Abstract: The invention relates to a system and method for performing a laser Doppler flowmetry, LDF, measurement. The system comprises a coherent light source, a photodetector and one or more processors. The photodetector generates an output signal. The processor(s) determines a selected frequency range for computing an LDF signal. A spectrum of the photodetector output signal is computed for a series of time intervals, thereby obtaining a series of spectra. A measure of the amount of physiological information in the spectra is computed for a number of different frequencies. The selected frequency range is determined as the range of frequencies for which the computed measure of amount of physiological information fulfills a predetermined criterion. The processor(s) compute an LDF signal using the selected frequency range, and output the LDF signal.

Abstract: A device, and methods for using said device, for inserting a marker into a patient's body. The device may comprise a retention mechanism to hold the device in an first, undeployed, state. The device may be inserted into a patient's body in the first state, transitioned by the user into a second state wherein the retention mechanism is overcome, and then transition the device into a third state to deliver a marker to a precise location. The device may then be removed from the patient's body.

Abstract: This invention relates generally to an ultrasound device configured to generate a frustum-shaped beam capable of fragmenting a plurality of biomineralizations located within a patient's body in combination with synthetic cavitation nuclei. The ultrasound device includes a transducer assembly comprising a plurality of ultrasound transducer elements, and a multi-channel amplifier circuit. Each channel of the multi-channel amplifier circuit is configured to actuate a distinct subset of the plurality of transducer elements. The multi-channel amplifier circuit is configured to operate in each of a plurality of states, each state of comprising a set of frequencies at which each channel of the multi-channel amplifier circuit is configured to actuate the distinct subset of transducer elements. The multi-channel amplifier circuit is further configured to switch between the plurality of states, thereby causing the plurality of ultrasound transducer elements to produce a frustum-shaped beam.

Abstract: Methods and systems are provided for determining diagnostic-scan parameters for a magnetic resonance (MR) diagnostic-scan, from MR calibration images, enabling acquisition of high-resolution diagnostic images of one or more anatomical regions of interest, while bypassing acquisition of localizer images, increasing a speed and efficiency of MR diagnostic-scanning. In one embodiment, a method for a magnetic resonance imaging (MRI) system comprises, acquiring a magnetic resonance (MR) calibration image of an imaging subject, mapping the MR calibration image to a landmark map using a trained deep neural network, determining one or more diagnostic-scan parameters based on the landmark map, acquiring an MR diagnostic image according to the diagnostic-scan parameters, and displaying the MR diagnostic image via a display device.

Abstract: Provided herein are methods of analyzing tissue using a magnetic resonance imaging (MRI) compatible tissue analysis device that includes radio-frequency (RF) tracking and imaging elements. Related kits, systems, and computer program products are also provided.

Abstract: A method is provided for determining a movement-corrected B1 field map on contrast medium injection, wherein before the injection, a B1 field map is determined. Following the contrast medium administration, a position change is determined at the position at which the B1 field map was determined. With the position change and the B1 field map, the movement-corrected B1 field map is determined.

Abstract: In one embodiment, a biological information monitoring apparatus includes: an antenna assembly including at least one antenna, the antenna assembly being disposed close to an object; a signal generator configured to generate a radio-frequency (RF) signal; and a displacement detection circuit configured to detect a physical displacement of the object based on the RF signal, wherein the at least one antenna includes: a dipole antenna having a feeding point to be supplied with the RF signal, the feeding point being positioned in a center of the dipole antenna; a coaxial line configured to supply the RF signal to the feeding point; and a conductor element that has a ¼ wavelength and is short-circuited on one end to an outer conductor of the coaxial line.

Abstract: An association of a pre-operative plan and tracked position and orientation of a surgical instrument relative patient anatomy in a navigation system is generated. The pre-operative plan includes a virtual representation of the patient anatomy data. Position and orientation of the patient anatomy as well as position and orientation of the surgical instrument within the navigation system is obtained. A virtual representation of the surgical instrument relative the virtual representation of the patient anatomy data is generated in multiple orientations in separate parts of a split window. A system with a tracker comprising a tracker interface for attaching the tracker to the instrument includes a surgical navigation module for generating the virtual representation in a split window.

Abstract: A method of determining a location of an optical fibre positioned at least partially inside a scattering medium, the method comprises transmitting pulsed light into the scattering medium, receiving, by a detector, photons of the pulsed light that have passed through the scattering medium, selecting signals corresponding to some of the received photons, wherein the selecting is based on a time of arrival of the received photons; and determining a location of the optical fibre based on the selected signals.

Abstract: This brain function measurement device (100) includes a brain blood flow information acquisition unit (1) that acquires brain blood flow information (d1) of a subject (P), a brain function information acquisition unit (30) that acquires brain function correlation information (d3) indicating a relative change in a correlation between respective portions of the brain acquired on the basis of the brain blood flow information measured in a plurality of portions of a brain before and after a task is presented, and a brain function image generation unit (7) that generates a first brain function image (20) in which a relative position of each measurement position (23) for the brain blood flow information and the measurement position at which the correlation acquired on the basis of the brain function correlation information has changed are visually recognizable.

Abstract: A patient marker couples to an anchoring device via a base having a base axis, base connections and a first indicator. The marker includes: an adapter having a first surface with connections configured to mate with the base connections, and a second surface with connections congruent with the base connections, and at least one second indicator. The marker includes an alignment target, having a target region with an alignment pattern, and a socket connected to the target region with socket connections congruent with the first surface connections. In a first configuration the socket couples to the base by mating the first surface connections with the base connections and mating the socket connections with the second surface connections. In a second configuration, the socket fits onto the base by mating the socket connections with the base connections. One of the indicators indicates a target orientation angle about the base axis.

Abstract: Disclosed herein is a method for discriminating sacroiliitis by using sacroiliac joint MR images, implemented by one or more processors of a computing device, the method comprising the steps of: collecting MR images related to the sacroiliac joint and preprocessing the collected MR images to generate training data; training a bone marrow edema discrimination model by using the generated training data; and using the trained bone marrow edema discrimination model to determine the presence of sacroiliitis from MR images related to the patient's sacroiliac joint.

Abstract: An ultrasound diagnostic apparatus (1) includes an ultrasound probe (2); an image acquisition unit that generates an ultrasound image by performing transmission and reception of an ultrasound beam with respect to a subject using the ultrasound probe (2); and an initial condition setting unit (25) that sets a basic sound speed value for generating the ultrasound image of a breast of the subject on the basis of a ratio of mammary glands in the breast, which is calculated by analyzing a radiation image in which the breast is imaged, in which the image acquisition unit generates the ultrasound image of the breast using the basic sound speed value.

Abstract: An ultrasound diagnostic apparatus 1 includes a display unit 8, an operating unit 15, a measurement position designation reception unit 14 that receives designation of a measurement position on an ultrasound image from a user through the operating unit 15, a measurement target recognition unit 9 that recognizes a measurement target included in the ultrasound image of a recognition range decided based on the received measurement position, a measurement algorithm setting unit 12 that sets a measurement algorithm based on the recognized measurement target, and a measurement unit 10 that measures the measurement target based on the set measurement algorithm and displays a measurement result on the display unit 8.

Abstract: A harmonization system for a brain activity classifier harmonizing brain measurement data obtained at a plurality of sites to realize a discrimination process based on brain functional imaging: obtains data, for a plurality of traveling subjects as common objects of measurements at each of the plurality of measurement sites, resulting from measurements of brain activities of a predetermined plurality of brain regions of each of the traveling subjects; calculates, for each of the traveling subjects, prescribed elements of a brain functional connectivity matrix representing the temporal correlation of brain activities of a set of the plurality of brain regions; using a generalized linear mixed model, calculates measurement bias data 3108 for each element of the brain functional connectivity matrix, as a fixed effect at each measurement site with respect to an average of the corresponding element across the plurality of measurement sites and across the plurality of traveling subjects; and thereby executes a harm

Abstract: Disclosed are a three-dimensional ultrasound imaging system and imaging method based on a three-dimensional tracking camera. The system includes: an ultrasound probe used for performing ultrasonic scanning on a region of interest of a target; a two-dimensional ultrasound imaging apparatus used for generating a two-dimensional ultrasound image of the region of interest on the basis of the ultrasound scanning; a three-dimensional spatial information acquisition apparatus, connected to the ultrasound probe and used for acquiring three-dimensional spatial information of the ultrasound probe; and a three-dimensional reconstruction module used for reconstructing a three-dimensional ultrasound image on the basis of the three-dimensional spatial information of the ultrasound probe and the two-dimensional ultrasound image. A three-dimensional ultrasound image can be reconstructed in a flexible, low-cost and small-dimension manner, and interference can be effectively avoided.

Abstract: An optical-based oscillometric blood pressure measurement device includes a cuff, which is pneumatically connected to an inflation/deflation unit and electronically connected to a pressure detection unit. It also includes light emission diode and photodiode pairs, and a volume detection unit that converts the plethysmogram received by the photodiode to the optical oscilloetrygram as the artery volume signal. Its control unit determines inflation/deflation slopes and the start/stop pressures and accurately traces the prescribed controller set point. Its extraction unit measures the systolic, diastolic, and mean arterial pressure accurately.

Abstract: A surgical system including a patient tracker and a tracking system. The patient tracker is adapted for attachment to a patient, and includes a hybrid marker having a radiological marker contained within an optical marker. The tracking system tracks the hybrid marker. A computing device obtains a three-dimensional image of a patient's anatomy and the attached patient tracker; identifies a three-dimensional portion of the hybrid marker within a scan volume; determines a location of the hybrid marker within the scan volume based on the identified three-dimensional portion; tracks the location of the hybrid marker in three-dimensional space using the tracking system while the patient tracker remains fixed to the patient; and registers the three-dimensional image in three-dimensional space based on a known geometric relationship between the location of the hybrid marker within the scan volume and the location of the hybrid marker in three-dimensional space.

Abstract: A method of generating corrected fluorescence data of concentrations of a targeted fluorophore in tissue of a subject includes administering first and second fluorescent contrast agents to the subject, the first contrast agent targeted to tissue of interest, the second agent untargeted. The tissue is illuminated with light of a first stimulus wavelength and first data is acquired at an appropriate emissions wavelength; the tissue is illuminated at a second stimulus wavelength and second data is acquired at a second emissions wavelength associated with the second agent, the first and second emissions wavelength differ. Difference data is generated by subtracting the second data from the first data. A system provides for stimulus and capture at multiple wavelengths, with image storage memory and subtraction code, to perform the method. Corrected data may form an fluorescence image, or is used to generate fluorescence tomographic images.

Abstract: Disclosed herein is an uroflowmeter which includes: a sensor having a signal transmitter transmitting an input signal to a detection area and a signal receiver receiving an echo signal reflected from urine passing through the detection area; a signal processing unit calculating uroflowmetry data based on a difference between the input signal and the echo signal, the uroflowmetry data being data about a flow of the urine passing through the detection area; and a diagnosis unit diagnosing urinary disorders of a test subject by comparing the uroflowmetry data calculated by the signal processing unit with preset reference uroflowmetry data.