Abstract: Physiological monitoring can be provided through a lightweight wearable monitor that includes two components, a flexible extended wear electrode patch and a reusable monitor recorder that removably snaps into a receptacle on the electrode patch. The wearable monitor sits centrally on the patient's chest along the sternum oriented top-to-bottom. The placement of the wearable monitor in a location at the sternal midline, with its unique narrow “hourglass”-like shape, significantly improves the ability of the wearable monitor to cutaneously sense cardiac electrical potential signals, particularly the P-wave and the QRS interval signals indicating ventricular activity in the ECG waveforms. In particular, the ECG electrodes on the electrode patch are tailored to be positioned axially along the midline of the sternum for capturing action potential propagation in an orientation that corresponds to the aVF lead used in a conventional 12-lead ECG that is used to sense positive or upright P-waves.

Abstract: A device, system and method for temperature-based lesion formation assessment and mapping functionality using an accessory usable with an over-the-wire balloon catheter. The device may include a first annular element, a plurality of wires coupled to the first annular element, and a second annular element, the plurality of wires passing from the first annular element through the second annular element and into an elongate wire conduit coupled to the second annular element. At least one of the plurality of wires may include at least one temperature sensor and/or at least one mapping electrode. The first annular element coupled to an outer surface of a sheath. As a balloon catheter is advanced out of the sheath lumen, the distal tip of the catheter engages the second annular element and pushes the wires out of the sheath lumen, everting them over the balloon of the catheter.

Abstract: An electrode assembly for use with an electrosurgical instrument includes a base portion, a return lead adapted to be electrically coupled to a return terminal of an electrosurgical generator, an electrical insulator supported on a distal portion of the return lead, a tensioning mechanism, and an active lead adapted to be electrically coupled to an active terminal of the electrosurgical generator. The tensioning mechanism includes a slider slidably disposed in the base portion, a rotation rod threadably coupled to the slider, and a spring proximally biasing the slider. The active lead having a first end portion securely fixed to the base portion and a second end portion slidably coupled to the rotation rod of the tensioning mechanism. A portion of the active lead extends around the electrical insulator. Rotation of the rotation rod causes axial displacement of the second end portion of the active lead to tension the active lead about the electrical insulator.

Abstract: Disclosed are an adhesive transparent electrode and a method of fabricating the same. More particularly, an adhesive transparent electrode according to an embodiment of the present disclosure includes a substrate and an adhesive silicone-based polymer matrix, in which a metal nanowire network is embedded, deposited on the substrate, wherein the adhesive silicone-based polymer matrix includes a silicone-based polymer including a silicone-based polymer base and a silicone-based polymer crosslinker; and a non-ionic surfactant.

Abstract: A method of improving brain function in a hypothermic patient is provided. The method comprises administering to the patient an amount of a fibroblast growth factor 21 (FGF21) effective to increase RNA binding motif 3 (RBM3) production in nerve cells of the patient. The method is useful, for example, where the patient is or will be undergoing cardiac surgery or spinal surgery, such as requiring deep hypothermia circulatory arrest (DHCA), or is subject to an emergency preservation and resuscitation (EPR) method, or where a patient suffers from mild/moderate/severe traumatic brain injury (TBI), ventricular fibrillation cardiac arrest (VFCA), subarachnoid hemorrhage (SAH), subdural hematoma (SH), cerebral vasospasm, neonatal abusive head trauma (a.k.a. shaken baby syndrome), neonatal hypoxic ischemic encephalopathy (HIE), asphyxia cardiac arrest (ACA), treatment of spinal injury, prophylaxis in spinal surgery, stroke, and drug overdose.

Abstract: The present invention relates to a physiological monitoring device. Some embodiments of the invention allow for long-term monitoring of physiological signals. Further embodiments may also allow for the monitoring of secondary signals such as motion.

Abstract: It is recognized that, because of its unique properties, graphene can serve as an interface with biological cells that communicate by an electrical impulse, or action potential. Responding to a sensed signal can be accomplished by coupling a graphene sensor to a low power digital electronic switch that is activatable by the sensed low power electrical signals. It is further recognized that low power devices such as tunneling diodes and TFETs are suitable for use in such biological applications in conjunction with graphene sensors. While tunneling diodes can be used in diagnostic applications, TFETs, which are three-terminal devices, further permit controlling the voltage on one cell according to signals received by other cells. Thus, by the use of a biological sensor system that includes graphene nanowire sensors coupled to a TFET, charge can be redistributed among different biological cells, potentially with therapeutic effects.

Abstract: Devices, systems, and methods herein relate to cooling a head of a patient. These systems and methods may comprise a cooling cap assembly comprising a heat exchanger configured to be wrapped around a head of a patient and a compression assembly releasably coupled to the heat exchanger. The compression assembly may comprise an enclosure and an inflatable member coupled to an internal surface of the enclosure. When coupled, the inflatable member may be positioned between the enclosure and the heat exchanger. The heat exchanger may be separate from and moveable relative to the inflatable member.

Abstract: In methods for treating a patient, a time varying magnetic field is applied to a patient's body and causes a muscle contraction. The time-varying magnetic field may be monophasic, biphasic, polyphasic and/or static. The method may reduce adipose tissue, improve metabolism, blood and/or lymph circulation. The method may use combinations of treatments to enhance the visual appearance of the patient.

Abstract: A brainwave signal collecting device includes a main part and an elastic sleeve having a first opening. The main part is installed on the elastic sleeve, and the elastic sleeve can be positioned by suction on a user's head through the first opening after being pressed. The main part is in contact with the head to collect brainwave signals. The brainwave signal collecting device has an elastic sleeve serving as a flexible piece. When the brainwave signal collecting device is worn, the elastic sleeve can be pressed to partly exhaust the air therein so as to be positioned by suction on the head by the first opening of the elastic sleeve, which can improve the comfort of the head in contact with the elastic sleeve; and the position and angle at which the main part contacts the head can be adjusted through the deformation of the elastic sleeve.

Abstract: Example headsets and electrodes are described herein. Example electrode units described herein include a housing having a cavity defined by an opening in a side of the housing and an electrode. In some such examples, the electrode includes a ring disposed in the opening and an arm, where the arm has a first portion extending outward from the opening away from the housing and a second portion extending from an end of the first portion toward the housing and into the cavity, and the first and second portions connect at a bend.

Abstract: An electrosurgical forceps includes first and second shaft members pivotably coupled to one another such that pivoting of the first and second shaft members between spaced-apart and approximated positions pivots jaw members thereof between open and closed positions. A proximal end portion of the second shaft member may be pivoted against a resilient bias of a spring element to apply a predetermined clamping pressure on tissue and ultimately engage an activation switch to delivery electrosurgical energy to the clamped tissue.

Abstract: A medical electrode array system comprising a thin-film substrate, a plurality of electrode contacts disposed on the thin-film substrate, and a plurality of traces. The plurality of electrode contacts is configured to provide electrical contact points. The plurality of traces is electrically connected to the plurality of electrode contacts. A electrode contact of the plurality of electrode contacts has a dedicated trace of the plurality of traces that provides electrical connectivity to the electrode contact. The thin-film substrate is configured to flex to maintain continuous contact with contours of patient anatomy. The plurality of traces includes flexible spring-like portions to add flexibility to the thin-film substrate.

Abstract: A temperature modulation assembly and a multi-layer retention mechanism for such a temperature therapy device are disclosed. According to one embodiment, a temperature modulation assembly for a temperature therapy device has a heat spreader and a mounting plate coupled to a bottom portion of a spacer, wherein the heat spreader is disposed between the mounting plate and the spacer. The temperature modulation assembly has a heatsink and a fan coupled to a top portion of the spacer, wherein the heatsink is disposed between the top portion of the spacer and the fan. The temperature modulation assembly further includes a heating and/or cooling device disposed within a central opening of the spacer, wherein the heating and/or cooling device is located between the heatsink and the heat spreader.

Abstract: The present disclosure generally relates to intelligent garments that provide thermal regulation in a variety of environments. The garments may include different layers such as a hydrophobic layer in direct contact with a wearer's skin surface and saturated with an aqueous mixture, a spacer layer, a reflective layer, and an outer hydrophobic layer. The layers of the garment may work together to reduce the metabolic expenditure of the wearer in extreme environmental conditions or during demanding physical activity. A variety of sensors may be displaced throughout the garments so as to enable the collection of data associated with wearers as well as environmental conditions. Wearers may control the thermal balance and other properties of the garments as desired.

Abstract: An electroencephalography (EEG) headset can include an arrangement of straps that provides the ability to adjust the size and shape of the headset once disposed on a user's head. In some implementations, the headset can include a first elastic strap extending from a first side of the headset to a second side of the headset along a topside of the headset. The headset can also include a second strap including at least one inelastic portion and at least one elastic portion, at least one EEG electrode coupled to the second strap, a third elastic strap extending from the first side of the headset to the second side of the headset along an underside of the headset, and a plurality of connectors that couple the elastic first strap, the second strap, or the third elastic strap.

Abstract: A temperature controllable wrap assembly that includes a wrap portion configured to be worn around a user's body part, and at least a first temperature control module positioned on the wrap portion. The first temperature control module includes a housing, a controllable temperature element, a spreader member and at least a first finger spreader pivotably attached to the spreader member. The lower surface of the spreader member is positioned to contact the user's body part. The controllable temperature element is configured to transfer thermal energy to an upper surface of the spreader member, and the spreader member is configured to conduct thermal energy to the first finger spreader.

Abstract: An applicator has a stem, one or more tips, and one or more chambers which may hold therapeutic or medicinal fluids. The applicator may be separated into two sections so the tips can be used independently. The fluids held in the chambers may be separated with one or more frangible walls which can be broken to release or mix the fluids. The tips are used as applicators for the therapeutic or medicinal effects produced by the fluids or the medicines contained in the cavity.

Abstract: An intravenous heat exchange catheter and/or an external cooling pad/bladder can be used to maintain hypothermia in, e.g., a cardiac arrest patient, but to accelerate the cooling process the patient first can be infused with cold saline before the opportunity arises to connect the catheter or pad to the patient.

Abstract: A surgical device includes a handle assembly, an elongated portion, an end effector, a visualization device, and a constant horizon mechanism. The elongated portion extends distally from the handle assembly and defines a longitudinal axis. The end effector is rotatable about the longitudinal axis relative to the handle assembly. The visualization device defines a visualization axis. A first portion of the visualization device extends through the elongated portion, and a second portion of the visualization device is disposed at least partially within the handle assembly. The visualization device is rotatable about the longitudinal axis relative to the handle assembly. The constant horizon mechanism is disposed in operative engagement with the visualization device and is configured to prevent the visualization device from rotating about the visualization axis when the visualization device rotates about the longitudinal axis.