Patents Examined by Jonathan M Foreman
  • Patent number: 10194813
    Abstract: Systems, devices and methods that can be used to obtain objective pressure measurements in a body cavity using one or more monitoring bladders mounted on a catheter. The monitoring bladders may be adapted to connect or be connected to a system capable of providing objective pressure measurements indicative of the compressive forces acting on the one or more monitoring bladder in the body cavity. The body cavity may include, for example, the rectum, esophagus, stomach, intestine, colon, reproductive tract, urethra, oronasopharnygeal tract, etc.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: February 5, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Adil E. Bharucha, Randolph W. Stroetz
  • Patent number: 10179225
    Abstract: A guidewire introducable into a bodily lumen having an obstruction therein is provided. An introducer needle is advanced through tissue and into the bodily lumen. A guidewire is advanced through the introducer and into the lumen. The guidewire is advanced further through the lumen until an atraumatic distal tip of the guidewire encounters an obstruction the distal tip cannot pass in a straight forward manner. The distal tip is pressed against the obstruction such that a flexible segment proximal of the distal tip forms a loop distal of the distal tip. The guidewire is advanced further through the lumen such that the loop of the flexible segment is pushed past the obstruction and the distal tip is pulled distally past the obstruction. A greater diameter guidewire extension can be coupled to the back end of the guidewire, providing function as a larger diameter guidewire.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: January 15, 2019
    Inventors: Thomas A. Sos, Mitchell Tatum
  • Patent number: 10149651
    Abstract: Systems and methods are disclosed for obtaining rheological properties of viscoelastic medium, and in particular, in-vivo evaluation of body fluid such as the vitreous. The system includes a needle-like probe having a distal and a proximal end, a rotational actuator, and a sensor coupled to the rotational actuator. The proximal end of the probe is configured for attachment to the rotational actuator. The distal proximal end of the probe has a roughened outer circumferential surface extending axially along at least a portion of the distal end, wherein the roughed distal end of the probe is configured to be disposed within the viscoelastic medium, and wherein the sensor is configured to obtain measurements corresponding rotation of the probe within the viscoelastic medium.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: December 11, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Hossein Pirouz Kavehpour, Pooria Sharif-Kashani, Jean-Pierre Hubschman
  • Patent number: 10143416
    Abstract: A method for characterization of a patient's esophagus may include receiving data measured by an impedance and high resolution manometry catheter in an esophagus in which the data may be representative of a pressure and/or an impedance associated with a swallowing event. The method may also include determining a cross-sectional area of the esophagus based on the received data and a pre-determined amount of a bolus consumed during the swallowing event. Systems and apparatus for characterizing a patient's esophagus may also include measuring data with a high resolution manometry catheter to determine the cross-sectional area, work, and compliance of the esophagus as a function of time during a swallowing event. Averaged data may establish a database of normal values for work done and compliance and allow for comparison of a patient to normal pathology.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: December 4, 2018
    Assignee: The Regents of the University of California
    Inventor: Valmik Bhargava
  • Patent number: 10111604
    Abstract: An apparatus for detecting abnormal masses such as breast cancer includes a measurement sensor configured to obtain a voltage at a first area of a first breast of a subject; a reference sensor configured to obtain a voltage at a second area of a second breast of the subject, a position of the first area corresponding to a position of the second area; and a detector, wherein the detector includes a differential amplifier configured to amplify a voltage input from the at least one of the measurement sensor and the reference sensor; an active low pass filter configured to pass a signal frequency of a low frequency band among signals transmitted from the differential amplifier; a driver amplifier configured to amplify a signal passed through the active low pass filter; and an analog-to-digital (AD) converter configured to convert the signal amplified by the driver amplifier into a digital signal.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: October 30, 2018
    Inventor: Kyongho Lee
  • Patent number: 10092277
    Abstract: An aspiration apparatus includes a barrel having a needle receiving end and a piston receiving end. The barrel has an inner diameter and an outer diameter. The piston receiving end of the barrel has substantially the same inner diameter as the inner diameter of the barrel. The barrel has an opening therein through a sidewall of the barrel. The opening is between the needle receiving end and the piston receiving end. The opening is distant from the needle receiving end. The aspiration apparatus also includes a needle sealingly attached to the needle receiving end of the barrel, and a piston having an end which substantially seals to the inner diameter of the barrel. The piston is capable of a number of positions including a first position near the needle receiving end, a third position past the opening in the barrel.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: October 9, 2018
    Assignee: GREER MEDICAL, INC.
    Inventors: Zine-Eddine Boutaghou, Peter Crane
  • Patent number: 10045760
    Abstract: The present invention provides a device that can move inside a biological conduit such as an intestinal tract for sampling the content therein, and a process thereof. While moving along the intestinal tract, the device can continuously collect the content in the intestinal tract. One or more convoy belts having an adsorbent layer are configured to continuously absorb and preserve the collected intestinal content. The belt loaded with the sample may be used to establish a chemical, biochemical and microbiological spectrum along the length of the intestinal tract.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: August 14, 2018
    Inventors: Xibo Wei, Sara Shi Wei
  • Patent number: 9999407
    Abstract: Provided herein are a device and methods to obtain multiple serial samples from biologic tissues located in a tubular or cavitary space of a body. The device has a proximal and distal end, with a linear shaft connecting both ends. The distal end of the device comprises a tissue cutting assembly, a sample transport assembly and a sample storage assembly. The sample transport assembly comprises a slidable sample transport unit, a semi-cylindrical tubular sample chamber with a pair of axially linear rails located on both sides of said chamber and a system of differential pull wires. The sample transport unit slides on the rails of the sample chamber, providing longitudinally axial movement of the cup connected to said sample transport unit. The sample storage assembly comprises said sample chamber, a reversibly detachable sample catcher inserted in said sample chamber, a tubular sample housing and an expandable tubular sample housing.
    Type: Grant
    Filed: January 21, 2012
    Date of Patent: June 19, 2018
    Inventor: Choon Kee Lee
  • Patent number: 9993617
    Abstract: An elongated surgical manipulator apparatus and method of operating enables determination of the shape of a flexible portion of the elongated surgical manipulator and/or the location of an arbitrary point thereon, as well as a measure of a contact force exerted on a distal portion of the manipulator. A plurality of fiber optics are operatively coupled with the manipulator, each of the fiber optics including a plurality of fiber Bragg gratings for determination of the shape and/or position. Each of the fiber optics further includes a fiber optic strain gauge such as a Bragg grating or a Fabry-Perot resonator at a distal portion of the elongated surgical manipulator that is isolated from the strain associated with the bending of the manipulator. The fiber optic strain gauges at the distal portion may thus be used to detect a force vector (magnitude and direction) imposed on the distal portion.
    Type: Grant
    Filed: January 6, 2014
    Date of Patent: June 12, 2018
    Assignee: St. Jude Medical International Holdings S.À R.L.
    Inventor: Giovanni Leo
  • Patent number: 9987469
    Abstract: A guidewire introducable into a bodily lumen having an obstruction therein is provided. An introducer needle is advanced through tissue and into the bodily lumen. A guidewire is advanced through the introducer and into the lumen. The guidewire is advanced further through the lumen until an atraumatic distal tip of the guidewire encounters an obstruction the distal tip cannot pass in a straight forward manner. The distal tip is pressed against the obstruction such that a flexible segment proximal of the distal tip forms a loop distal of the distal tip. The guidewire is advanced further through the lumen such that the loop of the flexible segment is pushed past the obstruction and the distal tip is pulled distally past the obstruction. A greater diameter guidewire extension can be coupled to the back end of the guidewire, providing function as a larger diameter guidewire.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: June 5, 2018
    Inventor: Thomas A. Sos
  • Patent number: 9974930
    Abstract: A guidewire (1) for re-canalizing a vascular occlusion comprises a core wire (5) which terminates at its distal end (4) in a terminal member (7) for opening the occlusion. A helical coil sleeve (10) extends around the core wire (5) from the terminal member (7) to a location (11) along the core wire (5). The terminal member (7) defines first and second planar surface portions (13, 14), which converge towards a distal transversely extending leading edge portion (8). In use, as the terminal member (7) is urged through the vascular occlusion, the first and second surface portions (13, 14) act on the occlusion to form an opening therethrough. A distal portion (28) of the core wire (5) is of spade-like configuration for facilitating bending thereof for directing the terminal member (7) out of a central major plane (35) defined by the distal portion (28) for facilitating aligning of the terminal member (7) with a branched vessel of the vascular system.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: May 22, 2018
    Assignee: Brivant Research & Development Limited
    Inventors: Henry William Lupton, Mark Bruzzi
  • Patent number: 9949662
    Abstract: Aspects of the present disclosure are directed to a CPU and a memory circuit that has user-corresponding data stored on the memory circuit, and a platform over which a plurality of electrodes are interleaved, and configured for engaging the user. While the plurality of electrodes is concurrently contacting a limb or other extremity of the user, measurement signals are obtained from the plurality of electrodes. Based on a plurality of impedance-measurement signals being obtained from the electrodes, signals are generated that correspond to cardiovascular timings of the user. In such aspects of the present disclosure, pulse characteristic signals are determined based on the plurality of impedance-measurement signals. One of the pulse characteristic signals is extracted, and used as a timing reference to extract and process another pulse characteristic signal.
    Type: Grant
    Filed: July 18, 2014
    Date of Patent: April 24, 2018
    Assignee: Physiowave, Inc.
    Inventors: Laurent B. Giovangrandi, Gregory T. Kovacs, Robert Bruce Darling
  • Patent number: 9943241
    Abstract: Aspects of the present disclosure are directed toward obtaining a plurality of impedance-measurement signals while a set of at least three electrodes are concurrently contacting a user. Additionally, various aspects of the present disclosure include determining a plurality of pulse characteristic signals based on the plurality of impedance-measurement signals. One of the pulse characteristic signals is extracted from one of the impedance-measurement signals and is used as a timing reference to extract and process another of the pulse characteristic signals.
    Type: Grant
    Filed: July 15, 2014
    Date of Patent: April 17, 2018
    Assignee: Physiowave, Inc.
    Inventors: Laurent B. Giovangrandi, Gregory T. Kovacs, Robert Bruce Darling
  • Patent number: 9925068
    Abstract: A bone harvester and bone marrow removal system. The bone harvester can include a body defining a channel extending longitudinally therethrough from a distal to a proximal portion of the body. The distal portion can include a cutting tip. Bone marrow may be drawn through the channel.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: March 27, 2018
    Assignee: Treace Medical Concepts, Inc.
    Inventors: F. Barry Bays, David L. Brumfield, Joe William Ferguson, Carlos Eduardo Gil
  • Patent number: 9907488
    Abstract: A high intensity preparation, physical exercise and recovery system configured to prepare muscles for workout through vibration, accept muscular input of high intensity, recover muscles through vibration. Embodiments provide an exercise system that enables a user to obtain a high intensity workout in a small amount of time, for example 15 minutes, and yet increase the user's metabolic rate for hours. Embodiments of the invention may further perform an initial and/or ongoing analysis in terms of body composition analysis and/or extremity composition analysis/score in order to target particular muscles, fat and/or skeletal areas. In one or more embodiments the system may provide outputs including suggested alterations in physical activity and/or food to consume in order to achieve targeted goals for example as compared to the user's trends of change over time, or in comparison to other user's trends down to the granularity of extremities and not just overall body metrics.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: March 6, 2018
    Assignee: GHB, LLC
    Inventors: Gene Barduson, Ted Barduson
  • Patent number: 9901403
    Abstract: A medical device such as an oximeter includes a marking feature. In an implementation, a marking mechanism of the device marks tissue based on a location of where a measurement was taken by the device. In an implementation, the marking mechanism of the device marks tissue based on an oxygen saturation measurement obtained by the device.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: February 27, 2018
    Assignee: ViOptix, Inc.
    Inventors: Larry C. Heaton, II, Robert E. Lash
  • Patent number: 9895104
    Abstract: The device performs reference point indentation without a reference probe. The indentation distance is measured relative to the instrument which remains substantially stationary during the impact process, which occurs on the order of one millisecond. In one embodiment, an impact motion with a peak force of order 28N creates an indentation in bone with a depth of approximately 150 ?m during which the instrument case moves less than 1 ?m. Thus the error in measuring indentation depth due to the motion of the case is less than 1%, making a reference probe unnecessary. Further, this “error” is consistent and can be corrected. In one embodiment, the device measures the fracture resistance of hard tissues by actually creating microscopic fractures in the hard tissues in a measured way. It creates these microscopic fractures by impacting the sample with a sharpened probe. The indentation distance in the sample is correlated with fracture resistance.
    Type: Grant
    Filed: July 12, 2011
    Date of Patent: February 20, 2018
    Assignee: The Regents of the University of California
    Inventors: Randall Connor, Daniel Bridges, Paul Hansma
  • Patent number: 9895068
    Abstract: The present disclosure provides a system and method for determination and indication of the time remaining before a patient's physical characteristics are displayed on a monitor. The indication may be a numeric count-down, a progress bar, a clock face, an audible signal, or any other time and/or progress indication. The approximate wait-time may be determined, for example, by adding the known, generally fixed durations of characteristic determination processes to the calculated, variable durations of characteristic determination processes. Exemplary processes which may have generally fixed durations include monitor boot-up, sensor validation, and sensor calibration. Exemplary processes which may have variable durations include sensor location determination and pulsation detection. The sum of the pre-determined and calculated durations may be an approximate wait-time, which is indicated to a caregiver via visual or audible display.
    Type: Grant
    Filed: June 30, 2008
    Date of Patent: February 20, 2018
    Assignee: Covidien LP
    Inventors: Clark R. Baker, Daryl Bordon
  • Patent number: 9888861
    Abstract: Various embodiments concern identifying a biomarker in the presence of electrical stimulation. Various embodiments concern delivering electrical stimulation to a patient and sensing one or more signals while the electrical stimulation is being delivered, the one or more signals including data indicative of physiological activity. Various embodiments further include determining an intensity of the electrical stimulation and determining whether the data indicates the presence of a biomarker based on a variable threshold, the variable threshold being variable based on the intensity of the electrical stimulation. Various embodiments concern determining a relationship between stimulation intensity and a biomarker parameter to determine the variability of the variable threshold.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: February 13, 2018
    Assignee: Medtronic, Inc.
    Inventors: David L. Carlson, Pedram Afshar, Timothy J. Denison, Jonathon E. Giftakis, David E. Linde, Scott R. Stanslaski
  • Patent number: 9888869
    Abstract: An apparatus for neural block determination is provided including processing circuitry configured to receive muscle movement measurements, analyze the muscle movement measurements in a frequency domain, and determine an effectiveness of an anesthetic based on the analysis of the muscle movement measurements in the frequency domain.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: February 13, 2018
    Assignee: The Johns Hopkins University
    Inventors: Wayne I. Sternberger, Robert S. Greenberg