Abstract: Viral and bacterial contaminants present in biological solutions are inactivated by mixing one of a novel class of photosensitizer with said solution and irradiating the mixture.

Abstract: A method for bioassaying for metabolic activation of toxicants from a xenobiotic compound by a metabolic enzyme system includes incubating the xenobiotic compound with a metabolic enzyme system known to produce toxicants during normal metabolic degradation processes and with a mitochondrial membrane preparation competent for enzymatic electron transfer. The production of a toxicant has a detrimental effect upon the electron transfer activity of the mitochondrial membrane preparation which can readily be assayed by observing changes in concentration of a selected redox indicator.

Abstract: A method for performing boron neutron capture therapy for the treatment of tumors is disclosed. The method includes administering to a patient an iodinated sulfidohydroborane, a boron-10-containing compound. The site of the tumor is localized by visualizing the increased concentration of the iodine labelled compound at the tumor. The targeted tumor is then irradiated with a beam of neutrons having an energy distribution effective for neutron capture. Destruction of the tumor occurs due to high LET particle irradiation of the tissue secondary to the incident neutrons being captured by the boron-10 nuclei. Iodinated sulfidohydroboranes are disclosed which are especially suitable for the method of the invention. In a preferred embodiment, a compound having the formula Na.sub.4 B.sub.12 I.sub.11 SSB.sub.12 I.sub.11, or another pharmaceutically acceptable salt of the compound, may be administered to a cancer patient for boron neutron capture therapy.

Abstract: Polyurethane dispersions based on reaction products from (A) bismethylolated urethanes having at least 2 urethane groups and (B) polyhydroxyl compounds which contain groups which are capable of ion formation, these groups being present in neutralized form, and a process for the preparation thereof. The use of the dispersions for the surface-coating of metal, plastics, glass, leather and paper.