Abstract: Described herein are compositions and methods for performing plasmapheresis. The compositions and methods for performing plasmapheresis are innovative at least in their application towards the treatment and prevention of aging and conditions associated with aging. Plasmapheresis compositions and methods described herein are directed towards reducing or eliminating conditions associated with aging.

Abstract: A filter for separating particles from a cooling liquid in a nuclear plant is presented. The filter includes at least one passage with an inner surface, an inlet end and an outlet end, wherein the at least one passage is arranged to permit through-flow of the cooling liquid in a main flow direction (MFD) from the inlet end to the outlet end. The inner surface of the at least one passage includes at least one surface section having a structured surface forming a plurality of surface portions facing the main flow direction (MFD) of the cooling liquid and being arranged to catch the particles. Also, a fuel assembly for a nuclear plant, including a filter is presented.

Abstract: A combinatorial drug delivery device is provided for delivering a predetermined selection of drug components, each of the drug components being contained in a drug vial. The device includes a plurality of modules, wherein each of the modules includes: a body having an interior volume formed to accommodate a drug vial; a cannula protruding into the interior volume, the cannula terminating at a free end, first and second openings being formed in the free end with first and second lumens extending therefrom and through the cannula; a socket located on an exterior portion of the body; a first passageway extending between, and in communication with, the socket and the first lumen; a boss protruding from an exterior portion of the body; and, a second passageway extending from, and in communication with the second lumen, the second passageway extending through the boss to terminate at an exit opening formed therein.

Abstract: In certain embodiments, the present invention is directed to a process for decontaminating water to remove per- and polyfluoroalkyl substances (PFAS), the process comprising passing contaminated water through a filter comprising at least one filtering element, wherein the filtering element comprises organic fibers; wherein the decontaminated water has a PFAS level of less than 70 ppt.

Abstract: A system for collecting plasma comprises a separator to separate whole blood from a donor into a plasma product and red blood cells, an anticoagulant line to introduce anticoagulant to the whole blood, a touchscreen, and a controller. The controller is configured to receive donor parameters electronically from a donor management system. The controller is configured to use a target volume for plasma product and/or raw plasma which is based at least in part on donor height and weight used to calculate total donor blood volume, the target volume for plasma product and/or raw plasma based on the total donor blood volume. The controller is configured to control the system to operate at least three draw and return phases to withdraw whole blood from a donor and separate the whole blood into the plasma product and the red blood cells and to return the red blood cells to the donor.

Abstract: The present disclosure relates to the extraction of lithium from liquid resources such as natural and synthetic brines, leachate solutions from clays and minerals, and recycled products.

Abstract: A filter element mounting structure comprises a switch member arranged on a shell, a limiting member and a driving mechanism; the driving mechanism is arranged on the shell, the limiting member is connected with the driving mechanism, a locking groove is formed on a filter element, the limiting member comprises a plurality of locking positions comprising a first locking position, a second locking position and a third locking position; when the limiting member is in the first locking position, the filter element is mounted in the shell, when the filter element is mounted in the shell, the switch member is touched, and the driving mechanism controls the limiting member to move to the second locking position and lock the filter element; and when the driving mechanism drives the limiting member to move to the third locking position, the limiting member provides an ejecting force to eject the filter element.

Abstract: A blood treatment method includes the steps of inducing flow of a patient's blood through a blood treatment device inlet and outlet in fluid connection to the circulatory system of the patient. Metastatic deoxyribonucleic acid (DNA) contained within patient blood is destroyed by passing a patient's blood over a bioreactor surface having attached or immobilized deoxyribonuclease 1 (DNase 1) enzyme. The blood treatment device which consists of a bioreactor containing immobilized DNase 1, enables continuous treatment of a patient's blood and increases the effective concentration of DNase 1 in a patient's bloodstream to convert metastasizing cancer DNA in blood into non-oncogenic nucleotide fragments in vivo without adding any chemicals to the blood of the patient.

Abstract: A detoxification method for treating sepsis, microbial infections, and other inflammatory conditions includes the steps of inducing flow of patient blood through a blood treatment device consisting of a bioreactor inlet and outlet in fluid connection to the circulatory system of a patient. Biological agents including lipopolysaccharide (LPS) and extracellular adenosine triphosphate (ATP) contained within patient blood can be irreversibly detoxified by passage of patient blood over a bioreactor surface having attached or immobilized alkaline phosphatase enzymes and acyloxyacyl hydrolase enzyme, with the bioreactor being contained within the blood treatment device. The method uses continuous treatment of a patient's blood to convert LPS and extracellular ATP in blood into inhibitors of inflammation in vivo without adding any chemicals to the bloodstream of the patient.

Abstract: The present invention generally relates to hemodialysis and similar dialysis systems, including a variety of systems and methods that would make hemodialysis more efficient, easier, and/or more affordable. One aspect of the invention is generally directed to new fluid circuits for fluid flow. In one set of embodiments, a hemodialysis system may include a blood flow path and a dialysate flow path, where the dialysate flow path includes one or more of a balancing circuit, a mixing circuit, and/or a directing circuit. Preparation of dialysate by the preparation circuit, in some instances, may be decoupled from patient dialysis. In some cases, the circuits are defined, at least partially, within one or more cassettes, optionally interconnected with conduits, pumps, or the like. In one embodiment, the fluid circuit and/or the various fluid flow paths may be at least partially isolated, spatially and/or thermally, from electrical components of the hemodialysis system.

Abstract: The present invention relates to an apparatus for performing an automated peritoneal dialysis treatment on a patient, the apparatus comprising: a first dialysis fluid port for receiving a first dialysis fluid having a first composition, which is determined by the concentrations of a set of first dialysis fluid constituents; a dialysis fluid line system connecting the first dialysis fluid port to a patient terminal; at least one dialysis fluid pump acting on the dialysis fluid line system and configured to convey the first dialysis fluid from the first dialysis fluid port to the patient terminal; and a control unit operably connected to the at least one pump; wherein the apparatus further comprises a second dialysis fluid port for receiving a second dialysis fluid having a second composition, which is determined by the concentrations of a set of second dialysis fluid constituents.

Abstract: There is provided a method in a device of a cellular network, the method comprising: receiving a user plane data from a source network node of the cellular network; detecting that at least one quality condition with respect to the user plane data transfer is met; and in response to the detecting that the at least one quality condition is met, causing a transmission of an indication for a data forwarding or duplication to a target network node of the cellular network or to the source network node, the data forwarding or duplication causing the source network node to forward or duplicate a user plane data of the device to the target network node.

Abstract: A blood circuit assembly for a dialysis unit may include an organizing tray, a pair of pneumatic pumps mounted to the organizing tray for circulating blood received from a patient through a circuit including a dialyzer unit and returned to the patient, an air trap mounted to the organizing tray arranged to remove air from blood circulating in the circuit, a pair of dialyzer connections arranged to connect to the inlet and outlet of a dialyzer unit, and a pair of blood line connectors, one inlet blood line connector for receiving blood from the patient and providing blood to the pneumatic pumps and the other outlet blood line connector for returning blood to the patient.

Abstract: The invention relates to an apparatus for carrying out a peritoneal dialysis treatment comprising a reservoir for fresh dialysis fluid, a connector for connecting to a peritoneal catheter of a patient, a drain for consumed dialysis fluid, and a control unit connected to actuators, wherein the apparatus is configured to carry out a plurality of consecutive inflow-dwell-outflow cycles for a treatment on the basis of a prescription stored in the control unit, in which inflow-dwell-outflow cycles dialysis fluid is supplied to the patient from the reservoir and is led off through the outflow again after the elapse of a specific dwell time in the peritoneum of the patient, and wherein the apparatus is further configured to already replace a portion of the dialysis fluid present in the peritoneum of the patient with fresh dialysis fluid from the reservoir before the elapse of the dwell time in at least one cycle if, in at least one preceding cycle, the volume of fresh dialysis fluid provided in accordance with the p

Abstract: Provided is a chamber configuration for a reverse flow centrifuge, and a reverse flow centrifuge system configured for low fluid volume and small radius rotation. The compact reverse flow centrifuge system has a reusable subsystem and a single use replaceable subsystem. The replaceable subsystem comprises a separation chamber, fluid delivery manifold and rotational mounting connecting the separation chamber to the fluid manifold. The single use replaceable subsystem provides a closed environment for execution of reverse flow centrifugation processes. The separation chamber has a substantially conical fluid enclosure portion connected to a neck portion, and a dip tube extends centrally through the conical fluid enclosure to provide a fluid path to the tip of the conical fluid enclosure.

Abstract: Disclosed is a water purification, sterilization and disinfection lamp. The lamp includes a lampshade, a base and a cylinder for storing slow-release chlorine tablets. A circuit board and a battery electrically connected with the circuit board are arranged on the base. A solar panel is installed on a surface of the lampshade. The base is covered with the lampshade to form sealed connection. The solar panel is electrically connected with the circuit board. At least one lamp bead is assembled on the circuit board. The irradiation direction of the lamp bead faces the direction of the lampshade.

Abstract: A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

Abstract: A medical fluid container preparation system includes: a conveyor for conveying the medical fluid container, a water injector located along the conveyor, a mechanism for carrying the water injector towards and away from the medical fluid container; a sensor positioned and arranged to determine a location of the medical fluid container moving along the conveyor, and a control unit configured to read an output from the sensor and to cause (i) the mechanism to move the water injector towards the medical fluid container an amount based upon the location of the medical fluid container obtained from the sensor output and (ii) the water injector to inject a volume of water between the medical fluid container and an overpouch into which the medical fluid container is placed.

Abstract: A blood purification device includes a chamber, a liquid feed line, an air introduction unit, a liquid level adjustment unit, and a control unit. The chamber is provided on a blood circuit for extracorporeally circulating patient's blood and introduces purified plasma obtained by purifying plasma separated by a plasma separator provided on the blood circuit, or a replenishing liquid for replenishing the plasma separated by the plasma separator, into the blood circuit. The liquid feed line is capable of sending the purified plasma or the replenishing liquid to the chamber. The air introduction unit is capable of introducing air into the liquid feed line. The liquid level adjustment unit is capable of adjusting a liquid level height in the chamber.

Abstract: A filter for a water cooler includes a housing having a surface and a cavity with cavity ports. The filter end is adapted to be received in the housing. The filter end includes a cylindrical base having a surface and a neck extending from the surface. The neck has filter ports and a side surface. The side surface has oppositely directed axially extending elongated protrusions configured to be received in channels in the housing. The base surface includes a complex set of protrusions which are adapted to be received in a similarly configured set of recesses in the housing surface. The protrusions/recesses may take the form of letters, numbers or symbols. The filter end is be fully seated in the housing in bayonet-type fashion to connect the filter ports and the housing ports o permit water to flow through the filter from the water supply to the water cooler.