Abstract: Disclosed are interleukin-6 receptor agonists. These receptor agonists were enerated by mutating amino acid positions 175, 176, 177, 181, and/or 183 of human interleukin-6.
Type:
Grant
Filed:
December 4, 1995
Date of Patent:
April 6, 1999
Assignee:
Istituto di Ricerche di Biologica Molecolare P. Angeletti S.p.A.