Abstract: An esophageal monitoring device includes a camera and, optionally, one or more lights to enable visualization of an interior of a subject's esophagus. Visualization of the interior of the subject's esophagus before and after a left atrial ablation procedure may enable a healthcare provider to determine whether or not the left atrial ablation procedure has damaged the subject's esophagus before the subject experiences any symptoms of such damage. An esophageal monitoring device may also include sensors and/or markers that enable a determination of its location within a subject's esophagus. Such an esophageal monitoring device may be configured for three-dimensional mapping, and enable the generation of an accurate three-dimensional map of the physical relationship between a subject's esophagus and the left atrium of his or her heart. Methods of monitoring a subject's esophagus while a left atrial ablation procedure is being conducted on the subject's heart are also disclosed.

Abstract: A system that uses information from multiple players involved in an impact to improve the measurement of impact g-force by collaborative analysis and hence improve the prediction of the risk of concussion for an athlete, which includes a wearable device with an impact sensor and an application processor, and a smartphone mobile application. The wearable device is mounted to the player's helmet or other locations where the impact force to the head is measured. The wearable device wirelessly communicates with a smartphone, where the measured g-force, including magnitude and direction, from the wearable device, is obtained and an iterative optimization algorithm is run to make the correction and/or optimization of the measurement based on the law of physics. The said iterative optimization algorithm takes into the consideration of the data from all players involved in the impact, and minimize the error based on the law of physics.

Abstract: A controller in a computer-assisted teleoperated surgical system automatically moves a part of the system, in response to a user tapping the part, to facilitate draping of that part. This speeds the draping process and diminishes the likelihood that the sterile surgical drape is damaged or contaminated during the draping of that part of the system.

Abstract: A method for measuring the intraocular pressure (IOP) of an eye docked to an ophthalmic surgical laser system via a patient interface assembly. While the eye is docked to the laser system, and as the vertical force exerted on the eye by the patient interface fluctuates as the patient breaths and moves, the amount of corneal deformation is continuously measured by an optical coherence tomography device of the laser system and the force exerted on the eye is continuously measured by force sensors integrated in the patient interface assembly. Based on the real-time force signal and real-time corneal deformation signal, a controller calculates a linear relationship between force and corneal deformation, and determines the IOP of the docked eye by comparing a slope of the linear relationship against a pre-established slope vs. IOP calibration curve. The IOP of the docked eye can be used when setting laser treatment parameters.

Abstract: A health-monitoring method, system, and computer program product include operating at least one sensor of a health-monitoring device having a plurality of sensors, detecting a health condition event that requires operation of an additional sensor of the plurality of sensors to monitor the health condition event, activating the additional sensor of the health-monitoring device, and deactivating the additional sensor when the health condition event that requires the second sensor is no longer detected by the detecting.

Abstract: Methods for treating gastrointestinal conditions, conditions associated with sympathetic and/or parasympathetic activity in the gastrointestinal organs, and conditions associated with central sympathetic and/or parasympathetic activity in a patient with therapeutic gastrointestinalneuromodulation and associated systems and methods are disclosed herein. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves proximate a gastrointestinal artery of a gastrointestinal organ of a patient. Sympathetic drive in the patient can thereby be reduced in a manner that treats the patient for the gastrointestinal condition.

Abstract: The pumping of arterial blood into the cerebral spinal fluid (CSF) of a patient's brain creates cycle pressure undulations in the CSF and the brain itself. Brain injuries can create abnormal changes in this pressure waveform. Accordingly, the disclosed technology includes an ultrasound based device for monitoring this brain movement in the CSF (“pulsatility”) to diagnose and monitor brain injury.

Abstract: An electrocardiogram diagnostic system (30) having a non-athletic ECG diagnostic mode and an athletic ECG diagnostic mode. The electrocardiogram diagnostic system (30) employs an electrocardiogram wave controller (30) and an electrocardiogram diagnostic controller (50). In operation, the electrocardiogram wave controller (30) generates an ECG wave responsive to one or more electrode signals. In response thereto, the electrocardiogram diagnostic controller (50) classifies the ECG wave as either a non-athletic ECG wave or an athletic ECG wave, interprets a non-athletic classified ECG wave based on non-athletic ECG diagnostic criteria as either a normal non-athletic ECG wave or an abnormal non-athletic ECG wave, and interprets an athletic classified ECG wave based on athletic ECG diagnostic criteria as either a normal athletic ECG wave or an abnormal athletic ECG wave.

Abstract: A device for light-based skin treatment is provided. The device comprises a light source for providing an incident light beam for treating a skin, optical elements for focusing the incident light beam in a focal point inside the skin, and a skin interface element for, during use of the device, providing optical coupling of the incident light beam from the device into the skin. The skin interface element comprises a transparent exit window for allowing the incident light beam to leave the device, on top of the exit window, a transparent mixture of a polar substance and an apolar substance, and on top of the transparent mixture, a transparent foil, the transparent foil being more hydrophobic than the exit window.

Abstract: A stimulation device for activating at least one muscle involved in raising the foot while an individual is walking, comprising sensors which are to be placed on a lower limb of the individual, permitting calculation of a flexion angle of the knee; electrodes which are to be placed on the one or more muscles to be activated and able to electrically stimulate the one or more muscles, and a processing unit with computing means for calculating the value of the flexion angle of the knee on the basis of the measurement signals and for determining the oscillation phase in a walking cycle of the individual, and control means for the electrodes, the control means being designed to activate the electrodes only in the oscillation phase of a walking cycle of the individual, such that the electrodes generate an electrical stimulation with an intensity depending on the flexion angle of the knee, the intensity increasing as the flexion angle of the knee decreases, during the re-extension of the knee during the oscillation

Abstract: In an ophthalmic laser surgical system, a real-time optical coherence tomography (OCT) measurement method acquires OCT data during laser treatment. The treatment laser beam and OCT sample beam are generated simultaneously, and the optical delivery system scans them simultaneously in the eye tissue, where the focus of the treatment laser beam and the focus of the OCT beam coincide with each other in space. While both beams simultaneously scanned in the eye tissue, the OCT device detects returned OCT light from the sample during a data acquisition period, and generates an OCT A-scan based on the detected OCT light. Based on the A-scan, a controller determines a structure of the eye in a depth direction relative to the focus of the OCT beam, and controls the operations ophthalmic laser surgical system accordingly. One exemplary application is the formation of an arcuate corneal incision in cataract surgery.

Abstract: A method for treating a subject having a diseased or atrophic state of fibrotic tissue, kidney disease and associated nerve endings, or for promoting tissue regeneration in muscle tissue is accomplished through exposing the tissue with a laser light having a wavelength of about 400 nm to about 700 nm, or more preferably having a wavelength of about 405 nm, about 532 nm, about 635 nm, or a combination thereof. Subsequent to exposure, mesenchymal stem cells can be administered to the subject. After the administration of mesenchymal stem cells, the tissue is further exposed to laser light having a wavelength of about 400 nm to about 700 nm, or a laser light having a single wavelength of about 400 nm to about 700 nm. The mesenchymal cells can be interferon gamma activated.

Abstract: A photoplethysmographic (PPG) signal communicated by a PPG sensor of a wearable device worn by a user may be received by a processor. The processor may detect a plurality of heartbeats of the user from the PPG-signal, determine a heart rate of the user based on at least the plurality of heartbeats, determine a heart rate variability (HRV) based on the plurality of heartbeats, determine a respiration rate of the user based on a low frequency component of the PPG signal, and determine whether the user is in a stressed state based on the heart rate, the HRV, and the respiration rate. The processor may cause the display of information related to the stress state of the user, and instructions and/or advice for reducing a stress level of the user.

Abstract: An exemplary treatment system can be provided which can include a laser system configured to emit at least one laser beam, and an optical system configured to focus the laser beam(s) to a focal region at a selected distance from a surface of a tissue. The focal region can be configured to illuminate at least a portion of a target. The optical system can cause an irradiation energy transferred to the focal region of the laser beam(s) to (i) generate a plasma in a first region of the tissue adjacent to the target, and (ii) avoid a generation of a plasma in a second region of the tissue. The optical system has a numerical aperture that is in the range of about 0.5 to about 0.9. An exemplary method can also be provided to control such treatment system.

Abstract: Electrode array for monitoring of physiological parameters and devices including or utilizing same, the electrode array including an active electrode configured to provide an electrical signal and at least two inactive electrodes configured to collect the electrical signal transferred from the active electrode, wherein each of the at least two inactive electrodes are positioned at a different predetermined distance from the active electrode.

Abstract: The present disclosure provides apparatuses and methods for measuring capacitance as an indication of susceptibility to the formation of a diabetic foot ulcer.

Abstract: The disclosure relates to a pulsed laser system including a laser source that generates a laser beam, a scanner that controls the location of a beam focal point of the laser beam and also the location of a photodisruption formed at the beam focal point in a cornea of an eye, a computer that generates instructions to the laser source and scanner to direct the formation of a regular photodisruption pattern in the cornea, and a noise source that disturbs the location of each photodisruption to cause an irregular photodisruption pattern to form in the cornea, such that diffraction of light by the cornea after formation of the photodisruption pattern is decreased or avoided.

Abstract: The presently disclosed subject matter provides techniques for inducing collagen cross-linking in human tissue, such as cartilage or cornea, without using a photosensitizer (e.g., riboflavin), by inducing ionization of the water contained in the tissue to produce free radicals that induce chemical cross-linking in the human tissue. In an embodiment, a femtosecond laser operates at sufficiently low laser pulse energy to avoid optical breakdown of tissue. In an embodiment, the femtosecond laser operates in the infrared frequency range.

Abstract: A wearable for providing light therapy to a wearer includes at least one fabric panel having an inner surface that when the wearable is worn is configured to face a wearer's skin and an outer surface opposite the inner surface and at least one side-emitting optical fiber affixed to at least one of the inner surface and the outer surface. The side-emitting optical fiber is optically connectable with an optical fiber light source and configured to project light having a therapeutic wavelength toward a wearer of the wearable. The wearable can include at least one non-optical fiber light source affixed to the fabric panel so as to project light toward a wearer of the wearable. The non-optical fiber light source can have a respective side-emitting optical fiber of the at least one side-emitting optical fiber on opposite sides of the at respective non-optical fiber light source.

Abstract: The present disclosure provides, according to some embodiments, methods and systems for selectively reducing, blocking or inhibiting at least part of the neural activity in an organ of a subject. In preferred embodiments, the method and system are used for selectively blocking at least part of the neural activity in a duodenum of a subject in need thereof. According to some embodiments, the selective blocking occurs through use of laser radiation. According to some embodiments, the selective blocking comprises causing damage to at least part of sensory nerves located within a target area while maintaining functional activity of tissue surrounding the sensory nerves. According to some embodiments, the sensory nerves include neurons configured to transmit signals triggered by food passing through the duodenum, such as, but not limited to, neurohormonal signals.