Patents Examined by John Uem
  • Acid-labile subunit als of insulin-like growth factor binding proteincomplex
    Patent number: 5849687
    Abstract: An acid-labile protein is described that, when incubated with the 53-Kd acid-stable protein occupied by IGF, converts it to a high molecular weight complex, corresponding to the in vivo form of IGF. This protein is called the acid-labile subunit (ALS) of IGF binding protein complex and is provided in biologically pure form. ALS is useful in treating wounds and promoting cellular growth. The nucleic acid encoding ALS, antibodies binding thereto, and fragments thereof are also disclosed.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: December 15, 1998
    Assignee: Genetech, Inc.
    Inventor: Robert Charles Baxter