Abstract: A microcontroller coupled to sensors integrated into a physical toy for monitoring free play activity of a human subject wherein patterns in play activity sensed by the microcontroller are graphically visualized for identification of behavioral milestones, developmental progress and/or behavioral disorders. Specifically, accelerometers detect movement of toys which determine: (1) if the toy is being played with; and (2) the intensity in which the toy is moved. Pressure sensors detect the level and location in which a child may hold a toy. Synchronized with an audiovisual record of the play therapy session and a computer-generated avatar representation of the physical object, this data is integrated to find peak levels of behavior giving clinicians more efficient analytical tools.

Abstract: A mouth guard senses concussive forces, calculates risk factors for head injury, and displays status of risk and potential injury. The mouth guard may be used to identify, treat and prevent exacerbating injury. The mouth guard can be programmed with biometric data to better calculate and anticipate impact thresholds and more precisely predict and prevent injury.

Abstract: A closure for protectively scaling a biological fluid collection device is disclosed. The closure includes a cap and an adapter or connector. The closure of the present disclosure allows for connection to multiple different blood collection devices. In a first configuration, with the cap connected to the adapter, the closure may be connected to a first blood collection device. In a second configuration, with the cap disconnected from the adapter, the closure may be connected to a second blood collection device. An advantage of the closure of the present disclosure is that it enables a single closure device to accommodate a variety of connection options, hi one embodiment, the closure includes a barrier in communication with a portion of the cap, and the barrier protectively shields a portion of the stopper and/or protectively shields a portion of the cap.

Abstract: An apparatus for measuring impedance is provided. The apparatus may include an electrode part in which a plurality of electrodes are arranged; a depth controller configured to configure electrode clusters from among the plurality of electrodes of the electrode part based on a measurement depth of the object, and generate a control signal; a switch configured to connect electrodes in the electrode clusters to signal lines based on the control signal; and a measurer configured to measure the impedance of the object based on signals measured through the electrode clusters.

Abstract: A respiratory gas flow coupling includes a device connector having a female receptacle or male nipple with a side-oriented leak path. A patient accessory connector has a male nipple or female receptacle adapted to connect with the female receptacle or male nipple of the device connector. The patient accessory connector seals the side-oriented leak path of the female receptacle or male nipple of the device connector when the patient accessory connector is connected with the device connector. The side-oriented leak path is disposed at a position such that a shorter male nipple or female receptacle of an incompatible patient accessory connector which is shorter than the male nipple of the patient accessory connector does not seal the side-oriented leak path when the incompatible patient accessory connector with the shorter male nipple is connected with the device connector.

Abstract: A pulse diagnosis apparatus includes a base, a bearing and a plurality of sensing module. The base has a motion module. The motion module is disposed on the base and moves back and forward in a first direction. The bearing is disposed on the motion module and includes a first face and a second face. Each sensing module includes a driving element, a flexible element and a sensing unit. The driving element moves in the first direction and passes through the bearing. The driving element includes a first terminal and a second terminal. The first terminal is adjacent to the second face. The second terminal is adjacent to the first face. The flexible element is hitched up the driving element. Two terminals of the flexible element are against the second terminal and the bearing. The sensing unit is disposed on the second terminal.

Abstract: Devices, methods and systems related to the assessment and therapy of neurological conditions and dexterous hand function in particular. For example, some embodiments can relate to devices comprising a first portion of flexible material and forming a cavity; a second portion non-flexible material; a PCB coupled to the second portion; and wherein a portion of an edge of the first portion is configured to create a semi-hermetic seal with at least a portion of an edge of the second portion and the PCB has connected thereto a pressure sensor, a wireless transceiver, and a power storage unit.

Abstract: A system of sensors integrated into toys for monitoring free play activity of a human subject wherein patterns in play activity automatically are weighted into a pattern for identification of behavioral milestones, developmental progress and/or behavioral disorders. Specifically, accelerometers detect movement of toys which determine: (1) if the toy is being played with; and (2) the intensity in which the toy is moved. Pressure sensors detect the level and location in which a child may hold a toy. Synchronized with an audiovisual record of the play therapy session and a computer-generated avatar representation of the physical object, this data is integrated to find peak levels of behavior giving clinicians more efficient analytical tools.

Abstract: Cognitive function evaluation device includes: storing unit storing reference data on the relationship between the periodicity of a body movement of a person walking and the cognitive function level of the person; acquiring unit that acquires body movement data on the detected body movement from body movement sensor that detects the body movement of subject walking; and calculating unit that calculates the periodicity of the body movement while walking from the acquired body movement data and checks the calculated periodicity against reference data stored in storing unit so as to identify the cognitive function level corresponding to the calculated periodicity.

Abstract: A method for determining a muscle fatigue of a muscle includes a first step of electrostimulating the muscle at different frequencies. A second step of the method includes determining forces developed by the muscle in response to the electrostimulations of the first step. A third step includes determining a muscle fatigue on basis of the forces determined in the second step.

Abstract: Embodiments of the present disclosure provide respiration monitoring systems and methods for using same. The respiration monitoring device can include a first accelerometer, a second accelerometer, at least one acoustic sensor, a memory comprising a lookup table, a real-time clock, and one or more instructions, and a processor for receiving one or more motion signals from each accelerometer and one or more sound signals from each acoustic sensor. The processor can correlate the one or more motion signals to a distance value, correlate the one or more sound signals to a sound value, filter the distance value and the sound value according to limitations stored in the lookup table, assign a time stamp to each filtered value, determine local maximums for the filtered motion values and local minimums for the filtered sound values, and match the local maximums to the local minimums to confirm a completed breath.

Abstract: A method and system for monitoring the effectiveness of a patient's diabetes treatment plan by predicting, on a frequent basis, the patient's glycated hemoglobin (A1c) based on the patient's blood glucose (BG) may include applying a plurality of A1c models to a BG data set of the patient so as to obtain a plurality of calculated A1c values and identifying a best fit model amongst the plurality of A1c models by evaluating the plurality of calculated A1c values against at least one measured A1c value; calculating a predicted A1c value by applying the identified best fit model to the BG data set. Some embodiments may further include evaluating the predicted A1c value against a set of escalation rules to determine whether an escalation alert is required; alerting the patient's healthcare provider when it is determined the escalation alert is required; and outputting the predicted A1c value to the patient.

Abstract: An example method includes, determining, based on data received from a plurality of sensors that are each attached to a respective finger of a plurality of fingers of a hand of a patient, data that represents movements of one or more fingers of the plurality of fingers; and determining, based on the data that represents the movements of the one or more fingers, one or more objective indications of motor control of the patient.

Abstract: A non-invasive system and method for measuring blood pressure variability includes a cuff (20) pneumatically connected to a pump (14) to inflate the cuff to be wrapped around a limb (21) of a subject. A pressure sensor (18) is associated with the cuff for measuring cuff pressure (52). A photoplethysmogram sensor (26) attached to a fingertip in the same limb (21) of the subject and placed distal to the cuff for monitoring blood flow and recording a pulse plethysmograph signal. A control unit (12) connected to the pressure sensor (18) and the photoplethysmogram sensor (26) for simultaneously recording the cuff pressure and the plethysmograph signal such that an empirical relationship is derived between the cuff pressure and an amplitude measure of the plethysmograph signal (54) to measure short-term variation in systolic and diastolic blood pressures at a frequency corresponding to respiratory cycle.

Abstract: Adaptive respiratory condition assessment can include capturing signals generated by sensors of a portable device positioned to sense a user's body. The sensors can generate the signals in response to sensor-detected movements of the user's body measured along multiple axes and corresponding to lung activity in the user's body during respiratory cycles. A preferred axis of measurement can be selected using signal processing performed by a signal processor embedded in the portable device. Waveforms generated from signals corresponding to signals generated in response to movements of the user's body measured along the preferred axis can be filtered for extracting biomarkers from the waveforms using the signal processor. The one or more biomarkers extracted correspond to the lung activity. Based on the biomarkers, a respiratory condition of the user can be determined. A notification based on the respiratory condition as determined can be generated and conveyed with the portable device.

Abstract: Existing wearable device-based approaches to capture a_tremor signal have accuracy limitations due to usage of accelerometer sensor with inherent noisy nature. The method and system disclosed herein taps characteristics of the PPG sensor of being sensitive to the motion artifact, as an advantage, to capture tremor_signals present in the PPG sensor. The method disclosed herein describes an approach to extract tremor_signals of interest from the PPG signal by performing a Singular Spectrum Analysis (SSA) followed by spectrum density estimation. The SSA comprises performing embedding on the acquired PPG signal, performing Principal Component Analysis (PCA) on the embedded signal and reconstructing the rest tremor signal from the significant principal components identified post the PCA. Further, the spectrum density estimation detects a dominant frequency present in the principal components, which is the dominant frequency associated with the rest tremor.

Abstract: An electronic system for bioimpedance signal acquisition, comprises: a current signal injection module configured for generating a current signal to be applied to a subject; a bioimpedance signal measurement module configured for measuring a bioimpedance signal based on a voltage generated by the current signal; a data quality detection module configured for detecting an AC or a DC level of the measured bioimpedance signal and detecting whether the AC or DC level is within or outside an AC reference value range and a DC reference value range, respectively; and a signal adaptation module configured for modifying at least one parameter of the current signal injection module or the bioimpedance signal measurement module based on said detection of the AC or DC level in relation to the AC reference value range and the DC reference value range, respectively.

Abstract: A blood pressure measurement module includes a base, a valve plate, a top cover, a micro pump, a driving circuit board, and a pressure sensor. The valve plate is disposed between the base and the top cover. The micro pump is in the base. The pressure sensor is disposed on the driving circuit board. An inlet channel of the top cover and the pressure sensor are connected to a gas bag. The micro pump operates to inflate the gas bag to press the skin of a user. The pressure sensor detects a pressure change in the gas bag so as to detect the blood pressure of the user.

Abstract: A syringe-based device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive and isolate a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.

Abstract: A blood pressure measuring device includes a device main body; a curler configured to bend along a circumferential direction of a wrist of a living body, including one end and another end separated from each other, also configured to come into contact with a portion of the wrist at least between a dorsal side and a palmar side; a strap provided to the device main body; a sensing cuff arranged in a region of the wrist where arteries exist; a back plate provided between the curler and the sensing cuff and extending in a circumferential direction of the wrist; a pressing cuff provided on a side of the curler nearer to the strap and configured to press the sensing cuff; and a cuff provided on a side of the curler nearer to the living body and arranged on the dorsal side of the wrist.