Patents Examined by Jose J. Dees
  • Ketamine analogues for treatment of thrombocytopenia
    Patent number: 5250732
    Abstract: 5,6-Dehydronorketamine and derivatives retaining the .alpha.,.beta.-unsaturated carbonyl are disclosed. These and other Michael or Michael-type acceptors and adducts are shown to influence the replication, differentiation or maturation of blood cells, especially platelet progenitor cells. Accordingly, these compounds are used for treatment of thrombocytopenia.
    Type: Grant
    Filed: July 18, 1991
    Date of Patent: October 5, 1993
    Assignee: Genentech, Inc.
    Inventors: Timothy P. Kogan, Todd C. Somers