Patents Examined by Joseph Woitad
  • Modulating ramp activity
    Patent number: 6927317
    Abstract: The invention provides genetically-modified non-human mammals and genetically-modified animal cells containing a disrupted RAMP1, RAMP2, or RAMP3 gene. Also provided by the invention are methods of screening for agents that modulate the activity or expression of a RAMP and methods of treating mammals to modulate liver function and/or muscle metabolism.
    Type: Grant
    Filed: November 30, 2001
    Date of Patent: August 9, 2005
    Assignee: Pfizer, Inc.
    Inventors: John D. McNeish, Walter C. Soeller, John F. Thompson
  • Hepp, a novel gene with a role in hematopoietic and neural development
    Patent number: 6872812
    Abstract: The invention is directed to an isolated gene and protein product, designated Hepp, which has a role in mammalian hematopoiesis and neural function, and is further directed to a genetically modified non-human mammal that is homozygous or heterozygous for a disruption in the endogenous Hepp gene.
    Type: Grant
    Filed: February 15, 2002
    Date of Patent: March 29, 2005
    Assignee: University of Miami
    Inventors: Roland Jurecic, Ronald G. Nachtman
  • Transgenic mice comprising transcription control elements associated with mouse eosinophil peroxidase expression
    Patent number: 6858773
    Abstract: The present invention relates to novel transcription control elements derived from a mouse eosinophil peroxidase gene. The novel transcription control elements described in the disclosure may comprise isolated polynucleotides, expression cassettes, vectors, recombinant cells, and transgenic animals.
    Type: Grant
    Filed: April 19, 2002
    Date of Patent: February 22, 2005
    Assignee: Xenogen Corporation
    Inventors: Hongbing Zhang, Pamela Contag, Anthony Purchio, Amy Holt