Patents Examined by John F. Terapane
-
Patent number: 4830931Abstract: Diffusion aluminizing with chromium or silver chloride, bromide or iodide that is not significantly soluble in or reactive with water. Hydrogen can be excluded from diffusion aluminizing atmosphere when aluminizing maraging steels or other substrates sensitive to hydrogen. Aluminized iron powders can be boronized to increase their exothermic heat upon exposure to air after leaching out aluminum.Type: GrantFiled: October 3, 1983Date of Patent: May 16, 1989Assignee: Alloy Surfaces Company, Inc.Inventor: Alfonso L. Baldi
-
Patent number: 4830847Abstract: Diphosphonate-derivatized macromolecules, such as proteins, suitable for use as technetium-99m-based scanning agents and as anticalcification agents are disclosed. The scanning agents are prepared by combining Tc-99m in a +3, +4 and/or +5 oxidation state with the diphosphonate-derivatized macromolecules. Also disclosed are pharmaceutical compositions containing these diphosphonate-derivatized macromolecules and methods for scintigraphic imaging using these diphosphonate-derivatized macromolecules labeled with Tc-99m.Type: GrantFiled: June 28, 1985Date of Patent: May 16, 1989Assignee: The Procter & Gamble CompanyInventors: James J. Benedict, Charles R. Degenhardt, James W. Poser
-
Patent number: 4830841Abstract: The present invention contemplates the conversion of uranium hexafluoride with superheated steam to produce a fine, submicron, uranyl fluoride powder which is agglomerated and densified in a fluidized bed of a uranium oxide material. Thereafter, the agglomerated and densified uranyl fluoride is defluorinated and reduced in the fluidized bed to yield a fluoride containing uranium oxide material having a uranium to oxygen ratio of from about 1:2.0 to about 1:2.67. The so-produced fluoride contains uranium oxide material treated with steam and hydrogen to produce ceramic grade uranium dioxide.Type: GrantFiled: January 17, 1986Date of Patent: May 16, 1989Assignee: Advanced Nuclear Fuels CorporationInventor: Inaky J. Urza
-
Patent number: 4831182Abstract: A liquid crystal compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 represent C.sub.1-18 alkyl group, alkyl halide group or aralkyl halide, R.sup.1 may be the same as or different from R.sup.2, X is selected from --COOCH.sub.2 -- or --OCO--.Type: GrantFiled: April 23, 1987Date of Patent: May 16, 1989Assignee: Ajinomoto Co., Inc.Inventors: Ryoichi Higuchi, Takao Sakurai, Naoko Mikami, Kiriko Akaiwa, Koji Takeuchi
-
Patent number: 4828930Abstract: A method for making seamless, porous metal articles comprising:(a) rotating a mold containing a stabilized suspension of a metal particulate at a rate and for a time such that the particulate is separated from the suspension and distributed on the interior wall of the mold, thereby forming a structure conforming to the interior wall of the mold, the rate of rotation being sufficiently high that, preferably, at least about 65 Gs up to 100 Gs of centrifugal acceleration is achieved at the interior wall of the structure,(b) drying the formed structure to provide a structure having green or unsintered strength, and(c) sintering the dried structure to remove volatile material and fuse the individual particles of the particulate to each other to form the seamless, porous metal article.Metal articles in accordance with the invention have substantially uniform diameters, thicknesses and pore structurs, have Bubble Point ratios of greater than 1.5 up to 2.5, and find particular use as filters.Type: GrantFiled: November 2, 1987Date of Patent: May 9, 1989Assignee: Pall CorporationInventor: Paul C. Koehler
-
Patent number: 4829070Abstract: The invention provides compounds of the formulaD--DHC].sub.n (I)and the nontoxic pharmaceutically acceptable salt thereof, wherein D is the residue of a centrally acting drug containing at least one reactive functional group selected from the group consisting of amino, hydroxyl, mercapto, carboxyl, amide and imide, said residue being characterized by the absence of a hydrogen atom from at least one of said reactive functional groups in said drug; n is a positive integer equal to the number of said functional groups from which a hydrogen atom is absent; and [DHC] is the reduced, biooxidizable, blood-brain barrier penetratring lipoidal form of a dihydropyridine.revreaction.pyridinium salt redox carrier, said carrier comprising a bivalent radical of the formula ##STR1## wherein the alkylene group can be straight or branched and can contain 1 to 3 carbon atoms; R.sub.Type: GrantFiled: October 29, 1984Date of Patent: May 9, 1989Assignee: University of FloridaInventor: Nicholas S. Bodor
-
Patent number: 4826672Abstract: Methods and kits for incorporating a radioactive astatine isotope (particularly .sup.211 At) into an organic compound by electrophilic astatodestannylation of organostannanes.Type: GrantFiled: June 7, 1985Date of Patent: May 2, 1989Assignee: President and Fellows of Harvard CollegeInventors: Richard A. Milius, Richard M. Lambrecht, William D. Bloomer
-
Patent number: 4824733Abstract: There is described a coating providing an anti-oxidant barrier for carbon based material against oxidation at high temperature (temperature higher than 500.degree. C.), more particularly for graphite electrodes used in electric arc furnaces. The coating comprises at least a first layer of metallic titanium or titanium alloy which is applied directly on the carbon-based material, e.g. graphite, and a second layer which comprises a mixture of silicon carbide and aluminum alloy, the second layer being applied on the first layer. This coating substantially extends the life of the carbon-based material. There is also disclosed a method of producing this coating by applying the two layers onto a carbon-based material such as graphite.Type: GrantFiled: April 23, 1987Date of Patent: April 25, 1989Assignee: Canadian Patents and Development Limited/SocieteInventor: Serge Dallaire
-
Patent number: 4824537Abstract: Silicon isotopes are effectively separated by irradiating a polysilane compound or a fluoromosilane compound according to this invention with infrared laser rays. The polysilane compound is defined by the formula.Si.sub.a X.sub.b H.sub.cwhere 2.ltoreq.a.ltoreq.3, 0.ltoreq.b.ltoreq.2a+2, 2a+2=b+c and X represents a kind or kinds of halogen, and the fluoromonosilane compound is defined by the formula.SiFX.sub.1 X.sub.2 X.sub.3where X.sub.1 and X.sub.2 are selected from the group consisting of H, Cl, Br, I, F, an alkyl radical and a halogen derivative of the alkyl radical, and X.sub.3 is selected from the group consisting of H, Cl, Br, I, an alkyl radical and a halogen derivative of the alkyl radical.Type: GrantFiled: January 30, 1986Date of Patent: April 25, 1989Assignees: Rikagaku Kenkyusho, Shin-Etsu Chemical Co., Ltd.Inventors: Shigeyoshi Arai, Masatsugu Kamioka, Yo-ichi Ishikawa, Shohei Isomura, Kyoko Sugita, Takao Oshima, Tatsuhiko Honguu
-
Patent number: 4824659Abstract: An antibody or antibody fragment is modified by chemical linkage to a synthetic poly(amide/urea/thiourea) which contains a plurality of boron atoms or other functional groups, conferring upon the resultant conjugate desirable properties as a diagnostic and/or therapeutic agent. In a preferred embodiment, boron-containing groups are conjugated to the antibody/fragment such that the resultant conjugate contains 50-2000 boron atoms, with about 96% Boron-10 isotope content, to produce conjugates useful for neutron-activated radiotherapy of tumors or pathological lesions.Type: GrantFiled: June 7, 1985Date of Patent: April 25, 1989Assignee: Immunomedics, Inc.Inventor: Marion F. Hawthorne
-
Patent number: 4824663Abstract: The present invention relates to new macroemulsions which contain0.001 to 60 percent by weight of at least one active compound from the class comprising the phosphates and/or carbamates,0 to 50 percent by weight of aromatic diluents,0.001 to 20 percent by weight of polyvinyl alcohol having a mean molecular weight of between 5,000 and 150,000 and a content of acetate groups of between 2 and 30 mol %, and/or0.001 to 20 percent by weight of a nonlphenol/propylene oxide/ethylene oxide adduct of the formula ##STR1## in which X represents integers from 10 to 50 andY represents integers from 15 to 65,and/or0.001 to 20 percent by weight of ethylene oxide/propylene oxide/ethylene oxide block copolymers having a mean molecular weight of between 2,000 and 8,000 and HLB values of between 8 and 30,and water and, if appropriate, additives, andin which the oil phase is dispersed in the aqueous phase in the form of droplets having a mean particle diameter of 0.1 to 3.0 .mu.m.Type: GrantFiled: March 7, 1986Date of Patent: April 25, 1989Assignee: Bayer AktiengesellschaftInventors: Wolfgang Wirth, Heinz J. Niessen, John W. S. Goossens, Hans Schulze
-
Patent number: 4824660Abstract: A method of determining the viability of tissue in a region of an organism comprises the steps of introducing an ATP repleting agent into the region and monitoring the region to determine its effect on T1-201 distribution in the region. The capability of viable tissue to synthesize ATP and increase its ATP stores provides an indication of the viability of the tissue in the region. In a preferred embodiment of the method, ribose, which is a high energy phosphate precursor and an ATP repleting agent, is introduced into heart tissue that is being monitored by T1-201 scintigraphy. The ribose increases the rate and extent of T1-201 distribution in the heart tissue, thereby allowing the determination of viable "stunned" heart tissue. That viable tissue is distinguishable from nonviable tissue is attributed to the capability of the former to synthesize ATP and increase its ATP stores in response to the administration of the ATP repleting agent.Type: GrantFiled: June 6, 1985Date of Patent: April 25, 1989Assignee: Paul S. AngelloInventors: Debra A. Angello, Richard A. Wilson
-
Patent number: 4824607Abstract: A process for denitrating aqueous, nitric acid and salt containing waste solutions, comprises mixing the waste solution at room temperature with ethyl alcohol, and heating the mixture to at least 75.degree. C.Type: GrantFiled: November 17, 1983Date of Patent: April 25, 1989Assignee: Kernforschungszentrum Karlsruhe GmbHInventor: Klaus Gompper
-
Patent number: 4822614Abstract: A film-forming bioactive composition for control of crawling insects and the like is disclosed. Also disclosed are methods of producing and utilizing the bioactive composition. The bioactive composition comprises a water-in-oil emulsion, a lubricating agent also dispersed throughout the emulsion. The water-in-oil emulsion comprises a continuous phase, an aqueous discontinuous phase, and an emulsifier system for dispersing the discontinuous phase throughout the continuous phase. The bioactive composition of the present invention is characterized in that after particles of the instant bioactive composition have been applied to a surface, a substantial portion of the continuous and discontinuous phases will evaporate over time, leaving a residual film on the surface. Such film comprises the emulsifier system, the bioactive ingredient, and the lubricating agent.Type: GrantFiled: December 19, 1986Date of Patent: April 18, 1989Assignee: S. C. Johnson & Son, Inc.Inventor: Alejandro Rodero
-
Patent number: 4822414Abstract: Al-based alloys comprising predetermined amounts of Cr and Ti with the balance being Al and inevitable impurities. The alloys are made by powder metallurgy by which the additive elements are finely dispersed in an Al matrix. The alloys may further comprise up to 5 wt. %. of Fe.Type: GrantFiled: May 18, 1987Date of Patent: April 18, 1989Assignee: Kabushiki Kaisha Kobe Seiko ShoInventors: Katsuyuki Yoshikawa, Hidetoshi Inoue, Tsukasa Shiomi, Shojiro Oie, Mutsumi Abe
-
Patent number: 4822692Abstract: A method for making seamless, porous metal articles comprising:(a) rotating a mold containing a stabilized suspension of a metal particulate at a rate and for a time such that the particulate is separated from the suspension and distributed on the interior wall of the mold, thereby forming a structure conforming to the interior wall of the mold, the rate of rotation being sufficiently high that at least about 100 Gs of centrifugal acceleration is achieved at the interior wall of the structure,(b) drying the formed structure to provide a structure having green or unsintered strength, and(c) sintering the dried structure to remove volatile material and fuse the individual particles of the particulate to each other to form the seamless, porous metal article.Metal articles in accordance with the invention have substantially uniform diameters, thicknesses and pore structures, have Bubble Point ratios of 1.5 or less, and find particular use as filters.Type: GrantFiled: November 12, 1987Date of Patent: April 18, 1989Assignee: Pall CorporationInventor: Paul C. Koehler
-
Patent number: 4820338Abstract: A magnetic powder composition suitable for manufacturing a powder core used in a reactor or transformer connected to a semiconductor switching element, essentially consists of a powder of a soft magnetic metal or alloy or a mixture of these, an electrically insulating binder polymer for binding the powder, and a coupling agent of an organic metallic compound for coupling the powder and the binder polymer. The obtained powder core has excellent frequency characteristics of magnetic permeability, a high magnetic flux density, and a small iron loss at high frequencies.Type: GrantFiled: November 17, 1986Date of Patent: April 11, 1989Assignee: Kabushiki Kaisha ToshibaInventors: Kumi Ochiai, Hiromichi Horie, Itsuo Arima, Mikio Morita
-
Patent number: 4820442Abstract: Disclosed is a preservative composition for foodstuffs and the like, which is comprised of (i) a metal powder or a granulated product thereof, (ii) an oxidation accelerator for the metal, (iii) polyallylamine, and (iv) an optional ethanol vapor-generating member. The polyallylamine is preferably deodorized by loading a solution of polyallylamine or a salt thereof on a carrier, and heating and drying the polyallylamine-loaded carrier.Type: GrantFiled: December 22, 1986Date of Patent: April 11, 1989Assignee: Freund Industrial Co., Ltd.Inventors: Shimesu Motoyama, Shigeru Ohno, Seiichi Umeda
-
Patent number: 4820881Abstract: A process to decolorize and stabilize nitro compounds by contacting the nitro compound with an alkaline earth metal hypochlorite particulate material.Type: GrantFiled: May 24, 1988Date of Patent: April 11, 1989Assignee: W. R. Grace & Co.-Conn.Inventor: Robert J. Kupper
-
Patent number: H626Abstract: A method of synthesizing ceramic oxides using the Sol-Gel process to control particle size distribution, crystal structure and to achieve the selective incorporation of transition metals within a ceramic oxide matrix in order to produce tailored oxides with specific particle morphology and near zero expansion optical ceramics.Type: GrantFiled: August 4, 1986Date of Patent: April 4, 1989Assignee: The United States of America as represented by the Secretary of the NavyInventor: Josephine Covino