Abstract: Described is a Doppler-based non-invasive computational diagnostic method for personalized cardiology of subjects (e.g., patients with valvular diseases in both pre and post intervention status). The method may be performed for determining dynamic behavior of an aortic valve of the subject, the aortic valve having multiple asymmetric valve leaflets.

Abstract: A focused ultrasound treatment system has: a focused ultrasound unit configured to emit focused ultrasound waves to a focal region to perform treatment; an ultrasound imaging unit configured to, after treatment emit imaging ultrasonic waves to an imaging region and receive corresponding echoes, and image a corresponding vascular blood flow image on the basis of the echo; a region planning and parameter adjustment unit configured to re-delineate a focal region on the basis of the vascular blood flow image and to re-adjust a treatment parameter of the focused ultrasound unit so as to be used to next treat the re-delineated focal region. The imaging region contains the focal region.

Abstract: According to an embodiment, an ultrasonic diagnostic apparatus includes a control unit configured to analyze a shape of a Doppler waveform based on a Doppler signal, determine a type of the Doppler signal, determine at least one area of the Doppler waveform, calculate a similarity with respect to the at least one area, determine a measurement area based on the similarity, and calculate a measurement index based on the measurement area, and a display unit displaying the Doppler waveform, the measurement area, and the measurement index.

Abstract: An ultrasound probe 11 includes a housing 12, a transducer array 13 that is retained in the housing 12 and has a rear surface portion 13B, from which a wiring cable WC1 is drawn out, a circuit substrate 15 that is retained in the housing 12, the wiring cable WC1 being connected to the circuit substrate 15, a battery 14 that is retained in the housing 12 and performs power supply, and a fire protection structure that is disposed between the transducer array 13 and the circuit substrate 15 in the housing 12.

Abstract: Methods, systems, and computer-readable media for registering electromagnetic navigation data of a luminal network to a 3D model of the luminal network includes accessing a 3D model of a luminal network based on computed tomographic (CT) images of the luminal network, the 3D model corresponding to a CT coordinate space, selecting a plurality of reference points within the 3D model of the luminal network, accessing a plurality of survey points within the luminal network, the plurality of survey points being based on electromagnetic navigation data and corresponding to a body coordinate space, correlating the plurality of reference points and the plurality of survey points to determine pairs of correlated reference points and survey points; and deriving a transformation that maps the body coordinate space to the CT coordinate space based on the pairs of correlated reference points and survey points.

Abstract: Systems and methods for positioning and orienting an ultrasound probe include receiving a dataset derived from the ultrasound probe, wherein the dataset comprises at least one dataset obtained during a pulsed Doppler mode operation of the probe; analyzing the dataset to identify a current position and orientation of the probe relative to a target position and orientation, wherein the target position and orientation align the probe to correctly acquire a selected view of a body part; and conveying the current position and orientation of the probe relative to the target position and orientation.

Abstract: A medical image processing device according to an embodiment includes processing circuitry. The processing circuitry detects a contrast medium from a medical image. The processing circuitry sets a first region of interest and a second region of interest in the medical image. The processing circuitry calculates a density ratio between a density of the contrast medium included in the first region of interest and a density of the contrast medium included in the second region of interest.

Abstract: The invention generally relates to an adjustable headpiece with anatomical markers and methods of use thereof. In certain embodiments, the invention provides an apparatus that includes a headpiece configured to be worn on a head of a user. The headpiece includes at least a first receptacle configured to receive and retain a first energy source, and the headpiece is adjustable in at least one direction. There is at least one anatomical marker coupled to the headpiece. In that manner, a position of the receptacle can be adjustably aligned to a region of neural tissue in the head based on an alignment of the at least one anatomical marker with its designated anatomical structure.

Abstract: Apparatuses and methods for measuring total blood volume with ultrasound are disclosed. In one embodiment, a system for monitoring a blood volume of a patient includes an ultrasound transmitter configured for emitting an ultrasound toward a target blood vessel of the patient; and an ultrasound receiver configured for receiving the ultrasound reflected from the target blood vessel of the patient. The system also includes, a controller configured for: determining an expanded state of the blood vessel based on the ultrasound reflected from the target blood vessel; determining a collapsed stated of the blood vessel based on the ultrasound reflected from the target blood vessel; and determining the blood volume of the patient based on the ratio of the collapsed stated and the expanded stated of the blood vessel.

Abstract: A system and method by which a catheter tube may be automatically driven to a target location within the body of a subject, such as an enteral cavity or respiratory tract of the subject. The catheter tube may include an imaging device, a transceiver, a spectrometer, and a battery embedded in a tube wall at a distal end of the catheter tube. The imaging device may capture image data of structures proximal to the distal end of the catheter tube. An articulated stylet may be inserted in the catheter tube, which may be controlled by a robotic control engine according to navigation data generated by an artificial intelligence (AI) model based on the topographical image data. The spectrometer may sample and identify biomarkers proximal to the catheter tube. A remote computer may implement the robotic control engine and AI model and may wirelessly receive the image data from the transceiver.

Abstract: Ultrasound image devices, systems, and methods are provided. An ultrasound imaging system comprising a sequence generation component configured to generate a transmit pulse sequence comprising a first pulse sequence and a second pulse sequence time offset with respect to the first pulse sequence; a transmitter in communication with the sequence generation component and an ultrasound imaging component, the transmitter configured to transmit the transmit pulse sequence to the ultrasound imaging component to trigger, at the ultrasound imaging component, ultrasound wave emissions towards an anatomical object; a receiver configured to receive, from the ultrasound imaging component, ultrasound echo signals in response to the transmit pulse sequence; and a processing component in communication with the receiver and configured to generate at least one of structural data or motion data associated with the anatomical object based on the received ultrasound echo signals.

Abstract: An ultrasound diagnostic apparatus includes an ultrasound probe, an image generation unit that generates an ultrasound image on which a breast of a subject is captured by performing transmission and reception of an ultrasound beam by using the ultrasound probe for the subject, a schema image generation unit that generates a schema image on which a region of interest is plotted based on a synthesized two-dimensional image generated by using a series of radiation images obtained by tomosynthesis imaging and on which the breast of the subject is captured, information on a tomosynthesis image accompanying the synthesized two-dimensional image and corresponding to the region of interest on the synthesized two-dimensional image, and information on the region of interest, and a monitor that displays the ultrasound image, the synthesized two-dimensional image, and the schema image.

Abstract: Techniques for determining fetal situs during an ultrasound imaging procedure are disclosed. The techniques can include obtaining an ultrasound image of a fetus in utero. The fetus will include a torso and a spine and the ultrasound image can comprise a circumferential view of the torso of the fetus. The circumferential view can include at least: (i) an outer border of the torso, and (ii) the spine that includes three landmarks arranged in a triangular orientation. The techniques can further include superimposing a fetal overlay based on an alignment instruction corresponding to an alignment between the outer border of the torso and the three landmarks to obtain an augmented reality image of the fetus. The fetal overlay can include a graphical element indicating a left side and a right side of the fetus. The augmented reality image of the fetus can be output on a display of the ultrasound machine.

Abstract: An ultrasound diagnostic apparatus includes: an ultrasound probe; an image acquisition unit that continuously acquires an ultrasound image of a blood vessel using the ultrasound probe; a blood vessel detection unit that detects the blood vessel from the ultrasound image; a blood vessel information acquisition unit that acquires blood vessel information of the blood vessel detected by the blood vessel detection unit; a needle information acquisition unit that acquires needle information of a puncture needle; an estimated reaching position calculation unit that calculates an estimated reaching position of the puncture needle based on a designated insertion position of the puncture needle, the blood vessel information, the needle information, and a predetermined needle insertion angle range; a monitor; and a display controller that displays the estimated reaching position calculated by the estimated reaching position calculation unit on the monitor.

Abstract: A method for using metastable perfluorocarbon nanodroplets for ultrasonic lysis of blood clots includes administering metastable perfluorocarbon nanodroplets into a blood vessel that includes or that leads to a blood vessel that includes a blood clot, the metastable perfluorocarbon nanodroplets each have a liquid core comprising a perfluorocarbon material that has a boiling point below 25° C. at atmospheric pressure and that remains stable in liquid form at 25° C. at atmospheric pressure. The method further includes applying ultrasound energy to the perfluorocarbon nanodroplets within or surrounding the blood clot, causing the perfluorocarbon nanodroplets to vaporize and convert to bubbles, which cavitate and lyse the blood clot.

Abstract: A portable device for detecting a large vessel occlusion in a patient's brain by transmitting a signal into both sides of the brain and receiving the reflections of the transmitted signals to capture a single reflection data point of the characteristics of the blood vessels and brain tissue on both sides of the brain. Using the captured single reflection data point values to perform a comparative analysis between the right and left side of the brain, and based on this analysis, assessing whether the patient is experiencing a large vessel occlusion. If so, the device generates an alert.

Abstract: In exemplary examples, methods and systems for treating vascular disease by implanting a stent within the vasculature and using intravascular imaging to determine and ensure that the stent was property implanted and producing a desirable and effective results is disclosed herein. For example, a system may obtain optical shape sensing data and intravascular imaging data for a blood vessel. The system may process the optical shape sensing data and the intravascular imaging data to generate a three-dimensional model and image of the blood vessel immediately before and immediately after stent implantation into the blood vessel, and perform a precise comparison of the before and after images to ensure that the stent was properly implanted and will produce or is producing a desirable and effective result. The precise comparison may be based on a derived diameter associated with the location at which the stent is placed in the blood vessel based on the generated pre and post generated three-dimensional models.

Abstract: Ultrasound image devices, systems, and methods are provided. An ultrasound imaging system, comprising an intraluminal imaging device including an ultrasound transducer array configured to obtain first signal data and second signal data representative of a body lumen, the first signal data and the second signal data associating with different imaging modes of the ultrasound transducer array; and a processor in communication with the intraluminal imaging device and configured to generate motion data of a flow within the body lumen based on the first signal data; generate structural data of the body lumen based on the second signal data; combine the motion data and the structural data based on a first threshold; and output, to a display in communication with the processor, an intraluminal ultrasound image representing the combined motion data and structural data.

Abstract: The disclosure provides methods for diagnosis or prediction of the likelihood of a subject experiencing obstructive sleep apnea, determined at least in part by measuring the degree of tongue fat in a subject using, e.g., thermal imaging, THz imaging or other multispectral imaging.

Abstract: Embodiments disclosed herein are directed to a vessel assessment system configured to image a target vessel and determine which vascular access device (VAD) to use to access the target vessel while remaining within one or more insertion parameters of percentage vessel occupancy, and dwell length given a predetermined range of insertion angles. The system can superimpose a target vessel sizing ring to measure a diameter or cross-sectional area, or to measure a depth of the target vessel. Further, the system can provide a list of VAD's that can access the target vessel within one or more insertion parameters. The system can provide an icon representing the VAD superimposed over the target vessel to provide a visual representation of the vascular access device within the target vessel.