Patents Examined by Johann R. Richter
  • Patent number: 11219691
    Abstract: A microbial infection in an eye of a subject is treated or prevented by topically administering to the eye an effective amount of a macromolecule or a pharmaceutically acceptable salt thereof that includes a dendrimer of 1 to 8 generations with one or more sulfonic acid- or sulfonate-containing moieties attached to one or more surface groups of the outermost generation of the dendrimer. Compositions containing the macromolecule or salt are useful in these methods.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: January 11, 2022
    Assignee: Starpharma Pty Limited
    Inventors: Jacinth Kincaid Fairley, Colin Paul Barrett, Jeremy Robert Arthur Paull
  • Patent number: 11207429
    Abstract: Disclosed is CT or MR contrast agent which comprises a base or carrier scaffold formed of a polyhydroxol compound having a linker to which a Gd-DOTA is covalently bonded. Also disclosed is a method of screening a patient for colon cancer using a CT or MR contrast, which method comprises administering to a patient undergoing screening a compound as above described.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: December 28, 2021
    Assignee: Arizona Board of Regents on behalf of the University of Arizona
    Inventors: Eugene A. Mash, Parastou Foroutan, Suryakiran Navath, Robert J. Gillies, Gary V. Martinez, David L. Morse
  • Patent number: 11191800
    Abstract: The invention is directed to an aqueous extract of Eruca sativa (arugula) leaves that has antimicrobial activity on Gram-positive bacteria and mycoplasmas. The extract may be purified away from solid or insoluble components, standardized based on the weight of its non-aqueous or solid content, assayed for antimicrobial activity, and provided in an aseptic or sterile form for pharmaceutical use. It may be used to kill or inhibit the growth of microorganisms such as Gram positive bacteria, promote wound healing, or as prophylaxis against host colonization or infection by a microorganism.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: December 7, 2021
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Ines Mohsen Hammami, Azzah Ibrahim Alghamdi
  • Patent number: 11185561
    Abstract: The present invention provides an egg allergy prevention method to be carried out with respect to a human infant, including: a first administration period (first administration step) in which to administer, to an infant, heated egg white protein in an amount of 10 mg to 20 mg per day; and a second administration period (second administration step) which is a period after the first administration period and in which to administer, to the infant, the heated egg white protein in an amount of 65 mg to 90 mg per day.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: November 30, 2021
    Assignee: NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT
    Inventors: Yukihiro Ohya, Shigenori Kabashima, Osamu Natsume, Hirohisa Saito
  • Patent number: 11173131
    Abstract: The present invention relates to a transdermal device including porous microparticles capable of containing an active principle, in particular nicotine, and to the use thereof as a drug, in particular for tobacco cessation. The present invention further relates to a method for preparing a transdermal device including porous microparticles filled with an active principle.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: November 16, 2021
    Assignee: PIERRE FABRE MEDICAMENT
    Inventors: Isabel Ribeiro Dos Santos, Michel Sournac
  • Patent number: 11166940
    Abstract: Methods of inducing bradycardia (slowing a heart rate) in a subject in need thereof, treating a medical condition in which inducing bradycardia (slowing a heart rate) is desirable or beneficial in a subject in need thereof and/or treating a medical condition associated with cardiac arrhythmia, are provided. The methods are effected by blocking SK4 channel in SAN cell of the subject and/or by administering to the subject a therapeutically effective amount of a blocker of an SK4 channel. A method of identifying candidate compounds for treating an arrhythmic cardiac disorder, by identifying compounds that reduce a pacing rate of the SAN cells is also provided.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: November 9, 2021
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: David Weisbrod, Bernard Attali, Asher Peretz
  • Patent number: 11166456
    Abstract: A deposition aid is provided, comprising a low molecular weight, low viscosity polysiloxane, combined with a crop oil concentrate or esterified seed oil concentrate. Combinations including the modified silicone can improve spreading and/or adhesion to foliage. Adding about 5% to about 20% of the modified silicone can provide more than a proportional increase in spreading and/or adhesion.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: November 9, 2021
    Assignee: Momentive Performance Materials Inc.
    Inventors: William L. Brown, George A. Policello, Jeferson A. Naue
  • Patent number: 11122798
    Abstract: Aqueous pesticidal mixtures comprising a microencapsulated pesticide and an agent that modulates the release rate of the pesticide from the microcapsules are described. Also described are various methods of modulating the release rate of a microencapsulated pesticide in a pesticidal mixture. Further, various pesticidal mixtures comprising a microencapsulated pesticide and a co-pesticide that provides for enhanced crop safety are described.
    Type: Grant
    Filed: March 16, 2020
    Date of Patent: September 21, 2021
    Assignee: Monsanto Technology LLC
    Inventors: Wenjin Deng, Todd Charles Friedman, John W. Hemminghaus, Liwei Yuan, Junhua Zhang
  • Patent number: 11098055
    Abstract: The present invention provides ester compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: August 24, 2021
    Assignee: Gilead Apollo, LLC
    Inventors: Shomir Ghosh, Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit De Moradei
  • Patent number: 11089785
    Abstract: Anti-microbial metabolites secreted from various bacterial and/or fungal species are described that have anti-bacterial activity against Xanthomonas species, which cause disease in plant hosts, including a wide variety of crops. Bacterial and fungal species producing such metabolites were identified from environmental samples (seeds, different vegetable organs and soil) from different geographic locations. Compositions, methods, uses, and kits 5 relating to the identified anti-microbial metabolites are also described.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: August 17, 2021
    Assignee: Institut National De U Recherche Scientifique
    Inventors: Fadi Dagher, Eric Deziel, Snizhana Olishevska
  • Patent number: 11083200
    Abstract: A plant protection agent includes a photocatalyst particle containing a titanium oxide compound. The surface of the photocatalyst particle is modified with a metal compound that includes a metal atom and a hydrocarbon group. The photocatalyst particle has absorption at a wavelength of 550 nm.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: August 10, 2021
    Assignee: FUJIFILM Business Innovation Corp.
    Inventors: Hiroyoshi Okuno, Hideaki Yoshikawa, Takeshi Iwanaga, Sakae Takeuchi, Yuka Zenitani, Yasuhiro Kusumoto
  • Patent number: 11077030
    Abstract: The present application relates to sunscreen formulations, including foamable sunscreen formulations, that comprise zinc oxide and titanium dioxide particles, suitably in the size range of about 1-100 nm. The compositions suitably produce a minimal residual whitening effect when applied to a skin surface.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: August 3, 2021
    Assignee: FALLIEN COSMECEUTICALS, LTD.
    Inventors: David J. Milora, Harry Fallick
  • Patent number: 11076594
    Abstract: The present invention belongs to the field of pesticides, particularly relates to a pyrazolone compound or a salt thereof, a preparation method therefor, a herbicidal composition and use thereof. The pyrazolone compound is as described in formula I: In the formula, R1R2N represents substituted or unsubstituted 3-8 membered nitrogen-containing heterocyclic group containing 1-3 heteroatoms; or R1 and R2 each represent hydrogen or C1-8 alkyl; R3 represents hydrogen, C1-4 alkyl, alkenyl, alkynyl, unsubstituted C3-6 cycloalkyl or C3-6 cycloalkyl substituted by C1-4 alkyl; R4 represents methyl, ethyl, n-propyl, isopropyl or cyclopropyl; X represents hydrogen, —S(O)nR6, —R7 or substituted or unsubstituted 3-8 membered heterocyclic group containing 1-4 heteroatoms, wherein, n represents 1, 2 or 3, R6 represents substituted or unsubstituted alkyl or aryl, and R7 represents substituted or unsubstituted alkyl, aryl, alkyl acyl or aroyl.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: August 3, 2021
    Inventors: Lei Lian, Yurong Zheng, Bin He, Xuegang Peng, Tao Jin, Qi Cui
  • Patent number: 11078127
    Abstract: Embodiments of the invention relate to a method of making a mineral product. The method includes contacting a carboxylic acid and an inorganic mineral compound sufficient to form a solution, reacting the solution over a period of time sufficient to provide a mineral chelated compound, transferring the mineral chelated compound to one or more molds prior to the compound substantially solidifying and reducing the size of the mineral chelated compound sufficient to provide a rapidly soluble mineral chelated product.
    Type: Grant
    Filed: March 20, 2020
    Date of Patent: August 3, 2021
    Assignee: RALCO NUTRITION, INC.
    Inventors: Brian Jon Knochenmus, Jon Kent Knochenmus, Richard Dale Lamb, Myrra Arlene Lamb
  • Patent number: 11071299
    Abstract: Miticide composition of prolonged action against Varroa destructor of bees comprising oxalic acid, glycerin, 4-carbon dicarboxylic acid and formic acid and its manufacturing process. A cellulose trip impregnated in said miticide composition, which is introduced in the bee hives and its manufacturing processes.
    Type: Grant
    Filed: April 22, 2014
    Date of Patent: July 27, 2021
    Assignee: Coop, de Trabajo Apicola Pampero Ltda.
    Inventors: Elian Tourn, Danilo Rubenacker, Diego Iaconis, Gabriel Gomez, Luciano Marcelo Morales Pontet, Alfredo Marconi, Evangelina Mirta Torres
  • Patent number: 11066341
    Abstract: Disclosed herein are microbial consortia and compositions including microbes for example for use in agricultural or biodegradation applications. In some embodiments, soil, plants, and/or plant parts (such as seeds, seedlings, shoots, roots, leaves, fruit, stems, or branches) are contacted with a disclosed microbial consortia or composition including microbes. The microbial consortia or microbe-containing compositions may be applied to soil, plant, and/or plant parts alone or in combination with additional components (such as chitin, chitosan, glucosamine, amino acids, and/or liquid fertilizer). In additional embodiments, the disclosed microbial consortia or compositions including microbes are used in methods of degrading biological materials, such as chitin-containing biological materials.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: July 20, 2021
    Assignee: AMVAC Chemical Corporation
    Inventors: Sung-Yong H. Yoon, Kathleen Swords, D. Ry Wagner, Xing Liang Liu
  • Patent number: 11058771
    Abstract: A patch for treating vascular ulcers caused by excessive enzymatic activity may include a substrate configured to span a vascular ulcer as well as a linking material that is disposed relative to the substrate and has an affinity for an enzyme involved in causing the vascular ulcer. A magnetic material may be coupled to the linking material. In some cases, the enzymes involved in causing the vascular ulcer may become coupled to the linking material and thus become coupled to the magnetic material so that that the enzymes can be removed by applying a magnetic field in the proximity of the vascular ulcer. The enzymes may include matrix metalloproteinases.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: July 13, 2021
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventor: Matthew Hunt
  • Patent number: 11058116
    Abstract: The invention relates to agriculture, to stimulation of germination in agricultural plants and seeds in the initial growth phase. The composition activates plant growth and induces resistance to biotic and abiotic stresses, to reduce incidence of micromycetes damaging the root system. The composition includes a liquid solution containing a water-soluble silicon-organic compounds containing potassium silicate or sodium silicate; the liquid solution including a solvent to dissolve the water-soluble silicon-organic compounds; salicylate in an amount of 0.1% to 2% by volume; the liquid solution also containing succinate and citrate as an acidity regulator; at least one chelate; and at least one trace element and/or at least one carboxylic acid and/or at least one amino acid. The pH of the composition is from 6.5 to 10.9.
    Type: Grant
    Filed: February 5, 2019
    Date of Patent: July 13, 2021
    Assignee: AGRATEK PTE. LTD.
    Inventors: Aleksei Valentinovich Kramarenko, Sergey Konstantinovich Sayfudinov, Dmitry Mikhaylovich Mikhaylov
  • Patent number: 11052153
    Abstract: Compositions including a highly branched alpha-D-glucan or modified forms thereof and a solute compound are described herein. The compositions can provide increased water solubility and/or increased rate of dissolution for the solute compound. The compositions can also provide increased stability for the solute compound. Methods for preparing and using compositions including a solute compound and a highly branched alpha-D-glucan are also described.
    Type: Grant
    Filed: October 8, 2018
    Date of Patent: July 6, 2021
    Assignee: Purdue Research Foundation
    Inventors: Yuan Yao, Jingmin Joanne Zhang
  • Patent number: 11045398
    Abstract: A cosmetic composition for brightening skin and a method for brightening skin using the cosmetic composition are provided. The cosmetic composition has a pH<7, and includes an oxidizing agent, in some embodiments comprising hydrogen peroxide, and at least one fatty compound present from about at least 30% by weight, based upon the total weight of the composition. The method for brightening skin includes applying to the skin a composition provided as a single-part system, the system including the oxidizing agent and a fatty compound component.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: June 29, 2021
    Assignee: L'OREAL
    Inventors: Rebecca Chen, Anne-Laure Suzanne Bernard, Mickael Ange Agach, Leila Safia Camille Hercouet, Etienne Huguet