Abstract: A knee joint prosthesis including a femoral component for attachment to a femur. The femoral component includes an anterior portion, first and second condylar portions extending from the anterior portion and having first and second bearing surfaces, the first and second condylar portions having first and second posterior ends, and a third condylar portion defined between the first and second condylar portions and extending anteriorly beyond the first and second posterior ends.

Abstract: A prosthetic mitral heart valve having four separate flexible leaflets. The heart valve includes a support frame that may be non-circular, for example elliptical or “D-shaped”. The support frame may have an undulating outflow edge defined by four inflow cusps and four outflow commissures to which each of the flexible leaflets attaches. The support frame may comprise an undulating wireform and a surrounding stent defining a structure having four cantilevered posts projecting in the outflow direction to support the four leaflets. The heart valve is designed to be secured in the annulus and function as a standalone unit without papillary muscle connections to the leaflets. The four leaflets may be arranged in two opposed pairs, one pair being smaller than the other pair. The larger pair of leaflets may be identical, or differently sized. Existing sizes of heart valve leaflets may be utilized with the smaller leaflets being at least two leaflet sizes smaller than the larger leaflets in odd millimeter increments.

Abstract: Embodiments of the invention provide for a unidirectional flow valve. For example, embodiments of the invention include a method of providing a unidirectional flow valve to a vein that include folding a first portion of a vein over an adjacent second portion of a vein and engaging at least two opposing areas of the second portion of the vein to adjacent areas of the first portion of the vein. The at least two opposing walls of the second portion of the vein define the unidirectional flow valve. At least one support device may be inserted into the folded valve region of the vein to maintain the folded configuration of the valve.

Abstract: The present invention provides a bioactive, small-diameter (typically less than 6 mm in internal diameter) vascular graft prosthesis, and is a textile conduit preferably manufactured using a novel electrospinning perfusion methodology. One preferred embodiment is a nanofibrous biocomposite textile conduit which comprises a prepared liquid admixture of polyester (Dacron), a biodurable implantable synthetic polymer, and Type IV collagen, an extracellular matrix protein. This prepared admixture and blending of diverse fibrous matter is utilized in a novel electrospinning perfusion process to form a small-diameter (less than 6 mm) fabricated textile conduit, a discrete article of manufacture, which then serves as an antecedent tangible workpiece for a subsequently-made prosthetic vascular graft construct.

Abstract: An improvement in a total stabilized knee prosthesis wherein stabilization against uncontrolled relative rotation between a femoral component and a tibial component about a longitudinal axis, during articulation of the knee prosthesis, is attained by the engagement of a femoral stabilizing compartment with a tibial stabilizing post, the improvement including profile contour configurations on inner surface portions of condylar surfaces and on corresponding outer surface portions of tibial articular surfaces, the profile contour configurations being flared outwardly, in directions away from an intermediate sagittal plane, along posterior aspects of the condylar surfaces and the tibial articular surfaces engaged through deep flexion for providing an engagement between the profile contour configurations sufficient to establish a desired level of constraint against relative rotational movement between the femoral component and the tibial component about the longitudinal axis enabling a decrease in the level of con

Abstract: A femoral stem for hip prosthesis is disclosed comprising: a main body with a mainly longitudinal development and a generally wedge shaped, which is inserted into the femoral canal present in the body of the femur; a central body of a generally trapezoidal shape integral with the main body, located in the proximal zone of the femur; an appendix projecting from the central body provided with a terminal pin receiving spherical head of joint into the cotyle belonging to the prosthesis and inserted into the acetubular zone of the pelvic bone. The main body and the central body are defined by a shaped surface on one side and a mixtilinear surface on the opposite side from which a shaped notch is starting involving the central body and extending up to the proximity of the projecting appendix.

Abstract: An implantable prosthetic valve that is transformable from a first helical pre-implantation configuration to a second valvular functional configuration, and methods of delivery.

Abstract: An expandable stent comprised of a plurality of helical segments is disclosed. In one embodiment, the stent is generally cylindrical in shape having a cylindrical axis, and comprises a first and second set of helical segments. The helical segments in the first set are substantially parallel and have a first pitch forming a first helical angle with respect to the cylindrical axis. The helical segments in the second set are also generally parallel to each other and form a second pitch that differs from the first pitch, thereby forming a second helical angle with respect to the cylindrical axis. In an alternative embodiment, the stent comprises one set of helical segments and a plurality of circumferential elements that are joined together by the helical segments to form a plurality of cylindrical elements which are joined together to form a stent body. The stent may also have endzones.