Abstract: In certain embodiments, an ophthalmic surgical system for performing a surgical procedure on an eye comprises a laser device, a camera, and a computer. The laser device comprises a laser source and a scanner. The laser source generates a laser beam comprising pulses, and the scanner directs the pulses towards tissue of the eye according to a laser focal spot pattern. The camera captures surgical images of the eye. The computer instructs the laser device to direct the pulses towards the eye according to the laser focal spot pattern, accesses and monitor the surgical images of the eye, identifies an interfering object from the surgical images of the eye, and modifies the control of the pulses to compensate for the interfering object.

Abstract: A system for treating an eye includes a light source configured to provide photoactivating light that photoactivates a cross-linking agent applied to a cornea. The system includes one or more optical elements configured to receive the photoactivating light and produce a beam that defines a spot of the photoactivating light. The system includes a scanning system configured to receive the beam of the photoactivating light and to scan the spot of the photoactivating light along a first axis and a second axis to form a scan pattern on the cornea to generate cross-linking activity.

Abstract: Devices and methods of laser surgery of an eye, especially for refractive surgery, preferably for keratoplasty. The invention includes a planning and control unit, a system for laser surgery of an eye and a planning and control method wherein a device coordinate system of the first laser device and a device coordinate system of the characterization device are coupled using registration and measurement data or model data of the lamella can be unambiguously registered to the device coordinate systems, further by a defined edge geometry of the lamella, an ametropia correction during the generation of the lamella and by taking into account the hydration condition of the lamella, as well as methods for surgery.

Abstract: An illumination apparatus is disclosed, comprising: a first light source having a first spectral light distribution with a first light intensity peak about a first peak wavelength, and a second light source having a second spectral light distribution with a second light intensity peak about a second peak wavelength being different from the first peak wavelength, a third light source having a third spectral light distribution with a main light intensity peak about a third peak wavelength being different from the first peak wavelength and from the second peak wavelength, wherein the illumination apparatus is configured to provide adjustment of light intensity of the first light source and of light of the second light source, wherein the illumination apparatus provides an adjustment of light intensity of the third light source to compensate for the adjusting of the relative light intensity between the first light source and the second light source.

Abstract: A leadless biostimulator including an attachment feature to facilitate precise manipulation during delivery or retrieval is described. The attachment feature can be monolithically formed from a rigid material, and includes a base, a button, and a stem interconnecting the base to the button. The stem is a single post having a transverse profile extending around a central axis. The transverse profile can be annular and can surround the central axis. The leadless biostimulator includes a battery assembly having a cell can that includes an end boss. A tether recess in the end boss is axially aligned with a face port in the button to receive tethers of a delivery or retrieval system through an inner lumen of the stem. The attachment feature can be mounted on and welded to the cell can at a thickened transition region around the end boss. Other embodiments are also described and claimed.

Abstract: A computer implemented method for controlling a device adapted for projecting an image on at least a part of an eye of a wearer of said device, the method comprising the steps of providing the direction gaze of an eye of the wearer, providing an initial image to be projected, determining at least a filter depending from the provided gaze direction, filtering the initial image using the determined filter, and sending a command to the device for projecting the filtered image in the eye.

Abstract: Various embodiments provide a wellness tracking device with a base plate that may be utilized as a combination electrode by a variety of sensors. The base plate may be a multi-material electrode that includes a conductor and a transparent or semi-transparent material to enable optical sensing. In certain embodiments, the base plate supports a plurality of different sensors, which may selectively utilize the base plate as an electrode.

Abstract: An electrocardiogram device configured to transmit at least one signal responsive to a wearer's cardiac electrical activity can include a disposable portion and a reusable portion configured to mechanically and electrically mate with each other. The disposable portion can include a base having at least one mechanical connector portion, a plurality of cables and corresponding external ECG electrodes, and a first plurality of electrical connectors associated with the plurality of cables. The reusable portion can include a cover having at least one mechanical connector portion, a second plurality of electrical connectors configured to electrically connect with the first plurality of electrical connectors of the disposable portion, and an output connector port configured to transmit at least one signal responsive to one or more signals outputted by the external ECG electrodes of the disposable portion.

Abstract: A light therapy system (12) for administering a controllable melanopic luminous exposure includes a controllable lighting assembly (16) for use in delivering the desired luminous exposure. The system further includes a visual display means (18) for presenting at the same time a visual output such as a video to the patient. A target melanopic luminous exposure for administration to the patient is received by a controller 24. This target is then adjusted to compensate for an additional melanopic luminous exposure which the visual display means generates in displaying the visual output. A control schedule is then generated for controlling an illuminance of the lighting assembly to deliver over a defined treatment period the adjusted target melanopic luminous exposure. The lighting assembly is then controlled according to the control schedule.

Abstract: Systems and methods for pacing cardiac conductive tissue are described. An embodiment of a medical system includes an electrostimulation circuit to generate His-bundle pacing (HBP) pulses to stimulate a His bundle, and a cardiac event detector to detect a His-bundle activity within a time window following an atrial activity. The cardiac event detector may use a cross-chamber blanking, or an adjustable His-bundle sensing threshold, to avoid or reduce over-sensing of far-field atrial activity and inappropriate inhibition of HBP therapy. The electrostimulation circuit may deliver HBP in the presence of the His-bundle activity. The system may further recognize the detected His-bundle activity as either a FFPW or a valid inhibitory event, and deliver or withhold HBP therapy based on the recognition of the His-bundle activity.

Abstract: A system and method for modulating optogenetic vagus neurons in a noninvasive and transcutaneous manner is disclosed. The system and method comprises a two-dimensional array of organic light emitting diodes (OLEDs), a voltage-generating unit, a control unit, and a feedback loop. The array is placed on a subject's outer ear. Because the array is flexible, it can be closely placed on the skin of the outer ear. The array can deliver optical therapy and monitor heart rate variability (HRV) of the subject simultaneously, and the pixels of the array can be individually addressed. The voltage-generating unit generates pulsed voltage to the OLEDs. The control unit is connected to the array and controls the array and therapeutic patterns. The feedback loop uses the HRV to identify the therapeutic patterns.

Abstract: The present disclosure provides diagnostic methods for evaluating a urinary bladder and methods of enhancing the visibility of the bladder from outside of a patient. The method includes introducing urinary catheter having a proximal end and a distal end into a patient's urinary bladder by way of the urethra, the urinary catheter including an outer tubular member including an inflatable balloon disposed thereon, and a visualization stylet that is slidably disposable within a passage defined in the outer tubular member. The method further includes inflating the inflatable member inside of the bladder, inflating the bladder with a liquid to enhance visualization of an inner surface of the bladder, illuminating a light source through the inflatable member to illuminate the inner surface of the bladder, and visualizing an inner portion of the bladder using the visualization stylet.

Abstract: A wearable device is described. The wearable device may be constructed of one or more flexible materials, and may be referred to as a flexible wearable device. The flexible wearable device may include a flexible housing that is made of a material that is elastically deformable, where the flexible housing at least partially surrounds components of the flexible wearable device. The flexible housing may include apertures disposed within the surface of the flexible housing to enable light to be transmitted and received through the flexible housing. The flexible wearable device may also include a printed circuit board (PCB) disposed within the flexible housing (e.g., within a cavity formed by the flexible housing). The PCB may include sensors configured to acquire physiological data from a user by transmitting light and receiving light through the apertures. The PCB may be constructed of flexible regions that are elastically deformable.

Abstract: A lithotripsy apparatus includes: a treatment laser beam source that emits a treatment laser beam that crushes a stone; a guide light source that emits guide light; a photodetector that detects return light that returns as a result of the emitted guide light being reflected at the stone; and a processor including hardware, the processor being configured to: measure a distance from the treatment laser beam source to the stone on the basis of the return light; determine a condition of a bubble occurring between the treatment laser beam source and the stone on the basis of the measured distance; and adjust a light quantity of the treatment laser beam on the basis of the determined condition of the bubble.

Abstract: A robotic surgical system includes a surgical tool including a drive housing having first and second ends, a carriage movably mounted to the drive housing, and an elongate shaft extending from the carriage and penetrating the first end, the shaft having an end effector arranged at a distal end. An instrument driver is arranged at an end of a robotic arm and includes a body having proximal and distal ends and defining a central aperture extending between the proximal and distal ends, the shaft and the end effector penetrate the instrument driver by extending through the central aperture, an outer housing extending between the proximal and distal ends, a tool drive assembly provided at the proximal end and extending into the outer housing, and a drive motor operatively coupled to the tool drive assembly and operable to cause the tool drive assembly to rotate relative to the outer housing.

Abstract: A surgical instrument and method of operating same includes an end effector and a shaft assembly. The shaft assembly has proximal and distal shaft portions respectively extending along proximal and distal axes, a first elongate member, and an articulation section. The articulation section extends between the proximal and distal shaft portions and is configured to articulate about a first articulation axis and about a second articulation axis to thereby respectively deflect the end effector along a first plane and a second plane. The articulation section has a first lumen radially offset from the proximal and distal axes that longitudinally intersects the first and second articulation axes. The first lumen movably supports the first elongate member such that the radial spacing of the first elongate member is maintained relative to the proximal and distal axes at each of the first and second articulation axes during deflection of the end effector.

Abstract: Disclosed herein are various brain injury treatment systems, including various light delivery systems and devices. The various systems include a light delivery device that can be a headpiece or headgear having at least one light array disposed therein and a controller coupled to the at least one light array.

Abstract: A method is disclosed for determining a current position of an eye of a patient relative to an optical axis of a laser beam of a treatment apparatus. The method includes presetting a criterion characterizing the eye, determining a first target position of the eye relative to the optical axis, positioning a patient interface in a preset area in front of the optical axis, illuminating the eye during an approaching procedure of the patient interface to the eye, capturing a Purkinje image, which is associated with a cornea of the eye, by means of an optical capturing device during the approaching procedure, comparing the captured Purkinje image to the optical axis and determining the current position of the eye depending thereon, comparing the current position to the target position and with a deviation, outputting a control signal to a control device of the treatment apparatus.

Abstract: Methods and systems wherein laser induced refractive index changes by focused femtosecond laser pulses in optical polymeric materials or ocular tissues is performed to address various types of vision correction, and the laser induced changes to the refractive index avoid ablation and removal of the optical polymer materials while minimizing scattering losses.

Abstract: An implantable light generation arrangement for an optical or optical/electrical stimulation system includes a light source having an emission surface, wherein the light source is configured to generate light and emit the light from the emission surface; an optical waveguide having a first end and a core; a ball lens disposed between the light source and the optical waveguide and configured to receive the light emitted from the light source and direct the light onto the core at the first end of the optical waveguide; and a fixture holding the light source, optical waveguide, and ball lens in a fixed arrangement.