Abstract: Disclosed is a pharmaceutical composition for oral administration, comprising 1-{5-[(5-{[(2R)-2-ethylpyrrolidin-1-yl]methyl}-4-[4-methoxy-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl)carbamoyl]pyrazin-2-yl}pyperidine-4-carboxylic acid, which is a compound having pH-dependent solubility, or a pharmaceutically acceptable salt thereof, and a cellulose derivative. In the pharmaceutical composition for oral administration, the solubility and absorbability of the drug are improved.

Abstract: The present application relates to sunscreen formulations, including foamable sunscreen formulations, that comprise zinc oxide and titanium dioxide particles, suitably in the size range of about 1-100 nm. The compositions suitably produce a minimal residual whitening effect when applied to a skin surface.

Abstract: Disclosed herein are plant propagation materials, methods of manufacturing, formulations and uses thereof. The plant propagation materials disclosed herein may comprise a strigolactone obtained by a biosynthetic process. The plant propagation material may comprise a chemical mimic of a strigolactone. The strigolactone may be 5-deoxystrigol. Methods of manufacturing the plant propagation materials may comprise a chemical process. Alternatively, methods of manufacturing the plant propagation material may comprise a biosynthetic process. The methods may comprise use of one or more polynucleotides. The polynucleotides may encode a metabolite. The polynucleotides may comprise one or more genes encoding one or more components of a strigolactone pathway.

Abstract: The present invention relates to compositions and methods for treating and/or preventing chronic- or UV-induced photodamage in the skin as well as damage to the skin caused by chronological aging and disease. Specifically, select aryl alkanones have been found to induce/produce a number of beneficial effects in the skin and skin processes by elevating the skin's defense against UV-induced damage and reversing skin photo- and/or chronological damage in the extracellular matrix (ECM) and dermal-epidermal junction (DEJ), up-regulating tissue inhibitory metalloproteases, reducing oxidative stress, inhibiting activity of matrix metalloproteases, and protecting DNA.

Abstract: Provided is a radioactive labeled compound capable of detecting a secondary mutation of an epidermal growth factor receptor, where the compound is represented by Formula (1) or a pharmaceutically acceptable salt thereof, where R1, R2, and Y are as defined.

Abstract: A microsphere and method for forming the same are disclosed. The microsphere includes modified cellulose and at least one of a visualization agent, a magnetic material, or a radioactive material.

Abstract: The present disclosure comprises compositions and methods for bioprotection, such as enhancing antimicrobial activity and decreasing abiotic stress. For example, the present disclosure comprises compositions and methods for affecting, enhancing, modulating, or decreasing antimicrobial activity.

Abstract: Pharmaceutical compositions are described, the compositions comprising a therapeutically effective quantity of an active component and a quantity of a sterile gel. Methods for fabricating the compositions and using them for ophthalmic or burn-treating applications are also described.

Abstract: The present invention relates to the technical field of pesticides, particularly relates to a pyrazole compound or a salt thereof, a preparation method therefor, a herbicidal composition and use thereof. A pyrazole compound of formula (I) or a salt thereof: wherein, R1 represents hydrogen or C1-C4 alkyl; R2 represents C1-C3 alkyl; R3 represents C1-C6 linear chain or cyclic group containing one or more heteroatoms selected from O, S, and N; R4 represents C1-C3 alkyl or halogen; R5 represents pyrazole ring or pyrazole ring substituted with one or more groups selected from alkyl, alkoxyl, halogen, halogenated alkyl, amino, and nitro. The pyrazole compound is an excellent herbicide with broad spectrum biological activity and outstanding safety for crops.

Abstract: The present invention generally relates to bacteriologically pure bacterial cultures of novel strains of plant growth-promoting bacteria, and inoculums comprising the same. The invention is also directed to plant seeds coated with the inoculums, kits comprising the inoculums and methods for stimulating plant growth by applying the biologically pure bacterial culture or the inoculum to a plant, plant seed, or plant growth medium.

Abstract: Disclosed is a pharmaceutical composition for oral administration, comprising 1-{5-[(5-{[(2R)-2-ethylpyrrolidin-1-yl]methyl}-4-[4-methoxy-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl)carbamoyl]pyrazin-2-yl}pyperidine-4-carboxylic acid, which is a compound having pH-dependent solubility, or a pharmaceutically acceptable salt thereof, and a cellulose derivative. In the pharmaceutical composition for oral administration, the solubility and absorbability of the drug are improved.

Abstract: An adjuvant composition contains lecithin and an organosilicon surfactant as defined herein.

Abstract: A conjugate represented by general formula (I), wherein R0 is a C1-6 alkyl, B is an anesthetic, and A is a linking group, and a quaternary ammonium salt is formed at the linking position between B and R0. The conjugate has a prolonged analgesic effect, and can be used in postoperative analgesia or treatment for chronic pain.

Abstract: The present invention relates to a microcapsule suspension containing (1) an oil core compound having a pesticide active agent dispersed in an oil compound, (2) an aqueous solution containing a polycationic colloid and a polyanionic colloid in a ratio that the polycationic colloid is from 0.02 to 1% by weight and the polyanionic colloid is from 0.02 to 2% by weight, and (3) a pH adjuster.

Abstract: The present invention is related to compositions comprising 3-phenyluracils I, wherein the variables R1 to R7 are as defined in the specification, including their agriculturally acceptable salts; and N-[[4-[(cyclopropylamino)carbonyl]phenyl]sulfonyl]-2-methoxy-benzamide II including its agriculturally acceptable salts; and optionally at least one herbicide III selected from the classes III.1) to III.15) defined as in the specification including their agriculturally acceptable salts and, provided they have a carboxyl group, their agriculturally acceptable derivatives.

Abstract: A paddy seed treatment agent containing a herbicidal active component and having a sufficient herbicidal effect, while having a reduced risk of herbicide injury to paddy rice, a method for treating paddy seeds using the paddy seed treatment agent, paddy seeds, and a method for controlling paddy field weeds by sowing and cultivating the paddy seeds, are provided. The paddy seed treatment agent contains fenquinotrione or a salt thereof as a herbicidal active component. The method for controlling paddy field weeds includes sowing and cultivating paddy seeds treated with this paddy seed treatment agent, and the like.

Abstract: Disclosed is to a composition including difethialone, containing a configurational stereoisomer of difethialone, referred to as a hetero-stereoisomer, of formula 3-(4?-bromobiphenyl-4-yl)-1-(4-hydroxythiocoumarin-3-yl)-1,2,3,4-tetrahydronaphthalene, in which the carbon atoms 1 and 3 of the 1,2,3,4-tetrahydronaphthalene group have different absolute configurations, the composition including an amount of a dextrorotatory enantiomer of the hetero-stereoisomer such that the ratio of this amount to the amount of difethialone in the composition is less than 10%; the amount of the dextrorotatory enantiomer of the hetero-stereoisomer of difethialone in the composition being different from the amount of levorotatory enantiomer of the hetero-stereoisomer of difethialone in the composition.

Abstract: The present invention belongs to the technical field of synergistic pesticides, and particularly relates to a synergistic herbicidal composition comprising a 4-benzoylpyrazole compound. The synergistic herbicidal composition comprises an active ingredient A and an active ingredient B in an herbicidally effective amount, wherein, the active ingredient A is the compound of the active ingredient B is one or more compounds selected from: 1) a phenoxycarboxylic acid; 2) a pyridinecarboxylic acid; 3) a benzoic acid; 4) a hydroxybenzonitrile; 5) an urea; 6) a pyridine; 7) a triazolinone; 8) a diphenyl ether; 9) an acetamide; 10) an aryloxyphenoxypropionate; 11) a cyclohexanedione; 12) a sulfonylurea; 13) a triazine; 14) a sulfonamide; 15) a phenylpyrazoline; and 16) others: bentazon. The composition is effective for controlling a broad-leaved weed in wheat fields, has extended weed-controlling spectrum, significant synergistic effect and reduced application rate, and is safe for a crop.

Abstract: The invention encompasses a nontoxic agricultural formulation of a concentrated liquid suspension comprising an organic phase and suspended particulate materials, and also encompasses an aqueous formulation comprising the concentrated liquid suspension and an agricultural treatment agent. The invention additionally encompasses methods of treating an agricultural target, comprising providing an agricultural formulation of a concentrated liquid suspension comprising an organic phase and suspended particulates, and applying the agricultural formulation onto the agricultural target, thereby treating the agricultural target.

Abstract: The invention relates to inhibitory compounds of a p38 MAP kinase having a structure of type (I)-(VII) which can be used for the treatment or prophylaxis of adhesion. Pharmaceutical compositions are disclosed containing an effective amount of the substance SB203580 or one or more of the conjugated compounds of type (I)-(VII) or a combination thereof, and a pharmaceutically acceptable carrier, a diluent or an excipient. Also disclosed is the use of the substance SB203580 as an agent having anti-adhesion activity. Also disclosed is a method for the prophylaxis and/or treatment of a disease or a condition in which there is a possibility of the formation and/or growth of adhesions, which makes it possible to dispense with the additional administration of a preparation in the post-operative period.