Abstract: A supercritical fluid chromatograph includes a suction discharger that sucks and discharges a sample, a first sample loop connected to the suction discharger through a first flow path, a first flow path switcher that is connected to the first sample loop through a second flow path, a sample container connected to the second flow path through a third flow path when the first flow path switcher is in a first switch state, and a second flow path switcher connected to the second flow path through a fourth flow path when the first flow path switcher is in a second switch state. The fourth flow path is connected to a second sample loop when the second flow path switcher is in a third switch state, and the second sample loop is connected to an analysis flow path to which a solvent is supplied as a supercritical fluid when the second flow path switcher is in a fourth switch state.

Abstract: A heating system for medical fluid that comprises a receptacle for medical fluid to be heated, a heating element powered by a power supply inducing a leakage current (to ground) ranging between 100 and 10 ?A. The heating system further comprises an interface device (for example, an electrical insulation and thermal interface device) disposed between the heating element and the medical fluid contained in the receptacle, allowing the heating system to induce a leakage current in the medical fluid that is less than 10 ?A at the applied part.

Abstract: A peritoneal dialysis (“PD”) system includes a PD fluid pump; a disinfection loop including the PD fluid pump, the disinfection loop including PD fluid used for disinfecting the disinfection loop; and a carbon dioxide (CO2), source positioned and arranged to supply CO2 to the disinfection loop to inhibit and/or remove the production of calcium carbonate (CaCO3) during a disinfection sequence. The PD system includes a control unit configured to open a valve to allow CO2 to be supplied, wherein the control unit may use a lookup table or algorithm to determine the desired pressure or pressure increase.

Abstract: The present invention relates to a medical device, in particular a device for extracorporeal blood treatment, having an output unit for outputting system sounds for communication with a user, wherein the output unit is additionally adapted to transmit message sounds for communication with at least one other apparatus.

Abstract: The invention provides a process of purification of antibody or fusion protein from protein mixture comprising product and process related impurities. The process provides the use of hydroxyapatite chromatography for the separation of low molecular weight impurities and basic variants. In addition, invention further provides a scalable purification process to remove product and process related impurities.

Abstract: Systems and methods for performing therapeutic plasma exchange are provided. The systems and methods utilize a plasmapheresis device that includes a controller that is configured and/or programmed to monitor the amount plasma collected and initiate delivery of a therapeutic agent.

Abstract: A peritoneal dialysis system comprises a cycler including a pump actuator; a disposable set including a pumping portion operable with the pump actuator, a patient line positioned to fluidly communicate with the pumping portion, and a drain container positioned to fluidly communicate with the pumping portion; and a control unit configured to cause the pump actuator to actuate the pumping portion to (i) run a peritoneal dialysis treatment in which fresh dialysis fluid is pumped through the patient line to a patient and used dialysis fluid is pumped from the patient to the drain container, and (ii) at the end of treatment, pump the used dialysis fluid from the drain container, through the patient line, to a house drain.

Abstract: A peritoneal dialysis system comprises a cycler including a pump actuator, a patient line valve actuator, at least one supply line valve actuator, and a drain line valve actuator; and a disposable medical fluid cassette including a pumping portion configured to operate with the pump actuator, a patient line valve seat configured to operate with the patient line valve actuator, a rigid body defining a common well, at least one supply line valve seat located in the common well and configured to operate with at least one supply line valve actuator, and a drain line valve seat located in the common well and configured to operate with the drain line valve actuator.

Abstract: There is disclosed a method and system for utilizing carbon fibres for purification of rejected brine solution comprising thermally recycling carbon fibres and mechanically reducing the recycled carbon fibres, employing a chemical surface activation process for the reduced carbon fibres, resulting in chemically activated recycled carbon fibres; and exposing the activated recycled carbon fibres along with the brine solution to CO2 gas, resulting in the activated recycled carbon fibres selectively recovering contaminants from the brine solution, wherein adsorption of CO2 molecules is also performed by the activated recycled carbon fibres during the recovery. The thermal recycling of carbon fibres is done via pyrolysis and a G-S-L contact system assists in exposing the activated carbon fibres along with the brine solution to CO2 gas at varying flow rates and contact times for recovering contaminants from the brine solution.

Abstract: An agricultural processing system includes a process that uses water and produces wastewater having insoluble solids, a pump configured to receive and pressurize the wastewater from the process, and a plurality of centrifugal separators connected in parallel and configured to receive the wastewater from the pump. The separators are each configured to separate out the insoluble solids from the wastewater to produce a cleaned wastewater.

Abstract: A bioprocess fluid mixing system (3; 3?; 3?; 103; 103?), said fluid mixing system (3; 3?; 3?; 103; 103?) comprising:—at least two fluid inlets (5a, 5b, 5c, 5d, 5e), configured for providing a first fluid into the fluid mixing system through a first fluid inlet (5a) and for providing a second fluid into the fluid mixing system through a second fluid inlet (5b);—at least one valve arrangement (13a, 13b, 13c, 13a?), where a first valve arrangement (13a; 13a?) is in fluid communication with at least both the first fluid inlet (5a) and the second fluid inlet (5b);—at least two pumps (11a, 11b, 11c, 11d, 11e), where a first pump (11a) is in selective fluid communication with at least both the first and the second fluid inlets (5a, 5b) via the first valve arrangement (13a; 13a?) and a second pump (11b) is in fluid communication with at least one of the first and second fluid inlet (5b); and—a common fluid outlet (14) which is in fluid communication with both an outlet (15a) of the first pump (11a) and an outlet (15b

Abstract: A dialysis machine operable with a disposable set having at least one container, the dialysis machine including a pump actuator operable to pump dialysis fluid to and/or from the at least one container; a weigh plate positioned to support the at least one container; a plurality of operational load cells positioned to support the weigh plate; a linear actuator positioned to apply a force to the weigh plate; a calibration load cell positioned to measure the force applied by the linear actuator; and a control unit in operable communication with the operational load cells, the linear actuator and the calibration load cell, the control unit configured to cause the linear actuator to apply the force to the weigh plate, compare resulting outputs from the operational load cells and the calibration load cell, and determine a calibration factor from the comparison for offsetting future outputs from the operational load cells.

Abstract: Described herein is a method for cleaning an electrocoating bath in a continuous facility, where a skid connected to a conveying installation is conveyed through the electrocoating bath, and where the skid includes a filter medium; the filter medium is secured on the skid via at least one movable connecting element; the movable connecting element allows the orientation of the filter medium at the interface between electrocoating bath and air; and, after immersion of the skid into the electrocoating bath, during the conveying of the skid through the electrocoating bath, the filter medium is oriented at the interface between electrocoating bath and air and is drawn along the surface of the electrocoating bath. Also described herein is a skid for use in the cleaning method.

Abstract: The disclosure provides a manual blood or body fluid treatment system comprising first and second reservoirs for holding a batch of blood from a patient and a filter for performing an extracorporeal treatment on blood passing therethrough by removing waste molecules and/or fluid. The first reservoir is constructed to be displaced vertically relative to the second reservoir and vice versa, such that a height difference between the first and second reservoirs causes blood or body fluid to flow between the reservoirs due to gravity.

Abstract: Described herein are compositions and methods for performing plasmapheresis. The compositions and methods for performing plasmapheresis are innovative at least in their application towards the treatment and prevention of aging and conditions associated with aging. Plasmapheresis compositions and methods described herein are directed towards reducing or eliminating conditions associated with aging.

Abstract: Systems and devices are provided for heating an infusible liquid. The inline heater includes a fluid flow channel defined by a conduit for flowing an infusible liquid through a first portion of the conduit having a first cross-sectional dimension to a second portion of the conduit having a smaller second cross-sectional dimension. A nozzle is disposed in the first portion of the conduit. A heating element in thermal communication with an outer surface of the second portion of the conduit conducts heat through the conduit into the infusible liquid. The nozzle is positioned to spray the infusible liquid about a circumference of an inner wall of the second portion of the conduit to provide increased heat transfer from the heating element to the infusible liquid. The inline heater may be formed as a cassette for use in a dialysis machine.

Abstract: A portable platelet apheresis system can include: a whole blood inlet configured to receive whole blood; an anticoagulant source containing an anticoagulant; a mixer fluidly coupled with the whole blood inlet and anticoagulant source and configured to mix the whole blood and the anticoagulant; a whole blood sorter microfluidic network; a platelet poor outlet positioned to receive a platelet poor fraction; and a platelet concentrator outlet positioned to receive a concentrated platelet fraction. The whole blood sorter microfluidic network includes: a sorter constricted region having a first cross-sectional dimension; a sorter expansion region having a second cross-sectional dimension that is larger than the first cross-sectional dimension; at least one sorter side channel (platelet rich plasma channel) formed into a side of the sorter expansion region; and at least one sorter outlet (platelet poor plasma channel) that is downstream or medial from the at least one sorter side channel.

Abstract: Hemofilters for in vivo filtration of blood are disclosed. The hemofilters disclosed herein provide an optimal flow of blood through the filtration channels while maintaining a pressure gradient across the filtration channel walls to enhance filtration and minimize turbulence and stagnation of blood in the hemofilter.

Abstract: A new method is disclosed for extracting plasma from whose blood and metering the amount of plasma to an exact volume for dispensing into a diagnostic test, in a fully automatic and self-contained device. The device can be used in resource limited settings by unskilled users to facilitate sophisticated medical diagnostic testing outside of a hospital, clinic or laboratory.

Abstract: A mobile dialysis therapy cart includes a top shelf; a cycler compartment positioned below the top shelf, the cycler compartment sized and shaped to house an APD cycler; a fluid bag management compartment sized and shaped to house at least two fluid bags; a drain compartment positioned below the fluid bag management compartment; and a plurality of wheels. The cart may include a heating device associated with the fluid bag management compartment and/or a sanitizing light source for sanitizing a location of a disposable set associated with the fluid bags.