Abstract: A system for learning actual phacoemulsification energy setpoints at the time of occlusion breaks during ophthalmic surgery. Phacoemulsification energy setpoints may be recorded over different periods of time, such as during current cases and over a lifetime of cases. The recorded data would then be used to determine future phacoemulsification energy setting amounts.

Abstract: Disclosed herein are catheter control handles that include various mechanisms for controlling the circumferential angle and radial magnitude of flexion of an attached catheter. Control handles can comprise a housing. Control wires extend from a distal end of the housing and into a steerable transluminal device. A flex control member is operable to control tension on the pull wires to adjust a magnitude of radial flexion of the steerable transluminal device. A position control member is operable to control tension on the pull wires to adjust a circumferential angle in which the radial flexion of the steerable transluminal device is directed.

Abstract: A cap for a medical connector, the cap including a body having a closed proximal end and an open distal end, an interior volume within the body, an elongate member comprising an antimicrobial extending from the proximal end of body axially through at least a portion of the interior volume, the elongate member, threads for securing the cap to a medical connector, and a radially inwardly facing sealing surface on the cap, the inwardly facing sealing surface located distal to the threads and providing a liquid-tight seal between the cap and the medical connector when the cap is installed on the medical connector.

Abstract: An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, and/or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. The system may also include a means to limit and/or adjust the depth of penetration of the ablative fluid into and beyond the tissue of the vessel wall. The catheter may also include structures which provide radial and/or lateral support to the guide tubes so that the guide tubes expand uniformly and maintain their position against the interior surface of the vessel wall as the sharpened injection needles are advanced to penetrate into the vessel wall.

Abstract: The present invention provides a steerable medical or surgical device, in particular a steerable catheter having one or more actuators which may be integrated into a catheter without the need for welding the actuator to the catheter, the device comprising a main shaft having a proximal end and a distal end, and at least one braided actuator coupled to the main shaft at or adjacent the distal end.

Abstract: A bolus delivery device is provided that comprises a housing and a reservoir defined by an activation dome and a reservoir seat and disposed within the housing for receipt of a volume of a fluid. The bolus delivery device further comprises a bladder disposed in the housing that is in fluid communication with the reservoir for receipt of the fluid from the reservoir; an actuator; an inlet conduit in fluid communication with the reservoir for providing the fluid to the reservoir; and an outlet conduit in fluid communication with the bladder for providing the fluid to a patient. The actuator is in operative communication with the reservoir to initiate a flow of the fluid from the reservoir to the bladder. The bladder expands as the bladder receives the fluid and contracts as the bladder dispenses the fluid. An infusion assembly including a bolus delivery device also is provided.

Abstract: Medical devices and methods for delivering fluid. The medical devices include one or more needles for delivering fluid. The methods may optionally include expanding an expandable member such as an inflatable member to expand an expandable scaffold outward toward a lumen wall. The devices may include one or both of one or more spine securing members or one or more needle alignment members.

Abstract: An adapter assembly includes a tapered connector including a central passage and a tapered outer surface for sealing with a tube or bottle. A male connector for connection to a female connector to fluidly communicate the female connector with the tube or bottle is coupled with the tapered connector. A method of forming such an adapter assembly is also disclosed.

Abstract: An infusion adapter for connection with an infusion fluid container includes a connection portion configured to engage an injection port of an infusion fluid container, and a port configured to connect to an intravenous line, with the port in fluid communication with the connection portion. The connection portion includes a retaining ring extending radially outward from the connection portion, with the retaining ring configured to securely connect the infusion adapter to the infusion fluid container to substantially prevent disconnection of the infusion adapter from the infusion fluid container once the infusion adapter is connected to the infusion fluid container. The retaining ring includes an indicator configured to provide visualization of insertion of the connection portion into an injection port of an infusion fluid container.

Abstract: In some examples, a catheter includes an expandable member configured to expand radially outward from a collapsed configuration to an expanded configuration. The expandable member is configured to be expanded and contracted in a controlled manner, e.g., in response to user actuation or automatically under the control of control circuitry of a device. For example, in some examples, control circuitry of a device can be configured to control the expandable member to expand and contract according to a predetermined expansion frequency or according to an expansion frequency determined based on a cardiac cycle of a patient.

Abstract: An occlusion catheter system includes a proximal hub having an inflation connection port and an inflation pathway. An inflation catheter member is connected to the proximal hub and has an inflation lumen. A stiffener member defines a longitudinal axis. The proximal end of the stiffener member is connected to the proximal hub. The stiffener member extends through a portion of the inflation lumen. An occlusion balloon has a proximal balloon end and a distal balloon end. A distal catheter member is positioned substantially on the longitudinal axis and is connected to the distal end of the stiffener member. An atraumatic tip is positioned on a distal end of the distal catheter member. The atraumatic tip has a substantially circular profile in a relaxed configuration. A pressure sensor is connected to the occlusion catheter system distally relative to the occlusion balloon and is connected to a processor by electrical wiring.

Abstract: An apparatus and method for the treatment of intravascular medical conditions is provided. The device comprising a handle assembly, an expandable portion defined by a plurality of struts oriented along a longitudinal axis and a tip member affixed to a distal end of the struts. The struts are moveable between a collapsed and an expanded position. A catheter tube extends from the handle assembly to the expandable portion. An elongate member is disposed within the catheter tube and is in communication with the handle assembly and the tip member.

Abstract: Example medical devices are disclosed. An example medical device includes an elongate member having a proximal end region, a distal end region and an outer surface. The medical device also includes a plurality of filaments braided together in a first braided pattern along a first braided region of the elongate member, wherein the plurality of filaments extend continuously to a second braided region along the elongate member, wherein the plurality of filaments along the second braided region form a second braided pattern different from the first braided pattern.

Abstract: A nested syringe comprising: a first chamber comprising: an inner tube extending from a base of the first chamber and defining a base opening in the base; an adapter tube in fluid communication with the inner tube via the base opening; at least one base port in the base for providing fluid communication between the adaptor tube and a first inner volume of the first chamber; a second chamber, adapted for insertion into the first chamber wherein the second chamber comprises a third port adapted to provide fluid communication between the inner tube and a second inner volume of the second chamber and adapted for preventing fluid communication between the first inner volume and the second inner volume when the second chamber is inserted into the first chamber and the inner tube penetrates the third port; and a plunger, wherein the plunger is adapted for insertion into the second chamber.

Abstract: A syringe-based device includes a housing and an actuator mechanism including a first member and a second member. The first member includes a syringe body and a plunger, the plunger being movably disposed within the syringe body. The second member includes a second member plunger seal and a valve operably and selectively coupled to the second member plunger seal such that the valve is positioned proximal of the second member plunger seal. The device also includes a first fluid reservoir and a second fluid reservoir. The device transitions from a first configuration to a second configuration in which the first type of fluid is expelled from the first fluid reservoir, to a third configuration in which the second type of fluid is expelled from the second fluid reservoir through the valve.

Abstract: A closure assembly for a medical dispenser which may include a one-piece tip cap having a flow restrictor and a removably connected sleeve disposed in surrounding relation to the flow restrictor. The tip cap further includes an access opening and an oppositely disposed closed end, wherein the flow restrictor is structured for a fluid sealing engagement with a discharge port of the medical dispenser, passing through said access opening. The closed end includes removably attached inner and outer end segments respectively formed on the flow restrictor and the sleeve and are collectively structured to define a removable connection between the flow restrictor and sleeve. A cover may be fixedly attached to the sleeve in overlying, covering relation to exterior surfaces of the inner and outer end segments.

Abstract: In general, medical sheath systems that can employ retainer devices having a plurality of channels configured to retain a sheath assembly in one or more curved configurations are described. In one embodiment, a retainer device may releasably retain a curvable tube of the sheath assembly in any of multiple curved configurations that range, for example, in selectable increments between 0° to 180°.

Abstract: Medical devices and methods for delivering fluid. The medical devices include one or more needles for delivering fluid. The methods may optionally include expanding an expandable member such as an inflatable member to expand an expandable scaffold outward toward a lumen wall. The devices may include one or both of one or more spine securing members or one or more needle alignment members.

Abstract: A cap is configured to provide antimicrobial protection to a female luer port of an intravenous device. The cap distributes an antimicrobial solution within the intraluminal surfaces of the port when the cap is connected to the port. A cap may also be designed to distribute an antimicrobial solution around the exterior surfaces of the port. Once connected to a port, the cap can form a seal that minimizes the evaporation of the antimicrobial solution from within the lumen of a port. The cap can therefore provide antimicrobial protection against another device that is connected to the port once the cap is removed.

Abstract: A rigidizing device includes an elongate flexible tube, a stiffening layer positioned radially outwards of the elongate flexible tube, an outer layer over the elongate flexible tube and the stiffening layer, and a vacuum or pressure inlet between the elongate flexible tube and the outer layer and configured to attach to a source of vacuum or pressure. The elongate flexible tube includes a first reinforcement element and a second reinforcement element. The second reinforcement element is counterwound relative to the first reinforcement element. The rigidizing device is configured to have a rigid configuration when vacuum or pressure is applied through the inlet and a flexible configuration when vacuum or pressure is not applied through the inlet.