Patents Examined by John Kim
  • Patent number: 11000551
    Abstract: Red blood cell products and compositions are disclosed. The product includes a container made from PVC or a non-PVC material that is substantially free of a phthalate plasticizer but otherwise includes one or more non-phthalate plasticizers or extractable agents. The product includes a RBC concentrate which has been combined with an additive solution for storing the RBCs.
    Type: Grant
    Filed: May 9, 2018
    Date of Patent: May 11, 2021
    Assignee: Fenwal, Inc.
    Inventors: Katherine Radwanski, Craig L. Sandford, Kyungyoon Min, Bryan Blickhan, Daniel Lynn, Tat Mui
  • Patent number: 11000809
    Abstract: A vesicle in a liquid composition including an amphiphilic diblock copolymer of the PMOXAa-b-PDMSc-d type as vesicle membrane forming material, further including as an additive from about 0.05% to about 1% v/v of reactive end group functionalised PDMSe-f, and a transmembrane protein. The vesicle optionally includes about 1 to about 12% v/v of triblock copolymer of the PMOXAa-b-PDMSc-d-PMOXAa-b type as membrane forming material.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: May 11, 2021
    Assignee: AQUAPORIN A/S
    Inventors: Mariana Spulber, Karen Gerstandt
  • Patent number: 10987461
    Abstract: Simple-to-use systems, methods, and devices for priming replacement blood treatment devices, for swapping the blood treatment devices out, for replacing swapped-out blood treatment devices, and other related operations are described. In embodiments, a blood treatment device can be primed while a therapy is still running. When the replacement blood treatment device is needed, the therapy can be stopped momentarily (less than a minute) for the rapid and safe swap of the blood treatment device. Blood loss can be minimized. The down time from therapy can be minimized.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: April 27, 2021
    Assignee: NxStage Medical, Inc.
    Inventors: James M. Brugger, David Desouza
  • Patent number: 10980933
    Abstract: A method of collecting mononuclear cells, comprising separating whole blood into cellular components and platelets suspended in plasma, separating the platelets suspended in plasma into platelet concentrate and platelet-poor plasma, combining the cellular components with the platelet-poor plasma to form a first mixture, and separating the first mixture into mononuclear cells and at least one component.
    Type: Grant
    Filed: June 10, 2019
    Date of Patent: April 20, 2021
    Assignee: Fenwal, Inc.
    Inventors: Jonathan W. Prendergast, Lan T. Nguyen, Katherine N. Radwanski
  • Patent number: 10974208
    Abstract: Membranes comprising graphene oxide sheets and associated filter media and methods are provided. In some embodiments, a membrane may comprise graphene oxide sheets that have undergone one or more chemical treatments. The chemical treatment(s) may impart beneficial properties to the membrane, such as a relatively small d-spacing, compatibility with a broad range of environments, physical stability, and charge neutrality. For example, the graphene oxide sheets may undergo one or more chemical treatments that form chemical linkages between at least a portion of the graphene oxide sheets in the membrane. Such chemical linkages may impart a small d-spacing, broad compatibility, and/or allow relatively thick membranes to be formed. In certain embodiments, the graphene oxide sheets may undergo one or more chemical treatment that imparts relative charge neutrality to the membrane by altering the ionizability of certain functional groups.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: April 13, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Shreya H. Dave, Brent Keller, Ggoch Ddeul Han, Jeffrey C. Grossman
  • Patent number: 10974203
    Abstract: A ceramic membrane filter includes a porous substrate including cells through which a fluid flows, an intermediate membrane formed on the porous substrate, and a separation membrane formed on the intermediate membrane. In this ceramic membrane filter, the percentage of the number of cells having cracks with a size of 4 ?m or less relative to the total number of cells is 9% or less.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: April 13, 2021
    Assignee: NGK Insulators, Ltd.
    Inventors: Koji Hieda, Muneyuki Iwabuchi
  • Patent number: 10967115
    Abstract: Provided are a toxin separator and the like which are capable of selectively separating toxin present in a biological fluid by binding to protein, from the toxin and the protein. The toxin separator of the present invention also includes activated carbon of which a pore volume of pores having a pore diameter from 1.4 to 35 nm as measured by a nitrogen adsorption method is 0.06 cm3/g or greater.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: April 6, 2021
    Assignee: Kureha Corporation
    Inventors: Makoto Imaji, Kaori Kikuchi, Yoshiharu Itoh
  • Patent number: 10960361
    Abstract: Described in the present application are methods of producing silane-crosslinked polymer membranes at moderate temperatures using acid catalysts that, in certain embodiments, result in membranes with unexpectedly high permeabilities and selectivities. In certain embodiments, grafting and crosslinking of the silanes occur by immersing a preformed membrane in a solution comprising a silane and an acid catalyst. Alternatively, in certain embodiments, grafting of silanes to a polymer occurs in the presence of acid catalyst in solution and subsequent casting and drying produces crosslinked membranes. In certain embodiments, an acid catalyst is a weak acid catalyst. Also described in the present application are asymmetric crosslinked polymer membranes with porous layers. In certain embodiments, crosslinked cellulose acetate membranes have permeability up to an order of magnitude greater than the permeability of unmodified cellulose acetate membranes.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: March 30, 2021
    Assignee: Saudi Arabian Oil Company
    Inventors: Justin Tyler Vaughn, Benjamin James Sundell
  • Patent number: 10946131
    Abstract: A plasmapheresis system and a method for operating a plasmapheresis system are provided by which the volume/weight of anticoagulated plasma that is collected is optimized. In one example, a nomogram is provided that utilizes the donor's hematocrit to calculate the volume/weight of raw plasma within a plasma product having the maximum volume permitted by the FDA nomogram. In a plasmapheresis procedure having multiple collection phases followed by a reinfusion cycle in which concentrated red blood cells are returned to the donor, the volume of plasma product to be collected is calculated prior to the start of each collection cycle to account for the donor's increasing hematocrit, thus resulting in a greater total volume of plasma product to be collected during the plasmapheresis procedure.
    Type: Grant
    Filed: October 2, 2020
    Date of Patent: March 16, 2021
    Assignee: Fenwal, Inc.
    Inventors: Amit J. Patel, Samantha M. Planas, Walter T. Watts, Kyungyoon Min, Daniel R. Boggs
  • Patent number: 10940445
    Abstract: Disclosed is a membrane surface modification method. The method is applicable to a variety of hydrophobic membranes by doping selected inorganic particles. One act of the method involves the in-situ embedment of the inorganic particles onto the membrane surface by dispersing the particles in a non-solvent bath for polymer precipitation. Further membrane surface modification can be achieved by hydrothermally growing new inorganic phase on the embedded particles. The embedment of particles is for the subsequent phase growth.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: March 9, 2021
    Inventors: Kaimin Shih, Xiao-Yan Li, Xiao-Mao Wang, Tong Zhang
  • Patent number: 10933378
    Abstract: The present invention relates to novel cartridges and modules for separation of fluid mixtures, especially for gas separation, to a process for production thereof and to a method of use thereof.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: March 2, 2021
    Assignee: Evonik Fibres GmbH
    Inventors: Tymen Visser, Steven Pedersen
  • Patent number: 10926225
    Abstract: Hollow fiber cartridges and components and methods of their construction.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: February 23, 2021
    Assignee: Refine Technology, LLC
    Inventor: Jerry Shevitz
  • Patent number: 10906042
    Abstract: A new method is disclosed for extracting plasma from whole blood and metering the amount of plasma to an exact volume for dispensing into a diagnostic test, in a fully automatic and self-contained device. The device can be used in resource limited settings by unskilled users to facilitate sophisticated medical diagnostic testing outside of a hospital, clinic or laboratory.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: February 2, 2021
    Assignee: GattaCo Inc.
    Inventor: Michael Ryan McNeely
  • Patent number: 10888820
    Abstract: An osmotic membrane comprises an active layer and a composite support layer. The active layer selectively allows passage of water molecules but rejects at least some dissolved ions. The composite support layer includes a side that is bonded to the active layer and comprises an electrospun-fiber sub-layer and a phase-inversion sub-layer.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: January 12, 2021
    Assignee: Gradiant Corporation
    Inventors: Prakash Narayan Govindan, Looh Tchuin Choong
  • Patent number: 10888840
    Abstract: An object of the present invention is to provide a material which can remove an activated leukocyte-activated platelet complex with high efficiency. The present invention provides a material for removing an activated leukocyte-activated platelet complex, the material being a water-insoluble carrier to the surface of which carrier a compound(s) having a charged functional group(s) is(are) bound, wherein an extending length ratio of the surface is 4 to 7.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: January 12, 2021
    Inventors: Naotoshi Tomita, Kaoru Shimada, Hiroshi Takahashi
  • Patent number: 10881775
    Abstract: The invention relates to a dialysis machine capable of performing ultrafiltration without the need for a dedicated ultrafiltration pump. The system uses a pair of membrane flow balance pumps wherein the operation and/or the volume flow rate of the pumps can be modified during operation to bring about a net movement of dialysate either into or from the dialyser. The direction of flow of the dialysate in the dialyzer is reversible and the dialyzer can comprise two dialysate inlets, one at each end, and two dialysate outlets, one at each end.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: January 5, 2021
    Inventor: Mark Wallace
  • Patent number: 10881777
    Abstract: A blood based solute monitoring system for measuring at least one blood solute species that has a first recirculation flow path in fluid communication with a dialyzer. The first recirculation flow path is configured to allow a fluid to recirculate through a dialyzer such that the concentration of at least one solute species in the fluid becomes equilibrated to the solute species concentration of the blood in a blood compartment of the dialyzer. The blood solute monitoring system has at least one sensor to measure a fluid characteristic.
    Type: Grant
    Filed: October 9, 2018
    Date of Patent: January 5, 2021
    Assignee: Medtronic, Inc.
    Inventors: Bryant J. Pudil, Thomas E. Meyer, David B. Lura, Martin T. Gerber
  • Patent number: 10875803
    Abstract: A self-contained water system that provides single point hyper-oxygenated water delivery to a soaking vessel, part of a conventional soaking spa, is presented. The self-contained water system purifies incoming water and restructures the purified water to deliver purified, alkaline, ionized, mineral-rich, and oxygen-rich water. Dissolved oxygen concentration of the water in the soaking vessel can be controlled and maintained at a desired high concentration value, in a range of 10 mg per liter to 50 mg per liter, for water that is at a temperature ranging from 4° C. to 50° C.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: December 29, 2020
    Inventor: Kenneth J. Guoin
  • Patent number: 10864313
    Abstract: A device for removing a biological and/or chemical entity (C) from extracorporeal blood (B) is disclosed. The device has a hollow capture chamber with an inlet for the entry of the extracorporeal blood (B) and an outlet for the outflow of the extracorporeal blood (B) and a capture element inside the capture chamber having a reactant surface placed in contact with the extracorporeal blood (B) and a plurality of binding agents (A) for the biological and/or chemical entity to be removed (C) such that the biological and/or chemical entity (C), upon exiting the capture chamber, is removed from the extracorporeal blood (B) as linked to the reactant surface.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: December 15, 2020
    Inventors: Michel Rigaud, Wainer Zoli, Francesco Fabbri, Giulia Gallerani, Pietro Fici
  • Patent number: 10858269
    Abstract: Waste water is treated by contacting it with sodium to form hydrogen which is then contacted with air in a combustion chamber to produce clean water and heat.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: December 8, 2020
    Inventor: William Whitney Burch