Patents Examined by John Weber
  • Patent number: 7416843
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Grant
    Filed: January 14, 2005
    Date of Patent: August 26, 2008
    Assignee: University of South Florida
    Inventors: Matt Ewert, Phil Amuso, Andrew Cannons
  • Patent number: 7112568
    Abstract: The present invention discloses novel anti-allergic complex molecules, and in particular, peptidic or peptidomimetic molecules, comprising a first part which is competent for cell penetration and a second part which is able to reduce or abolish mast cell degranulation, in particular to reduce or abolish allergy mediators, including histamine secretion from mast cells and protein kinase activation, wherein the first part is connected to the second part via a linker or a direct bond that creates a conformational constraint by forming a bend or turn.
    Type: Grant
    Filed: June 20, 2003
    Date of Patent: September 26, 2006
    Assignee: Ramot At Tel Aviv University Ltd.
    Inventors: Ronit Eisenberg, Tamar Raz
  • Patent number: 7087728
    Abstract: The present invention relates to the field of carbohydrate crosslinked glycoprotein crystals. Advantageously, such crosslinked glycoprotein crystals display stability to harsh environmental conditions, while maintaining the structural and functional integrity of the glycoprotein backbone. According to one embodiment, this invention relates to methods for concentrating proteins that have been modified by carbohydrates and for releasing their activity at controlled rates. This invention also provides methods for producing carbohydrate crosslinked glycoprotein crystals and methods for using them in pharmaceutical formulations, vaccines, immunotherapeutics, personal care compositions, including cosmetics, veterinary pharmaceutical compositions and vaccines, foods, feeds, diagnostics, cleaning agents, including detergents and decontamination formulations.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: August 8, 2006
    Assignee: Altus Pharmaceuticals Inc.
    Inventors: Alexey L Margolin, Chandrika P Govardhan, Kalevi J Visuri, Sinikka S Uotila