Abstract: Various embodiments provide a wellness tracking device with a base plate that may be utilized as a combination electrode by a variety of sensors. The base plate may be a multi-material electrode that includes a conductor and a transparent or semi-transparent material to enable optical sensing. In certain embodiments, the base plate supports a plurality of different sensors, which may selectively utilize the base plate as an electrode.

Abstract: An electrocardiogram device configured to transmit at least one signal responsive to a wearer's cardiac electrical activity can include a disposable portion and a reusable portion configured to mechanically and electrically mate with each other. The disposable portion can include a base having at least one mechanical connector portion, a plurality of cables and corresponding external ECG electrodes, and a first plurality of electrical connectors associated with the plurality of cables. The reusable portion can include a cover having at least one mechanical connector portion, a second plurality of electrical connectors configured to electrically connect with the first plurality of electrical connectors of the disposable portion, and an output connector port configured to transmit at least one signal responsive to one or more signals outputted by the external ECG electrodes of the disposable portion.

Abstract: A light therapy system (12) for administering a controllable melanopic luminous exposure includes a controllable lighting assembly (16) for use in delivering the desired luminous exposure. The system further includes a visual display means (18) for presenting at the same time a visual output such as a video to the patient. A target melanopic luminous exposure for administration to the patient is received by a controller 24. This target is then adjusted to compensate for an additional melanopic luminous exposure which the visual display means generates in displaying the visual output. A control schedule is then generated for controlling an illuminance of the lighting assembly to deliver over a defined treatment period the adjusted target melanopic luminous exposure. The lighting assembly is then controlled according to the control schedule.

Abstract: Systems and methods for pacing cardiac conductive tissue are described. An embodiment of a medical system includes an electrostimulation circuit to generate His-bundle pacing (HBP) pulses to stimulate a His bundle, and a cardiac event detector to detect a His-bundle activity within a time window following an atrial activity. The cardiac event detector may use a cross-chamber blanking, or an adjustable His-bundle sensing threshold, to avoid or reduce over-sensing of far-field atrial activity and inappropriate inhibition of HBP therapy. The electrostimulation circuit may deliver HBP in the presence of the His-bundle activity. The system may further recognize the detected His-bundle activity as either a FFPW or a valid inhibitory event, and deliver or withhold HBP therapy based on the recognition of the His-bundle activity.

Abstract: A system and method for modulating optogenetic vagus neurons in a noninvasive and transcutaneous manner is disclosed. The system and method comprises a two-dimensional array of organic light emitting diodes (OLEDs), a voltage-generating unit, a control unit, and a feedback loop. The array is placed on a subject's outer ear. Because the array is flexible, it can be closely placed on the skin of the outer ear. The array can deliver optical therapy and monitor heart rate variability (HRV) of the subject simultaneously, and the pixels of the array can be individually addressed. The voltage-generating unit generates pulsed voltage to the OLEDs. The control unit is connected to the array and controls the array and therapeutic patterns. The feedback loop uses the HRV to identify the therapeutic patterns.

Abstract: The present disclosure provides diagnostic methods for evaluating a urinary bladder and methods of enhancing the visibility of the bladder from outside of a patient. The method includes introducing urinary catheter having a proximal end and a distal end into a patient's urinary bladder by way of the urethra, the urinary catheter including an outer tubular member including an inflatable balloon disposed thereon, and a visualization stylet that is slidably disposable within a passage defined in the outer tubular member. The method further includes inflating the inflatable member inside of the bladder, inflating the bladder with a liquid to enhance visualization of an inner surface of the bladder, illuminating a light source through the inflatable member to illuminate the inner surface of the bladder, and visualizing an inner portion of the bladder using the visualization stylet.

Abstract: A wearable device is described. The wearable device may be constructed of one or more flexible materials, and may be referred to as a flexible wearable device. The flexible wearable device may include a flexible housing that is made of a material that is elastically deformable, where the flexible housing at least partially surrounds components of the flexible wearable device. The flexible housing may include apertures disposed within the surface of the flexible housing to enable light to be transmitted and received through the flexible housing. The flexible wearable device may also include a printed circuit board (PCB) disposed within the flexible housing (e.g., within a cavity formed by the flexible housing). The PCB may include sensors configured to acquire physiological data from a user by transmitting light and receiving light through the apertures. The PCB may be constructed of flexible regions that are elastically deformable.

Abstract: A lithotripsy apparatus includes: a treatment laser beam source that emits a treatment laser beam that crushes a stone; a guide light source that emits guide light; a photodetector that detects return light that returns as a result of the emitted guide light being reflected at the stone; and a processor including hardware, the processor being configured to: measure a distance from the treatment laser beam source to the stone on the basis of the return light; determine a condition of a bubble occurring between the treatment laser beam source and the stone on the basis of the measured distance; and adjust a light quantity of the treatment laser beam on the basis of the determined condition of the bubble.

Abstract: A robotic surgical system includes a surgical tool including a drive housing having first and second ends, a carriage movably mounted to the drive housing, and an elongate shaft extending from the carriage and penetrating the first end, the shaft having an end effector arranged at a distal end. An instrument driver is arranged at an end of a robotic arm and includes a body having proximal and distal ends and defining a central aperture extending between the proximal and distal ends, the shaft and the end effector penetrate the instrument driver by extending through the central aperture, an outer housing extending between the proximal and distal ends, a tool drive assembly provided at the proximal end and extending into the outer housing, and a drive motor operatively coupled to the tool drive assembly and operable to cause the tool drive assembly to rotate relative to the outer housing.

Abstract: Disclosed herein are various brain injury treatment systems, including various light delivery systems and devices. The various systems include a light delivery device that can be a headpiece or headgear having at least one light array disposed therein and a controller coupled to the at least one light array.

Abstract: A surgical instrument and method of operating same includes an end effector and a shaft assembly. The shaft assembly has proximal and distal shaft portions respectively extending along proximal and distal axes, a first elongate member, and an articulation section. The articulation section extends between the proximal and distal shaft portions and is configured to articulate about a first articulation axis and about a second articulation axis to thereby respectively deflect the end effector along a first plane and a second plane. The articulation section has a first lumen radially offset from the proximal and distal axes that longitudinally intersects the first and second articulation axes. The first lumen movably supports the first elongate member such that the radial spacing of the first elongate member is maintained relative to the proximal and distal axes at each of the first and second articulation axes during deflection of the end effector.

Abstract: A method is disclosed for determining a current position of an eye of a patient relative to an optical axis of a laser beam of a treatment apparatus. The method includes presetting a criterion characterizing the eye, determining a first target position of the eye relative to the optical axis, positioning a patient interface in a preset area in front of the optical axis, illuminating the eye during an approaching procedure of the patient interface to the eye, capturing a Purkinje image, which is associated with a cornea of the eye, by means of an optical capturing device during the approaching procedure, comparing the captured Purkinje image to the optical axis and determining the current position of the eye depending thereon, comparing the current position to the target position and with a deviation, outputting a control signal to a control device of the treatment apparatus.

Abstract: Methods and systems wherein laser induced refractive index changes by focused femtosecond laser pulses in optical polymeric materials or ocular tissues is performed to address various types of vision correction, and the laser induced changes to the refractive index avoid ablation and removal of the optical polymer materials while minimizing scattering losses.

Abstract: An implantable light generation arrangement for an optical or optical/electrical stimulation system includes a light source having an emission surface, wherein the light source is configured to generate light and emit the light from the emission surface; an optical waveguide having a first end and a core; a ball lens disposed between the light source and the optical waveguide and configured to receive the light emitted from the light source and direct the light onto the core at the first end of the optical waveguide; and a fixture holding the light source, optical waveguide, and ball lens in a fixed arrangement.

Abstract: A wearable electronic device is provided. The electronic device includes a plurality of electrodes configured to measure a biometric signal, an offset correction circuit, at least one processor operatively connected with the plurality of electrodes and the offset correction circuit, and a memory operatively connected with the at least one processor, wherein the memory stores instructions executed to enable the at least one processor to measure an offset between voltages via at least two electrodes among the plurality of electrodes and correct the offset via the offset correction circuit to allow the measured offset to fall within a threshold range.

Abstract: In some examples, a coil electrode assembly includes a coil electrode including a plurality of windings and extending from an electrode proximal end to an electrode distal end, the coil electrode defining an electrode lumen from the electrode proximal end to the electrode distal end. The coil electrode assembly further includes an insulative tube extending within the lumen of the coil electrode such that the coil electrode extends along an outer surface of the insulative tube. The coil electrode is partially embedded within the insulative tube when the insulative tube is in an expanded state to maintain a spacing between the windings.

Abstract: A method is disclosed for providing control data for an eye surgical laser of a treatment apparatus for the removal of a tissue. The method includes using a control device for determining a wavefront of a cornea and Zernike polynomials from the wavefront and calculating a respective tissue geometry for each Zernike polynomial. A combination of Zernike polynomials describes a tissue removal geometry. The control device ascertains a subgroup of the Zernike polynomials by an optimization calculation, which uses a preset condition to select Zernike polynomials. The condition is preset by a maximized target corneal geometry and a target imaging correction to be achieved. The target corneal geometry is a difference between a corneal geometry and the tissue removal geometry. An optimized tissue removal geometry is found using the subgroup and control data for controlling the eye surgical laser, which uses the optimized tissue removal geometry for separating the tissue.

Abstract: Embodiments of the present disclosure describe methods, systems, and computer storage media for detecting sepsis in a maternal patient and causing for display a visual indicator of a graphical object. In some aspects sepsis may be detected based on a maternal patient's patient information and/or clinical diagnostic. Technologies described herein may be used to determine maternal-fetal sepsis and provide a graphical object of a patient's risk of the maternal-fetal sepsis. The visual indicator and graphical object may be identifiable to a clinician as a warning of a risk for maternal-fetal sepsis. In this way, maternal-fetal sepsis may be identified and a graphical object may be generated, facilitating timely treatment and early diagnosis of maternal-fetal sepsis.

Abstract: A therapy, treatment and process for inactivating and/or killing COVID-19 (Corona Virus Disease 2019) is provided, including a low-dose, full body, Ultraviolet A1 (UV-A1, 360-400 nm) photon therapy, wherein the UV-A1 photon therapy activates singlet oxygen (1O2), which inactivates and/or kills COVID-19. UV-A1 therapy of the present invention can also be used to help alleviate symptoms and secondary illnesses caused by COVID-19. UV-A1 therapy of the present invention can also be used to help alleviate and treat pre-existing conditions of people that are also suffering from COVID-19 and worsened by COVID-19.

Abstract: A device includes an angiography module, a phototherapy module, a carrier including an optical filter and accommodating the angiography module and the phototherapy module, and a control unit controlling operation of the angiography module and the phototherapy module. The angiography module includes infrared LEDs emitting infrared light through the optical filter to irradiate a limb of a subject, and an infrared sensor sensing a part of the infrared light reflected off the limb to generate a result, based on which the control unit generates an angiogram. The phototherapy module emits infrared light through the optical filter to irradiate the limb for phototherapy.