Abstract: A surgical access assembly and method of use is disclosed. The surgical access assembly comprises an outer sheath and an obturator. The outer sheath and obturator are configured to be delivered to an area of interest within the brain. Either the outer sheath or the obturator may be configured to operate with a navigational system to track the location of either device within the brain.

Abstract: A catheter system is disclosed, having a plurality of expandable arms with radiopaque markers at their ends. Once deployed at a patient's valve, a user can obtain a correct 3D localization image for placement of the replacement valve by aligning the radiopaque markers to be substantially equidistant from each other and substantially located in the same plane, relative to the sensor of an X-Ray machine.

Abstract: Methods, devices, and systems are disclosed for implementing a fully quantitative non-injectable contrast proton MRI technique to measure spatial ventilation-perfusion (VA/Q) matching and spatial distribution of ventilation and perfusion. In one aspect, a method using MRI to characterize ventilation and perfusion in a lung includes acquiring an MR image of the lung having MR data in a voxel and obtaining a breathing frequency parameter, determining a water density value, a specific ventilation value, and a perfusion value in at least one voxel of the MR image based on the MR data and using the water density value to determine an air content value, and determining a ventilation-perfusion ratio value that is the product of the specific ventilation value, the air content value, the inverse of the perfusion value, and the breathing frequency.

Abstract: A wearable device includes a detector configured to detect a response signal transmitted from a portion of subsurface vasculature, the response signal being related to binding of a clinically-relevant analyte to functionalized particles present in a lumen of the subsurface vasculature. Program instructions stored in a computer readable medium of the device, and executable by a processor, may cause the device to determine a concentration of the clinically-relevant analyte based on the response signal detected by the detector; determine whether a medical condition is indicated based on at least the concentration of the clinically-relevant analyte; and, in response to a determination that the medical condition is indicated, transmit data representative of the medical condition via the communication interface.

Abstract: A surgical imaging system can include at least one light source, configured to generate a light beam; a beam guidance system, configured to guide the light beam from the light source; a beam scanner, configured to receive the light from the beam guidance system, and to generate a scanned light beam; a beam coupler, configured to redirect the scanned light beam; and a wide field of view (WFOV) lens, configured to guide the redirected scanned light beam into a target region of a procedure eye; wherein the beam coupler is movably positioned relative to the procedure eye such that the beam coupler is selectively movable to change at least one of an incidence angle of the redirected scanned light beam into the procedure eye and the target region of the procedure eye.

Abstract: An intravascular imaging system can include a catheter, a position sensor, and an intravascular imaging engine for receiving information from the catheter and the position sensor. The position sensor can include a reference element and a movable element, which can have a movable element position that is correlated to the position of an imaging transducer in the catheter. The relative position between the movable element and a reference element can be determined and can correspond to the relative movement of the transducer within a patient's vasculature. The imaging engine can receive position information from the position sensor and image information from the catheter and generate a display using the received information. Because relative movement of the transducer can be determined, spatial relationships between sets of imaging data can be determined, and image data from multiple transducer locations can be combined into one image.

Abstract: Provided are an ultrasound system and a method of detecting a pressure applied to an object through an ultrasound probe. The ultrasound system includes: an ultrasound data acquiring unit configured to acquire, by using an ultrasound probe including a strain gauge that is strained by a pressure applied thereto and has a damping factor and an elasticity factor, ultrasound data corresponding to an object; and a processor configured to generate an ultrasound image by using the ultrasound data, calculate a strain rate of the strain gauge caused by the pressure by using the ultrasound image, and detect the pressure by using the strain rate calculated.

Abstract: A dedicated device for detection of vascular shunts can include a first chamber, a second chamber, and a third chamber. The first chamber can be configured to hold liquid, the second chamber to hold gas, and the third chamber can be in communication with the first and second chambers. The third chamber can include small-scale geometric features configured to produce gas bubbles as liquid from the first chamber and gas from the second chamber simultaneously flow into the third chamber. The device can also include a device opening in communication with the third chamber such that a mixture of liquid and gas bubbles can flow out of the device opening. The device can also include a plunger configured to force the liquid and the gas simultaneously from the first and second chambers, through the third chamber to mix with each other and produce bubbles, and further through the device opening.

Abstract: A method for computer assisted determination of values of correction parameters for positioning a medical device relative to a target structure or to a reference base. The method includes a numerical procedure that includes the steps of: i) automatic detection of the projection of a cylindrical reference means in a medical image and determination of a minimum of four characteristic landmarks within the projection of the cylindrical reference means; ii) generating a virtual geometric representation of the cylindrical reference means; iii) determining the virtual projection points representing the characteristic landmarks using a virtual geometric representation of the cylindrical reference means; and iv) iterative determination of the position and orientation of the cylindrical reference means by matching the virtual projection points of the virtual geometric representation of the cylindrical reference means with the characteristic landmarks of the projection of the cylindrical reference means.

Abstract: The embodiments herein discloses a device with simultaneous X-ray and infrared acquisition and processing systems for an enhance breast imaging. The device has a positioning assembly housed inside a closed chamber and provided with the Infrared and X-ray imaging systems to simultaneously capture an infra red image and an X-ray image of the breast under examination. A patient support table with an opening is provided to enable a patient to lie in a prone position without compressing a breast during imaging. The device is used to correlate anatomical and physiological characteristics and post process analysis of a breast tissue thereby reducing a number of to false positive results. Further the device helps in focusing on a suspected area in a follow-up procedure and aids post processing treatment like targeted biopsy and targeted radiation.

Abstract: In one aspect, an enhanced ultrasound device may generally comprise an ultrasound probe including a housing and at least one transducer element disposed within the housing. The ultrasound probe may be configured to generate ultrasound image signals associated with an object being imaged. In addition, the device may include an acoustic receiver associated with the ultrasound probe. The acoustic receiver may be configured to generate auscultation signals associated with sounds generated by the object as the object is being imaged using the ultrasound probe.

Abstract: The invention relates to a measuring device and to a method for measuring parameters of a body tissue using an elongate probe (1) for insertion into the body tissue, comprising at least one optical waveguide (2) for transmitting light beams that runs along the longitudinal axis of the probe within the probe, an exit region (5) from which light beams emitted from the optical waveguide exit into the body tissue, and at least one receiving region (6) through which light beams reflected and/or scattered in the body tissue enter the probe as input light beams on a photodetector or in an optical waveguide (2; 3). The exit region (5) is provided at the distal end of the probe (1) and is oriented at least partially in the longitudinal direction of the probe (1). At least some of the emitted light beams exit the probe in the longitudinal direction of the probe. The at least one receiving region (6) is located at a distance from the distal end of the probe on a lateral circumferential region of the probe.

Abstract: A method for real-time, high-density physiological data collection includes automatically measuring, by a wearable device, one or more physiological parameters during each of a plurality of measurement periods, and upon conclusion of a measurement period, for each of the plurality of measurement periods, automatically transmitting by the wearable device data representative of the physiological parameters measured during that measurement period, to a server, the server configured to develop a baseline profile based on the data transmitted by the wearable device for the plurality of measurement periods. The measurement periods may extend through a plurality of consecutive days, and each of the consecutive days may include multiple measurement periods. At least some of the physiological parameters are measured by non-invasively detecting one or more analytes in blood circulating in subsurface vasculature proximate to the wearable device.

Abstract: An ultrasound imaging system (300) includes a transducer array (302) with a two-dimensional array of transducer elements configured to transmit an ultrasound signal and receive echoes, transmit circuitry (304) configured to control the transducer array to transmit the ultrasound signal so as to traverse a field of view, and receive circuitry (306) configured to receive a two dimensional set of echoes produced in response to the ultrasound signal traversing structure in the field of view, wherein the structure includes flowing structure. A beamformer (312) configured to beamform the echoes, and a velocity processor (314) configured to separately determine a depth velocity component, a transverse velocity component and an elevation velocity component, wherein the velocity components are determined based on the same transmitted ultrasound signal and the same received set of two dimensional echoes.

Abstract: A system for modulating a response signal includes functionalized particles configured to interact with target analytes, a detector configured to detect an analyte response signal transmitted from the body, a modulation source configured to modulate the analyte response signal, and a processor configured to non-invasively detect the one or more target analytes by differentiating the analyte response signal from a background signal, at least in part, based on the modulation. The analyte response signal is related to the interaction of the target analytes with the functionalized particles. In some examples, the system may also include magnetic particles and a magnetic field source sufficient to distribute the magnetic particles into a spatial arrangement in the body. The analyte response signal may be differentiated from the background signal, at least in part, based on modulation of the signals due, at least in part, to the spatial arrangement of the magnetic particles.

Abstract: After light has been output to a subject to be examined, a photoacoustic wave induced in the subject by the output light is detected. It is assumed that at least one virtual detector element is present outside of a real detector, and dummy data corresponding to the at least one virtual detector element are added to photoacoustic data in which pieces of data of the photoacoustic wave detected by the detector are arranged in accordance with the positions of detector elements. A photoacoustic image is generated by reconstructing the photoacoustic data to which the dummy data have been added by using a Fourier transform method.

Abstract: An ultrasonic diagnosis device wherein a movable mechanism for supporting an operation panel is configured so that the degree of freedom in the position and attitude thereof is increased. Specifically, a movable section comprises the operation panel, a base, an arm mechanism, and a display unit. The movable mechanism has a lifting mechanism and a horizontal movement mechanism. The horizontal movement mechanism has a layered structure. The layered structure has, stacked from bottom to top, a left-right slide mechanism, a forward-backward slide mechanism, a rotation mechanism, and a rotation limitation mechanism. The rotation limitation mechanism changes a rotation range according to a sliding position in the forward-backward direction.

Abstract: Systems, methods, and computer-readable media are disclosed for identifying when a subject is likely to be affected by a medical condition. For example, at least one processor may be configured to receive information reflective of an external soft tissue image of the subject. The processor may also be configured to perform an evaluation of the external soft tissue image information and to generate evaluation result information based, at least in part, on the evaluation. The processor may also be configured to predict a likelihood that the subject is affected by the medical condition based, at least in part, on the evaluation result information.

Abstract: Spatial light response around a fingertip or toe of a subject in response to electrical stimulation can be associated to a specified remote particular body anatomy, location, component, or system such as for providing a particularized physiological status indicator or other particularized response indication that is particular to the specified particular body anatomy, location, component, or system.

Abstract: An arrangement is adapted to determine an estimate for mineral density related to a patient's first bone, wherein said first bone is associated with a femoral head, neck and/or a lumbar spine. The estimate determined by determining a first parameter, which is related to a property change in a measurement signal, most preferably an ultrasonic signal, launched towards some second bone of said patient other than the first bone after the measurement signal has been in interaction with said second bone. This is followed by determining an estimate for mineral density related to said patient's first bone by using said first parameter.