Abstract: A pharmaceutical aerosol formulation comprising (a) a HFA propellant; (b) a pharmaceutically active polypeptide dispersible in the propellant; and (c) a surfactant which is a C8-C16 fatty acid or salt thereof, a bile salt, a phospholipid, or an alkyl saccharide, which surfactant enhances the systemic absorption of the polypeptide in the lower respiratory tract. The invention also relates to methods of manufacturing such formulations and the use of such formulations in treating patients.

Abstract: A composition which can be molded in the form of a stick or hot-poured, comprising at least one wax having a melting point of greater than 95° C. and a penetration of from 1 to 7.5 mm, and at least one organically modified beeswax having a penetration of greater than 7.5 mm, wherein the waxes are present in a combined amount sufficient to provide stability and a creamy texture to a molded stick or to a product resulting from hot-pouring, and a process for caring for and/or making-up the eyes, lips, or skin using this composition.

Abstract: Composition for topical administration comprising (a) a corticosteroid, and (b) a drying agent.

Abstract: A herbicidal composition for foliar treatment is described, which contains as active ingredients, (a) a compound of general formula [1] wherein R is alkyl, cycloalkyl, alkenyl, dimethylamino, or diethylamino; and (b) a compound selected from the group consisting of nicosulfuron, primisulfuron-methyl, rimsulfuron, halosulfuron-methyl, prosulfuron, thifensulfuron-methyl, chlorimuron-ethyl, or oxasulfuron. The herbicidal composition is useful for effective control of a wide variety of weeds in upland fields, particularly in corn fields and/or in soybean fields. Also described are a weeding method by foliar treatment of weeds with the above herbicidal composition; and use as a herbicide for foliar treatment, of a mixture of the above active ingredients.

Abstract: Parboiled rice flour is used in lieu of other grain flour in medical foods to minimize antigenicity of the medical food product.

Abstract: The invention relates to a microbial method of in vitro transformation of a steroid into its corresponding 11.alpha.-hydroxy analogue using oxygen and a microorganism selected from the Aspergillus ochraceus, Aspergillus niger, Rhizopus stolonifer, Rhizopus nigricans, Rhizopus arrhizus, and strains of Pestelotia, using as substrate a steroid having a purity of less than 97% and more than 90% at a concentration greater than 10 g/l.

Abstract: Fluorinated analogs of 1.alpha.,25-dihydroxyvitamin D.sub.3. These analogs are synthesized in a convergent manner by joining A-ring and C,D-ring fragments. Each hybrid analog, having a calcemia-lowering 1-hydroxymethyl group and a potentiating 16-ene-24,24-difluorinated C,D-ring and side chain, is designed to be lipophilic and inert toward 24-hydroxylase enzyme catabolism. Each hybrid analog with 1.beta.,3.alpha.-substituent stereochemistry shows a pharmacologically desirable combination of high antiproliferative and high transcriptional activities in vitro and also low calcemic activity in vivo.

Abstract: The present invention relates to a process for the preparation of a compound of the following structure: ##STR1## wherein, substituents are as defined in the specification.

Abstract: This invention is concerned with a novel anti-impotence composition and a novel method for the treatment of impotence, whereby deacetyl moxisylyte or one of its non-toxic salts is administered in a ready to use aqueous solution by injection per intracavernosal route, as a drug inducing a substantially rigid penile erection.

Abstract: A patterned image including on a substrate, a patterned image of a first resist polymeric material and patterned image of a second and different resist material on the first resist polymeric material. The polymeric material contains reactive hydrogen functional groups and/or reactive hydrogen precursor groups. At least the surface layer of the delineated and uncovered first resist polymer material is reacted with a multifunctional organometallic material containing at least two functional groups that are reactive with the functional groups of the polymeric material.