stimuli.

Abstract: A clutter reduction effect using adaptive beam forming is uniformly obtained with respect to the entire image even in an imaging condition in which the number of bundled signals is greatly distributed in an ultrasonic image. A received signal processing unit includes a summing unit that bundles the plurality of received signals for a predetermined imaging point or a plurality of signals obtained by processing the received signals, and a weighting unit that obtains a coherence value among the plurality of signals summed in the summing unit, and weights the plurality of signals before being summed in the summing unit or a signal obtained through summing in the summing unit, with a weight corresponding to the coherence value. The weighting unit weights the coherence value nonlinearly in a predetermined direction in the subject, and weights the plurality of signals before being summed in the summing unit or the signal obtained through summing in the summing unit by using the nonlinearly weighted coherence value.

Abstract: A post-processing leakage correction system and method that accounts for bidirectional contrast agent transport between the intravascular and interstitial spaces that commonly occurs in angiogenic high-grade gliomas without a substantial increase in post-processing computation time.

Abstract: An apparatus includes a processing assembly, a plurality of field generators, and a patient tracking assembly. The patient tracking assembly includes a sensor assembly and a communication assembly. The sensor assembly includes a first body, a first sensor, and an electrical conduit. The first body selectively attaches to a patient. The first sensor is mounted to the first body and generates a signal in response to movement within an electromagnetic field. The communication assembly includes a second body and a cable. The second body rotates relative to the first body from a first rotational position to a second rotational position. The cable extends away from the second body. The cable communicates with the processing assembly. The electrical conduit couples the first sensor with the cable while the casing is in the first rotational position and the second rotational position.

Abstract: A simulated method and system for surgical instrument based on tomography are provided. The method includes obtaining a biological stereoscopic image and inputting a parameter set of an implant to be implanted, denoting a target position and an initial position in the biological stereoscopic image, estimating a dimensional coordinate of a contact area of the implant and a living organism when the implant has been implanted into the living organism based on the parameter set, the target position and the initial position in the biological stereoscopic image, and obtaining a physiological data set by re-sampling corresponding to the dimensional coordinate of the implant in the living organism for evaluating the effect after the implant has been implanted into the living organism. Surgeons may evaluate the effect after implantation of implant into the living organism by using the simulated method, enhancing the overall quality and result of the surgery.

Abstract: An ultrasound transducer module includes: an ultrasound transducer configured to transmit and receive ultrasound; a substrate electrically connected with the ultrasound transducer and including a first wiring pad at a portion different from a connection portion with the ultrasound transducer; and a casing that includes an accommodation hole for accommodating the ultrasound transducer and the substrate and that includes a holding hole continued to the accommodation hole and capable of holding a portion of the substrate, the casing having a plurality of electrode pads provided on an outer surface of the casing and having a plurality of second wiring pads provided in the holding hole, each second wiring pad being electrically connected with a corresponding electrode pad among the plurality of electrode pads, and electrically connected with the first wiring pad.

Abstract: A surgical instrument includes a catheter, a distal segment, a needle, and a tracking sensor. The catheter is configured to be inserted into an anatomical passageway of a patient and includes a catheter lumen. The distal segment includes a port that communicates with the catheter lumen. The needle is slidably disposed within the catheter lumen and is translatable relative to the catheter between a retracted position and an extended position. A needle distal end is configured to extend through the port when the needle is in the extended position. The tracking sensor is coupled to the needle and is configured to generate a signal corresponding to a location of the needle distal end within the patient.

Abstract: For sound speed imaging, different receive apertures are used instead of multiple transmissions from different angles. Acoustic echoes from a same transmission are receive beamformed with different apertures of the transducer array. The axial shift between the beamformed signals from the different apertures is used to solve for the speed of sound at one or more locations. The resulting measure of the speed of sound is displayed as the speed of sound in the tissue and may be diagnostically or prognostically useful.