Abstract: A method for producing soluble preparations of neutral glucan polymers is disclosed. The method involves treating whole glucan particles with a unique sequence of acid and alkaline treatments to produce soluble glucan. The soluble glucan can be purified to obtain a physiologically acceptable solution of neutral glucan molecules. A soluble neutral glucan preparation is obtained which forms a clear solution at a neutral pH and is equilibrated in a pharmaceutically acceptable carrier.
Type:
Grant
Filed:
March 8, 1995
Date of Patent:
December 15, 1998
Assignee:
Alpha-Beta Technology, Inc.
Inventors:
Spiros Jamas, D. Davidson Easson, Jr., Gary R. Ostroff