Abstract: This disclosure is directed to a method for scoring and ranking candidate HLA-compatible unrelated hematopoietic cell donors (URD) for patients with AML or myelodysplastic syndrome. Candidate donors are scored based on KIR/HLA allele and genotype combinations. The method disclosed herein permits ranking and selection of advantageous donors that predict improved clinical outcomes of hematopoietic stem cell transplantation.

Abstract: The present invention is directed to a platform (e.g., Web-based) that enables basic and clinical research activities by integrating patient characteristics and clinical outcome data with a variety of high-throughput research data in a unified environment. While several rich data repositories for high dimensional research data exist in the public domain, most focus on a single data type and do not support integration across multiple technologies. The present invention in at least one embodiment includes a broad collection of bioinformatics and systems biology tools for analysis and visualization of four major “omics” types: DNA, mRNA, microRNA, and metabolites, as well as next-generation sequencing. The present invention helps facilitate systems medicine by providing easy identification of trends and patterns in integrated datasets and hence facilitate the use of better targeted therapies for cancer.

Abstract: A programmed computer system receives an imaging study of the patient including metadata associated with the study. The metadata are analyzed to determine an anatomic region represented by the study. Additional imaging studies for the same patient are requested and the metadata associated with the additional studies are analyzed to determine relevant studies for the same or adjacent anatomic regions. Once the relevant prior studies have been identified, the computer requests the images associated with the identified prior imaging studies including the associated reports for review by a physician or other medical personnel.

Abstract: A system and method for automatically calculating an accurate recommended dosage for hormone replacement therapy and automating the life cycle of a patient's treatment over time. The system and method can automatically acquire relevant patient parameters and apply a consistent formulaic approach to help reduce incorrect dosage determinations. A pellet insertion size may be determined and documented based on a calculated dosage, and an insertion side and lot numbers may be tracked and managed. In addition, corresponding revenues may be tracked and profitability may be reported for hormone replacement therapy practices.

Abstract: Healthcare costs accumulated across a plurality of claims systems are managed using a centralized accumulator, which receives cost accumulator data for adjudicated claims from multiple sending claim systems. An accumulator record type is identified from the cost accumulator data and used to generate a cross-reference record. The record type includes an adjudicated claim. A routing message is generated for at least one receiving claim system according to the identified accumulator record type, the cost accumulator data received from the sending claim system, and an identity of the at least one receiving claim system. In response to sending the routing message to the receiving claim system, an acknowledgement is received, which is used to update the cross-reference record by the processor.

Abstract: A system and method of confirming administration of medication in a clinical trial is provided. The method comprises the steps of receiving information identifying a particular medication prescription regimen in accordance with the clinical trial, determining one or more procedures for administering such prescription regimen and identifying one or more activity sequences associated with such procedures. Activity sequences of actual administration of such prescription regimen are captured and then compared to the identified activity sequences to determine differences therebetween. A notice is provided if differences are determined.

Abstract: Systems, methods, and computer-readable media for managing healthcare environments are provided. In embodiments, a real-time status of a clinical device, along with a location, is received. The location of the clinical device is obtained via a clinical device identifier that is tracked by a plurality of sensors in a healthcare environment. A clinical device may be identified as inappropriate for use and an alert presented to a clinician including the problem of the clinical device and the location thereof. A replacement clinical device may be located, using clinical identifiers, and presented to the clinician. Such monitoring and location awareness facilitates efficient responses to healthcare situations.

Abstract: Electronic health records of a plurality of patients are received. A risk prediction model for a disease based on the electronic health records of the plurality of patients is created. An electronic health record of an original patient is received. A neighboring group of patients of the plurality of patients is identified, wherein the neighboring group of patients is two or more patients similar to the original patient. An ordering of the two or more patients of the neighboring group of patients is received, wherein the ordering of the two or more patients of the neighboring group of patients is based upon how similar each patient of the two or more patients is to the original patient. The risk prediction model is updated based on the ordering of the two or more patients of the neighboring group of patients.

Abstract: A system for facilitating the provision of health care services to patients comprises a computer-readable medium containing information associated with the provision of health care services to patients; an electronic display disposed in a health care environment; and software configured to effect display of some of the information on the electronic display. A method for facilitating the provision of health care services to patients comprises inputting, via an electronic touch screen display, information corresponding to a patient or room; displaying, via the electronic touch screen display, the information; and providing, to a patient, physical health care services, based on the viewed information. The electronic touchscreen display preferably is not a part of a computer workstation and is configured for simultaneous viewing by a plurality of health care providers and caregivers.

Abstract: A decision-support system for medical diagnosis and treatment comprises software modules embodied on a computer readable medium, and the software modules comprise an input/output module and a question-answering module. The method receives patient case information using the input/output module, and generates a medical diagnosis or treatment query based on the patient case information and also generates a plurality of medical diagnosis or treatment answers for the query using the question-answering module. The method also calculates numerical values for multiple medical evidence dimensions from medical evidence sources for each of the answers using the question-answering module and also calculates a corresponding confidence value for each of the answers based on the numerical value of each evidence dimension using the question-answering module.

Abstract: Techniques for routing event data from a field device, such as an external defibrillator, to a selected subset of a plurality of possible destinations are described. The event data may include physiological data of the patient, such as a 12-lead electrocardiogram (ECG). The destinations may be associated with one of a plurality of patient treatment centers, and may include, as examples, computing device, printers, displays, personal digital assistants, or web-accessible accounts. In some examples, a server maintains user-configurable information or rules for at least some of the destinations, and uses the information or rules for determining whether event data received from a field device is routed to the destination. In some examples, the server may also make the routing determination based on an analysis of event data, such as a determination as to whether the event data indicates that the patient is suspected to be experiencing an acute myocardial infarction.

Abstract: A system and method for use in managing and preparing for scheduled procedures that are characterized as being interdependent and variable. The disclosed method enables schedule risk management and provides a look-ahead capability along with process diagnostics to isolate specific assets and tasks that can be managed to reduce schedule risk. The method facilitates review of upcoming tasks by the process stakeholders for education as to where the schedule risks reside and in an emulation mode for review and improved scheduling going forward. Clinical workflow is integrated such that process stakeholders and assets are directed in such a way as to keep on, reduce delay risk or recover the schedule.

Abstract: The present invention is directed to a system and method which allows a prospective insured to make an informed decision on healthcare insurance or a specific health care management decision by using a current medical profile to assist in their selection. Based on past medical care, as obtained from payor data, a number of different plans, each having different providers, different deductibles, different maximums, different reimbursement policies, etc., a person can make an informed decision. When a family has different payors for different family members, a proper blend of payors can be more easily selected since the payors (or a single payor) has a medical profile of each family member and also has information on providers in the network, prescription policies, deductibles, maximums, etc.

Abstract: In some embodiments, a social media communication may be obtained from a social media platform. The social media communication may include an anonymized version of a health care event information item associated with an event pertaining to an individual such that the anonymized version of the health care event information item refers to but does not specifically identify the event. The anonymized version may include a hash value of the social media communication in lieu of at least part of the health care event information. A link (including the hash value as a parameter related to a service request) may be generated based on the hash value of the social media communication. The service request may be provided to a service provider based on the link that comprises the hash value of the social media communication.

Abstract: Data mining of a dental image is described. In an example scenario, an aggregator service receives a dental image of a patient from a dental image provider. The dental image is processed with a machine learning (ML) anatomy dataset. An anatomy from the ML anatomy dataset is identified and matched to the dental image. The dental image is next matched and identified with a ML pathology and treatment dataset. A pathology and a treatment from the ML pathology and treatment dataset are matched to the dental image. Next, the dental image and the anatomy, the pathology, and the treatment associated with the dental image are inserted to a patient dataset associated with the patient. A cluster analysis of the patient dataset is performed with a cluster dataset to produce a correlated dental image information. The correlated dental image information is provided to a data mining entity and to compile a diagnostic aid for a user.

Abstract: A handheld personal communication apparatus for dialysis includes: a reader to (i) read a marking displayed on a dialysis fluid container to acquire data concerning at least one of a dialysis fluid type or a dialysis fluid volume from the marking, and/or (ii) receive a patient weight signal from a weight scale; a processor using at least one of the dialysis fluid type, dialysis fluid volume, or patient weight to determine a dialysis dwell time for at least one cycle of a dialysis therapy, the dialysis dwell time being a time to achieve, over the at least one cycle, at least one of (a) a specified ultrafiltrate level, (b) a urea removal level, or (c) a creatinine removal level; and an output interface providing an indication to the patient of a completion of the dialysis dwell time.

Abstract: A computer-implemented electronic messaging method and system, the method comprising the steps of receiving an electronic message at a first system, the electronic message comprising a healthcare provider type, obtaining contextual information associated with the electronic message at the first system, using the healthcare provider type and the contextual information to identify an intended recipient address for an intended healthcare provider recipient for the electronic message and providing the intended recipient address to facilitate delivery of the electronic message to the intended healthcare provider recipient.

Abstract: A method, system and computerized medium in a computerized environment for placing optional orders for an order set for a patient is provided. A request to display an order set for a patient is received. The order set comprises one or more optional orders. The optional orders that may or may not be placed for the order set. The optional orders are determined and the optional orders are displayed. A selection of one or more of the optional orders to be placed for the order set is received and the selected optional orders are placed for the order set.

Abstract: A system, method, and computer-readable media are provided for facilitating clinical decision making, and in particular, facilitating treatment of a person having congestive heart failure. The method includes the step of receiving patient information for a patient. The method also includes the steps of determining whether the patient information suggests a trigger event, and upon determining a trigger event, determining at least one goal associated with the trigger event. The method also includes the steps of selecting a first plan, from a library of plans, corresponding to the goal and executing the plan, which further includes determining a solver to determine patient conditions or recommended treatments, receiving parameters for the determined solver, and preparing patient information for the determined solver.

Abstract: One aspect of this disclosure is directed to methods, apparatuses, and systems for filtering medical findings. Another aspect of this disclosure is directed to methods, apparatuses, and systems for displaying filtered medical findings. Yet another aspect of this disclosure is directed to methods, apparatuses, and systems for generating user interfaces for setting parameters for filtering medical findings. Another aspect of this disclosure is directed to methods, apparatuses, and systems for displaying medical findings that passed through a filter. Other aspect of this disclosure is directed to methods, apparatuses, and systems for filtering and displaying medical information related to medical findings.