Patents Examined by John Peabody
  • Patent number: 5298034
    Abstract: Pulverulent dye preparations useful for preparing printing inks or finishes comprise one or more solvent dyes and an auxiliary selected from the group consisting of alkyl vinyl ethers, primary, secondary or tertiary alkylamines, polybutylene glycols and addition products of ethylene oxide with polybutylene glycols.
    Type: Grant
    Filed: November 30, 1992
    Date of Patent: March 29, 1994
    Assignee: BASF Aktiengesellschaft
    Inventors: Klaus Bast, Ronald Sawa, Wolfgang Keil
  • Patent number: 5296508
    Abstract: The invention relates to novel farnesylated tetrahydro-naphthalenols, that inhibit HMGR activity which results in a decrease in serum total cholesterol, a decrease in LDL cholesterol levels, and inhibition of LDL oxidation. The farnesylated tetrahydro-naphthalenols of the present invention are thus useful for cholesterol/lipid lowering in cases of hypercholesterolemia, hyperlipidemia, and atherosclerosis.
    Type: Grant
    Filed: December 23, 1992
    Date of Patent: March 22, 1994
    Assignee: Bristol-Myers Squibb Company
    Inventor: Bradley C. Pearce
  • Patent number: 5288929
    Abstract: A method for removing, condensing and collecting propellants, e.g. chlorofluoro-carbons (CFCs) in an environmentally friendly manner from foam materials, e.g. insulant materials from old (discarded) refrigerators, district heating tubes and other materials for which the method is suitable.
    Type: Grant
    Filed: February 12, 1992
    Date of Patent: February 22, 1994
    Assignee: L&E Holding ApS
    Inventor: Lau O. Voers
  • Patent number: 5284962
    Abstract: A continuous process employing at least two reaction stages for manufacturing pesticides from methyl isocyanate and oxime or phenol reactants in water.
    Type: Grant
    Filed: October 9, 1992
    Date of Patent: February 8, 1994
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Terence A. Rensi
  • Patent number: 5284866
    Abstract: A compound isolated from Eupricillium brefeldionum having the structure: ##STR1## is a useful antitumor agent.
    Type: Grant
    Filed: October 5, 1992
    Date of Patent: February 8, 1994
    Assignee: Bristol-Myers Squibb Company
    Inventors: Friedrich Mayerl, Xiaohua Huang, Qi Gao
  • Patent number: 5284857
    Abstract: Substituted thienopyrans and processes for preparing the thienopyrans are disclosed. The thienopyrans are useful as antihypertensive agents; antianginals are peripheral antivasoconstrictive agents.
    Type: Grant
    Filed: December 21, 1990
    Date of Patent: February 8, 1994
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Jeffery B. Press, Pauline Sanfilippo, James J. McNally, Robert Falotico
  • Patent number: 5281610
    Abstract: Disclosed is a pyrazolonaphthyridine compound represented by the formula: ##STR1## wherein R.sup.1 is represents hydrogen, lower alkyl, aralkyl, or substituted or unsubstituted aryl, R.sup.2 represents hydrogen, lower alkyl, thienyl, substituted or unsubsutituted aryl, hydroxy or amino, or a pharmaceutically acceptable salt thereof.The compound possesses antiinflammatory effect, immunosuppressive effect, broncho-dilatory effect and hair growth-stimulative effect.
    Type: Grant
    Filed: December 18, 1992
    Date of Patent: January 25, 1994
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Fumio Suzuki, Takashi Kawakita, Takeshi Kuroda, Kenji Ohmori, Hiroshi Nakajima, Toshikazu Kamiya, Tatsuya Tamaoki
  • Patent number: 5280115
    Abstract: Compositions of matter comprising nitro-substituted metal complexes of porphyrins are catalysts for the oxidation of alkanes. The metal is iron, chromium, manganese, ruthenium, copper or cobalt. The porphyrin ring has nitro groups attached thereto in meso and/or .beta.-pyrrolic positions.
    Type: Grant
    Filed: June 2, 1992
    Date of Patent: January 18, 1994
    Assignee: Sun Company, Inc. (R&M)
    Inventors: Paul E. Ellis, Jr., James E. Lyons
  • Patent number: 5278181
    Abstract: Soluble alkyl [5-(amino (phenyl)methyl)-2H-benzimidazol-2-yl]carbamates, their enantiomorphic forms, and acid addition salts thereof are well absorbed and possess curative anthelmintic activity, especially against filarial worms, when administered orally or parenterally. Pharmaceutical compositions containing the compounds and methods of employing the compounds in methods of treating helminth infections in mammals are also disclosed, together with methods of synthesis.
    Type: Grant
    Filed: May 12, 1992
    Date of Patent: January 11, 1994
    Assignee: Board of Regents Acting on Behalf of the University of Michigan
    Inventors: Leroy B. Townsend, Dean S. Wise, Siya Ram
  • Patent number: 5278186
    Abstract: A chromene derivative of the formula (I) ##STR1## wherein each ring of A and B can have one or more substituents; X is an oxygen atom or sulfur atom, Y is an oxygen or sulfur atom or H.sub.2, Z is a bond, --NH-- or a saturated or unsaturated lower alkylene group and R is a hydrocarbon radical which is unsubstituted or substituted, or its salt, which is useful as a drug for atherosclerosis.
    Type: Grant
    Filed: April 2, 1991
    Date of Patent: January 11, 1994
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Kanji Meguro, Hiroyuki Tawada, Hitoshi Ikeda
  • Patent number: 5278168
    Abstract: Biological applications of synthetic and natural alkaloids derived from the tunicate Eudistoma sp. are disclosed. A method regulating cell growth includes contacting one or more cells with an effective concentration of a compound for regulating cell growth. These compounds include: Segoline A, Segoline B, Isosegoline A, Norosegoline, Debromoshermilamine, Eilatin, 4-methylpyrido[2,3,4-kl] acridine, pyrido[2,3,4-kl]acridine, 1-acetyl-2,6-dimethylpyrido[2,3,4-kl]acridine, and derivatives and combinations of these compounds. An effective concentration range for using these compounds can range from approximately 0.1 .mu.M to 100 .mu.M. The effective concentration range for Eilatin, the most potent of these compounds is from 0.01 .mu.M to 0.99 .mu.M, and the effective concentration range for the other compounds of the present invention is from about 1.0 .mu.M to 100 .mu.M.
    Type: Grant
    Filed: August 3, 1992
    Date of Patent: January 11, 1994
    Assignee: The Research Foundation of State Univeristy of New York
    Inventors: Ilan Spector, Nava R. Shochet, Yoel Kashman, Amira Rudi
  • Patent number: 5278002
    Abstract: A protective and at least in part heat-insulating cover for a battery, especially an automobile battery disposed in an automobile, having a pleasing appearance, and having a molded, rigid plastic support with at least a top wall and side walls, which walls are sufficiently rigid so as to be self supporting. Heat insulation is disposed on at least a portion of at least one wall and an envelope of plastic material encloses the insulation. Attachments attach the envelope to at least a portion of at least one wall.
    Type: Grant
    Filed: September 22, 1992
    Date of Patent: January 11, 1994
    Assignee: Lydall, Inc.
    Inventor: John J. Hiers
  • Patent number: 5273997
    Abstract: The invention provides compounds of general formula ##STR1## wherein m is 0 or 1; each of R.sup.1 and R.sup.2, and R.sup.3 and R.sup.4 if present, independently represents a hydrogen or halogen atom or an optionally substituted alkyl, cycloalkyl or aryl group, or R.sup.1 and R.sup.2 together or R.sup.3 and R.sup.4 together represent an optionally substituted alkylene chain; X represents a cyano group, a group --COOH or a salt, ester or amido derivative thereof; Y represents an alkyl group or a halogen atom; and n represents 0, 1, 2 or 3; a process for their preparation; compositions containing such compounds and their use as fungicides.
    Type: Grant
    Filed: June 12, 1992
    Date of Patent: December 28, 1993
    Assignee: Shell Research Limited
    Inventors: Thomas W. Naisby, William W. Wood, Werner E. J. Simon
  • Patent number: 5273978
    Abstract: The present invention provides an optically active isoindoline derivative represented by the formula: ##STR1## which is useful as an improving, therapeutic and preventive agent for anxiety-associated nervous symptoms, and an intermediate for synthesis thereof.
    Type: Grant
    Filed: December 17, 1992
    Date of Patent: December 28, 1993
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Giichi Goto, Naohisa Fukuda
  • Patent number: 5272172
    Abstract: Iridoid derivatives synthesized using genipin, which is an aglycon of geniposide, as the starting material are useful as an anti-hyperlipemia agent and as a cholagogue.
    Type: Grant
    Filed: August 6, 1992
    Date of Patent: December 21, 1993
    Assignee: Tsumura & Co.
    Inventors: Yuuichi Fujii, Ichiro Arai, Akira Hatta, Akemi Tatsugi, Hiroshi Mitsuhashi, Mieko Mitsuhashi, Hiroyuki Mitsuhashi, Tomoyuki Mitsuhashi, Masaharu Kigawa
  • Patent number: 5268504
    Abstract: Disclosed is a process for increasing the selectivity in converting sulfates to sulfonates following ethoxylation and sulfation of alcohols. It is demonstrated that minimization of unethoxylated and monoethoxylated alcohols before the sulfation step will substantially reduce hydration to alcohols and increase the selectivity of the subsequent sulfonation step.
    Type: Grant
    Filed: July 28, 1992
    Date of Patent: December 7, 1993
    Assignee: Exxon Production Research Company
    Inventor: Kenneth M. Webber
  • Patent number: 5266077
    Abstract: A method of tinting an unhydrated contact lens involves the steps of providing an unhydrated contact lens; providing a dyestuff solution; providing a printing block comprising a hydrophilic polymer material containing a dye complexing agent capable of noncovalently bonding the dyestuff; placing the dyestuff solution onto the printing block; contacting the unhydrated contact lens and the printing block for a time sufficient to allow the dyestuff solution to diffuse to the lens; and removing the lens from the printing block.
    Type: Grant
    Filed: November 9, 1992
    Date of Patent: November 30, 1993
    Assignee: Ciba-Geigy Corporation
    Inventors: Richard D. Auten, Robert A. Janssen, Leslie F. Stebbins, Richard C. Turek
  • Patent number: 5266699
    Abstract: The compounds of the formula I ##STR1## in which Y and Y.sub.1 are each, independently of one another, O, S, NH or N-alkyl, N-cycloalkyl,N-phenyl or N-benzyl, or Y and Y.sub.1 are together N-alkylene-N,R and R.sub.1 are each, independently of one another, H, alkyl, cycloalkyl, aralkyl or aryl,R.sub.2 and R.sub.3 are each, independently of one another, H, or R.sub.2 forms, together with R.sub.6 and the N and C atoms linking them, a 5- or 6-membered ring and R.sub.3 is H, or R.sub.3 forms, together with R.sub.7 and the N and C atoms linking them, a 5- or 6-membered ring and R.sub.2 is H,R.sub.4 and R.sub.5 are each, independently of one another, H, or R.sub.4 forms, together with R.sub.8 and the N and C atoms linking them, a 5- or 6-membered ring and R.sub.5 is H, or R.sub.5 forms, together with R.sub.9 and the N and C atoms linking them, a 5- or 6-membered ring and R.sub.4 is H,R.sub.6, R.sub.7, R.sub.8 and R.sub.9 are each, independently of one another, H, alkyl, cycloalkyl, aralkyl or aryl, or R.sub.6 and R.
    Type: Grant
    Filed: October 26, 1992
    Date of Patent: November 30, 1993
    Assignee: Ciba-Geigy Corporation
    Inventors: Rudolf Naef, Beat Schmidhalter, Hanspeter Preiswerk
  • Patent number: 5262044
    Abstract: A process for upgrading a hydrocarbonaceous feedstock which process included separating the feedstock in the presence of hydrogen at elevated temperature and a partial hydrogen pressure greater than 50 bar into a high boiling fraction and a low boiling fraction and subjecting at least part of the low boiling fraction substantially boiling in the gasoline range to a hydrotreating step under substantially the same conditions as prevailing in the separation step, and recovering from the hydrotreating step a product substantially boiling in the gasoline range and being of improved quality.
    Type: Grant
    Filed: September 8, 1992
    Date of Patent: November 16, 1993
    Assignee: Shell Oil Company
    Inventors: Tom Huizinga, Gerardus L. B. Thielemans
  • Patent number: 5260459
    Abstract: The cyclic Isolongifolanone ketals of the general formula A wherein the wavy lines mean .alpha. and .beta.-configuration and R,R' mean radicals of hydrogen, methyl or ethyl, are new. With preference they are used either as odorants or as components of perfume compositions. They are manufactured from Isolongifolene which is itself produced from Longifolene as is well known. Isolongifolene is oxydized to Isolongifolene-3-on and this is reacted with aliphatic 1,2-diols in apolar solvents with the separation of water.
    Type: Grant
    Filed: November 18, 1992
    Date of Patent: November 9, 1993
    Inventors: Ernst-Joachim Brunke, Dietmar Schatkowski