Abstract: An analysis method and an electronic apparatus for breast image are provided. The method includes the following steps. One or more breast ultrasound images are obtained. The breast ultrasound images are used for forming a three-dimensional (3D) breast model. A volume of interest (VOI) in the breast ultrasound image is obtained by applying a detection model on the 3D breast model. The VOI is compared with a tissue segmentation result. The VOI is determined as a false positive according to a compared result between the VOI and the tissue segmentation result. The compared result includes that the VOI is located at a glandular tissue based on the tissue segmentation result. In response to the VOI being located in the glandular tissue of the tissue segmentation result, the VOI is compared with the lactiferous duct in the 3D breast model.

Abstract: A method of generating corrected fluorescence data of concentrations of a targeted fluorophore in tissue of a subject includes administering first and second fluorescent contrast agents to the subject, the first contrast agent targeted to tissue of interest, the second agent untargeted. The tissue is illuminated with light of a first stimulus wavelength and first data is acquired at an appropriate emissions wavelength; the tissue is illuminated at a second stimulus wavelength and second data is acquired at a second emissions wavelength associated with the second agent, the first and second emissions wavelength differ. Difference data is generated by subtracting the second data from the first data. A system provides for stimulus and capture at multiple wavelengths, with image storage memory and subtraction code, to perform the method. Corrected data may form an fluorescence image, or is used to generate fluorescence tomographic images.

Abstract: A method to automatically align magnetic resonance (MR) scans for diagnostic scan planning includes acquiring a three-dimensional (3D) localizer image of an anatomical object. One or more initial landmarks are identified in the 3D localizer image using a landmarking engine. One or more main axes associated with the anatomical object are identified based on the one or more initial landmarks. The 3D localizer image is registered to a canonical space based on the main axes associated to yield a registered 3D localizer image. The landmarking engine is applied to the registered 3D localizer image to yield one or more updated landmarks. A plurality of reference points for performing a MR scan are computed based on the one or more updated landmarks.

Abstract: A robot navigation system includes a handheld robot, a spatial information measuring device, a computing module and a display. The hand-held robot has a body, a tool and a movable connection mechanism. The movable connection mechanism is connected between the body and the tool, so that the tool can move relative to the body. The spatial information measuring device is configured to track the body, the tool and a target. The computing module is connected to the spatial information measuring device to obtain a plurality of relative positions between the body, the tool and the movable connection mechanism with respect to the target. The computing module calculates a guiding region according to the relative positions and mechanical parameters of the handheld robot. The display is configured to display the guiding region and the handheld robot based on the coordinate of the target.

Abstract: An intraluminal ultrasound imaging device includes a flexible elongate member configured to be positioned within a body lumen of a patient. The flexible elongate member includes a proximal portion and a distal portion. The device also includes an ultrasound imaging assembly disposed at the distal portion of the flexible elongate member. The ultrasound imaging assembly is configured to obtain imaging data of the body lumen. The ultrasound imaging assembly includes a transducer array including a substrate, a silicon oxide layer disposed over the substrate, and a plurality of rows of micromachined ultrasound transducer elements disposed on the silicon oxide layer. Two of the plurality of rows of micromachined ultrasound transducer elements are spaced apart by a trench formed by etching through a screen formed in the silicon oxide layer. Associated devices, systems, and methods are also provided.

Abstract: A system using images of a subject to assist in visualization of hidden portions of the subject is disclosed. The system may illustrate the images with a wearable display. The images may be displayed in an augmented or mixed reality manner.

Abstract: A micro impulse radar (MIR) system includes an MIR transceiver circuit configured to transmit, towards a subject, at least one transmitted radar signal, and receive at least one radar return signal. The system includes a control circuit configured to generate a control signal defining a radar signal parameter of the at least one transmitted radar signal, provide the control signal to the MIR transceiver circuit to cause the MIR transceiver circuit to transmit the at least one transmitted signal based on the radar signal parameter, and determine, based on the at least one radar return signal, a physiological parameter of the subject.

Abstract: A method of generating corrected fluorescence data of concentrations of a targeted fluorophore in tissue of a subject includes administering first and second fluorescent contrast agents to the subject, the first contrast agent targeted to tissue of interest, the second agent untargeted. The tissue is illuminated with light of a first stimulus wavelength and first data is acquired at an appropriate emissions wavelength; the tissue is illuminated at a second stimulus wavelength and second data is acquired at a second emissions wavelength associated with the second agent, the first and second emissions wavelength differ. Difference data is generated by subtracting the second data from the first data. A system provides for stimulus and capture at multiple wavelengths, with image storage memory and subtraction code, to perform the method. Corrected data may form an fluorescence image, or is used to generate fluorescence tomographic images.

Abstract: An MR Spectroscopy (MRS) system and approach is provided for measuring spectral information corresponding with propionic acid (PA), either alone or in combination with other measurements corresponding with other chemicals, to diagnose and/or monitor at least one of bacterial infection, such as associated with P. acnes, or conditions related thereto such as nociceptive pain associated with tissue acidity. An interfacing DDD-MRS signal processor receives output signals to produce a post-processed spectrum, with spectral regions corresponding with certain chemicals, including PA, then measured as biomarkers. A diagnostic processor derives a diagnostic value for each disc, and performs certain normalizations, based upon ratios of the spectral regions related to chemicals implicated in degenerative painful tissue pathology, such as PA and hypoxia markers of lactic acid (LA) and alanine (AL), and structural chemicals of proteoglycan (PG) and collagen or carbohydrate (CA).

Abstract: An image generation apparatus includes a plurality of electrodes, a plurality of sensor cells, and a controller configured to provide a tomographic image of a measurement object on the basis of an intensity of a magnetic field generated by an alternating current supplied via the plurality of electrodes. The controller acquires the intensity of the magnetic field via the plurality of sensor cells.

Abstract: Device 1 for fixation to the skull 2 of a patient that can serve as a fiducial marker in scan guided surgical operations using a surgical instrument. The device 1 comprises a material translucent for the applied electromagnetic waves of the scan and a fiducial marker and where the device 1 comprises means to fixate the device in a well-defined manner to the surgical instrument.

Abstract: Systems and methods for integrating a three-dimensional X-ray computed tomography system with an independent sound wave system to determine mechanical properties of tissue using signals from the sound wave system. Methods are disclosed that generate a numerical simulation and take the transmitted wave signals as the optimization objective to estimate modulus distribution of the tissue. Further, the mechanical properties of the tissue are reconstructed based on an inverse algorithm.

Abstract: A surgical clamp comprising two halves, each halve with an upper (2) and a lower portion (3), the lower portions forming two jaws (3) adapted to be in contact with a surgical site, one of the upper portions (2) being provided with a kinematic coupling mechanism (4, 5) and a passive circuit with a predetermined impedance value such that it is possible to identify different clamps because of their different impedances.

Abstract: The present application provides a personal hand-held monitor for the measurement of a subject's blood pressure and, optionally, one or more other vital signs, comprising a housing located on a personal hand-held computing device or a hand-held component of a computing system; a blood flow occlusion means located in the housing; a pressure sensor adapted to provide an electrical signal indicative of the pressure applied; a means for detecting the flow of blood in the body part of the subject when pressure is applied; and means for receiving electrical signals from the pressure sensor and the blood flow detecting means and for transmitting electrical signals indicative of the pressure and blood flow to the processor of the personal hand-held computing device or the computing system, wherein the processor of the personal hand-held computing device or computing system provide at least a measurement of the blood pressure of a subject.

Abstract: The disclosure provides a method and system for determining a lumen volume of a target blood vessel. The method may include acquiring a temporal sequence of angiography images of the target blood vessel after a contract agent is injected in the target blood vessel. The method may further include identifying a region of interest containing the target blood vessel, by a processor, in each angiography image in the temporal sequence of angiography images. The method may also include integrating, by the processor, pixel values in each region of interest, and determining the lumen volume, by the processor, based on the integrated values of the regions of interest and a predetermined correlation between the integrated values and volumes of the contrast agent.

Abstract: A device and method for fluorescent imaging may include an imaging unit including a fluorescent camera with an optical detector that is configured to acquire a fluorescent image of a fluorescing sample, the image including raw pixel values. A user interface may display an image formed from display image pixels derived from the raw image pixels. A distance sensor may measure a distance to the fluorescing sample. A distance between the optical detector and fluorescing sample may be determined from the measured distance. A processing unit may obtain a gain value, match the determined distance to a distance value associated a respective gain range, and impose limits of the gain values range onto the gain value, to determine a limited gain value. The limited gain value may be applied to the raw image pixels, thereby deriving display image pixels.

Abstract: A system comprises a catheter configured for delivery to a body cavity defined by surrounding tissue; a plurality of ultrasound transducers coupled to a distal end of the catheter; and an electronics module configured to selectively turn on/off each ultrasound transducer according to a predetermined activation sequence and to process signals received from each ultrasound transducer to produce at least a 2D display of the surrounding tissue. A user can selectively calculate and display various aspects of cardiac activity. The user can display Dipole Density (DDM), Charge Density (CDM), or Voltage (V-V). The shape and location of the chamber (surface), and the potentials recorded at electrodes can be displayed. The system can also change back and forth between the different display modes, and with post processing tools, can change how various types of information is displayed. Methods are also provided.

Abstract: The invention provides for a magnetic resonance antenna assembly (100) comprising one or more antenna elements (106), wherein the magnetic resonance antenna assembly further comprises multiple electronic dosimeters (108, 110, 204, 604) operable for measuring a cumulative radiation dose (470) of ionizing radiation (442) received by the magnetic resonance antenna assembly.

Abstract: A method includes receiving, from a probe that includes electrodes and is positioned inside a cavity in an organ of a patient, (i) proximity signals indicative of proximity of the electrodes to a wall of the cavity, and (ii) position signals indicative of positions of the electrodes within the cavity. Based on the proximity signals and the position signals, at least a portion of a volume of the cavity is represented by a sphere model including multiple spheres. A direction is identified along which one or more spheres are larger than one or more surrounding spheres by at least a given factor. Based on the indicated direction, a location of an opening in the wall of the cavity is estimated and presented to a user.

Abstract: Methods and systems are provided for ultrasound multiplexing. In one embodiment, a system comprises: an ultrasound probe comprising a transducer array and a multiplexer, wherein for a first signal and a second signal originating at the transducer array, the multiplexer multiplexes a sum signal and a difference signal formed from the first and the second signals into a multiplexed signal; and a console coupled to the ultrasound probe via a cable, the console including a processor, wherein the console receives the multiplexed signal via the cable, and wherein the processor generates an image from the first signal and the second signal recovered from the multiplexed signal. In this way, the number of processing channels can be reduced, thereby enabling a smaller ultrasound device with less hardware, while also avoiding signal degradation from channel crosstalk and transmission variation.