Patents Examined by Joshua L Allen
  • Patent number: 10888863
    Abstract: This disclosure provides an apparatus and a method for quickly, efficiently and continuously fractionating biomolecules, such as DNAs and proteins based on size and other factors, while allowing imaging of the separated biomolecules as they are processed within the apparatus. The apparatus employs angled nanochannels to first preconcentrate and then separate like molecules. Its embodiments offer improved detection sensitivity and separation resolution over existing technologies and multiplexing capabilities.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: January 12, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Sung Hee Ko, Jongyoon Han
  • Patent number: 10876994
    Abstract: A sensor element includes an element body having an elongate rectangular parallelepiped shape and including solid electrolyte layers with oxygen ion conductivity, an outer pump electrode disposed on a first surface of the element body, and a protective layer covering at least a part of a second surface of the element body on a side opposite to the first surface and including one or more exposed spaces (a lower space) to which the second surface is exposed.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: December 29, 2020
    Assignee: NGK INSULATORS, LTD.
    Inventors: Takashi Hino, Mika Murakami, Koichi Masuda, Hironori Sakakibara
  • Patent number: 10866246
    Abstract: Devices and methods for characterization of samples are provided. Samples may comprise one or more analytes. Some methods described herein include performing enrichment steps on a device. Some methods described herein include performing mobilization of analytes. Analytes may then be further processed and characterized.
    Type: Grant
    Filed: February 4, 2020
    Date of Patent: December 15, 2020
    Assignee: INTABIO, INC.
    Inventors: Scott Mack, Erik Gentalen
  • Patent number: 10866206
    Abstract: A sensor element includes an element body having an elongate rectangular parallelepiped shape and including solid electrolyte layers with oxygen ion conductivity, an outer pump electrode disposed on a first surface of the element body, and a protective layer covering at least a part of the first surface of the element body and including one or more exposed spaces (an upper space) to which the first surface is exposed.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: December 15, 2020
    Assignee: NGK INSULATORS, LTD.
    Inventors: Takashi Hino, Mika Murakami, Koichi Masuda, Hironori Sakakibara
  • Patent number: 10852270
    Abstract: A sensor element includes an element body having an elongate rectangular parallelepiped shape and including solid electrolyte layers with oxygen ion conductivity, an outer pump electrode disposed on a first surface of the element body, and a protective layer covering at least a part of the first surface of the element body and including one or more spaces (an upper space) that are present apart from the first surface in a direction perpendicular to the first surface.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: December 1, 2020
    Assignee: NGK INSULATORS, LTD.
    Inventors: Takashi Hino, Mika Murakami, Koichi Masuda, Hironori Sakakibara
  • Patent number: 10807091
    Abstract: A method of driving an active matrix electro-wetting on dielectric (AM-EWOD) device comprises (i) setting a reference electrode to a first reference voltage; (ii) writing a set of data to array element electrodes of array elements of the device; and (iii) either (a) maintaining the voltages written to the array element electrodes until a time t0 or (b) re-writing the set of data N?1 times (where N?2). The reference electrode is then set to a second reference voltage different from the first reference voltage, and features (i) to (iii) are repeated. When the data are first written, there is a delay between the time when the voltage on the reference electrode is transitioned and the time when a given array element is next written with data.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: October 20, 2020
    Assignee: Sharp Life Science (EU) Limited
    Inventors: Benjamin James Hadwen, Jonathan Buse
  • Patent number: 10809227
    Abstract: A microcomputer calculates the concentration of ammonia contained in exhaust gas. The microcomputer repeatedly obtains from a first ammonia detection section a first ammonia electromotive force EMF1 whose value changes with both the concentrations of ammonia and a flammable gas contained in the exhaust gas. The microcomputer outputs, as ammonia concentration information at the present point in time, ammonia concentration information representing the ammonia concentration at the point 0.5 sec prior to the present point in time. The microcomputer sets a rich spike flag Fs when a first ammonia electromotive force change amount ?EMF1 is smaller than a value obtained by multiplying a start determination value by ?1. When the rich spike flag Fs is set, the microcomputer sets the ammonia concentration information at the present point in time to the value of the ammonia concentration information at the point immediately before the rich spike flag Fs is set.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: October 20, 2020
    Assignee: NGK Spark Plug Co., LTD.
    Inventors: Shinya Miyamoto, Yoshihiro Nakano
  • Patent number: 10775341
    Abstract: In a sensor element 101, oxygen contained in a gas to be measured introduced into a first internal space 20 through a first diffusion control part 11 is pumped out by applying voltage between an inner pump electrode 22 and an outer pump electrode 23. After the oxygen is pumped out, NOx in the gas to be measured generates oxygen by being reduced by a measurement electrode 44. This oxygen is pumped by applying voltage between the measurement electrode 44 and the outer pump electrode 23. On the basis of current generated according to the amount of oxygen thus pumped, the NOx gas concentration is calculated. A slit width of the first diffusion control part 11 on an entrance side is larger than a slit width on an exit side.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: September 15, 2020
    Assignee: NGK INSULATORS, LTD.
    Inventors: Akari Tominaga, Hirohito Kiyota
  • Patent number: 10775338
    Abstract: The invention relates to an electrochemical gas sensing apparatus for sensing one or more analytes, such as NO2 and/or O3, in a sample gas and a method of using same. The apparatus uses Mn2O3 as a filter for ozone. The Mn2O3 may take the form of a powder which may be unmixed, mixed with various PTFE particles sizes, formed into a solid layer deposited onto a membrane and/or pretreated with NO2.
    Type: Grant
    Filed: January 9, 2017
    Date of Patent: September 15, 2020
    Assignee: ALPHASENSE LIMITED
    Inventors: John Saffell, Ronan Baron, Marlene Hossain
  • Patent number: 10724986
    Abstract: A system, device and apparatus for measuring electrolytes, where an electrical charge is applied to a measurement portion to draw ions from a liquid to a gel-solution via at least one electric field. The gel-solution containing the extracted ions is excited with light of a predetermined wavelength from an emitter. A receiver detects the illumination of the ions as a result of the excited gel-solution, and a processor converts the detected intensities of the illumination to a biologically useful value representing ionic concentration.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: July 28, 2020
    Assignee: Indiana University Research & Technology Corporation
    Inventors: Afshin Izadian, Robert L. Bacallao
  • Patent number: 10718734
    Abstract: A method of determining an enhancement in rust-prevention of treated water by applying an electric current between a first cathode electrode and an anode electrode, and between a second cathode electrode and the anode electrode, wherein the first cathode electrode, the second cathode electrode, and the anode electrode are immersed in treated water; applying a comparative electric current between a first comparative cathode electrode and a comparative anode electrode, and between a second comparative cathode electrode and the comparative anode electrode, wherein the first comparative cathode electrode, the second comparative cathode electrode, and the at least one comparative anode electrode are immersed in untreated water; and determining an antirust effect of the treated water based on a first potential difference across the first cathode electrode and the second cathode electrode, and a second potential difference across the first comparative cathode electrode and the second comparative cathode electrode.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: July 21, 2020
    Assignee: Toshikogyo Co., Ltd.
    Inventors: Yasuo Tajiri, Mitsuo Ishikawa, Kunio Nemoto, Nobuyuki Kamiya
  • Patent number: 10712457
    Abstract: The invention relates to microfabrication technology for producing sensing cells, for use, for example, in molecular electronic transducer (MET) based seismometers devices. In some aspects, a method for fabricating a sensing element is provided. The method includes providing a first wafer including a first substrate, a second substrate, and a first insulating layer between therebetween, etching a first fluid throughhole through the first substrate, the first insulating layer, and the second substrate, and coating the first substrate and second substrate with a first and second conductive coating, respectively. The method also includes providing a second wafer including a third substrate, a fourth substrate, and a second insulating layer therebetween, etching a second fluid throughhole through the third substrate, the second insulating layer, and the fourth substrate, and coating the third substrate with a third conductive coating from top and the fourth substrate with a fourth conductive coating from back.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: July 14, 2020
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Hongyu Yu, Hai Huang
  • Patent number: 10663424
    Abstract: A sensor element includes a laminate, in which a plurality of oxygen ion-conductive solid electrolyte layers are stacked and in which a measurement object-gas flow portion is disposed, an inside pump electrode disposed on the inner circumferential surface of the measurement object-gas flow portion, an auxiliary pump electrode, and a measurement electrode. Then, the value of the volume ratio (Va=Vm/Vr) is 14.5 or more and 51.5 or less and the value of the volume ratio (Vb=Vs/Vr) is 5.0 or more and 17.5 or less, where the volume of the inside pump electrode 22 is specified as (Vm), the volume of the auxiliary pump electrode 51 is specified as (Vs), and the volume of the measurement electrode 44 is specified as (Vr).
    Type: Grant
    Filed: March 3, 2016
    Date of Patent: May 26, 2020
    Assignee: NGK INSULATORS, LTD.
    Inventors: Hironori Sakakibara, Shuichi Ozawa
  • Patent number: 10627365
    Abstract: A sensor control apparatus for a gas sensor which detects a particular gas component contained in a gas under measurement. In the case where humidity detection is performed using an electromotive-force-type gas sensor, a sensor control apparatus changes a target voltage of an electromotive force cell to a second target voltage for humidity detection and then to a third target voltage which is lower than a first target voltage which is a target voltage used for detecting the concentration of the particular gas component. In the case where humidity detection is performed using a limiting-current-type gas sensor, the sensor control apparatus changes the voltage applied to a pump cell to a second application voltage for humidity detection and then to a third application voltage which is lower than a first application voltage which is an application voltage used for detecting the concentration of the particular gas component.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: April 21, 2020
    Assignee: NGK SPARK PLUG CO., LTD.
    Inventors: Dai Nishijima, Satoshi Teramoto
  • Patent number: 10591488
    Abstract: Devices and methods for characterization of samples are provided. Samples may comprise one or more analytes. Some methods described herein include performing enrichment steps on a device. Some methods described herein include performing mobilization of analytes. Analytes may then be further processed and characterized.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: March 17, 2020
    Assignee: Intabio, Inc.
    Inventors: Erik Gentalen, Scott Mack
  • Patent number: 10551343
    Abstract: Provided is a method of inspecting an assembly defect of a gas sensor in a mass-production process. The sensor element included in a second constituting member includes a heater therein and an electrode terminal for a heater in its surface, and the first constituting member includes a contact point member contacting the terminal in a state where the sensor element is inserted into its opening. A first heater resistance value before incorporated is measured to associate the resistance value with an identification information of the sensor element, a second heater resistance value is measured via a contact point member, in a state where the first and second constituting members are integrated with each other, to associate the resistance value with the identification information of the sensor element, and when a difference value between these resistance values associated with the identical identification information exceeds a threshold value, it is determined that an assembly defect occurs.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: February 4, 2020
    Assignee: NGK INSULATORS, LTD.
    Inventors: Naoya Saito, Noriyuki Ina, Kazuki Takegawa
  • Patent number: 10509009
    Abstract: A sensor control apparatus for a gas sensor which detects a particular gas component contained in a gas under measurement. In the case where humidity detection is performed using an electromotive-force-type gas sensor, a sensor control apparatus changes a target voltage of an electromotive force cell to a second target voltage for humidity detection and then to a third target voltage which is lower than a first target voltage which is a target voltage used for detecting the concentration of the particular gas component. In the case where humidity detection is performed using a limiting-current-type gas sensor, the sensor control apparatus changes the voltage applied to a pump cell to a second application voltage for humidity detection and then to a third application voltage which is lower than a first application voltage which is an application voltage used for detecting the concentration of the particular gas component.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: December 17, 2019
    Assignee: NGK SPARK PLUG CO., LTD.
    Inventors: Dai Nishijima, Satoshi Teramoto
  • Patent number: 10487416
    Abstract: Electrochemical machining of parts employs electric or voltage pulses in which current flows in a first direction and a second direction opposite from the first direction. The cathodic/anodic pulses switch between bulk machining and oxide removal pushing bulk material removal into a homogenous regime to obtain a smooth surface finish and appropriate form control during the electrochemical machining process compared to electrochemical machining employing an electric or voltage potential in which current flows in only one direction.
    Type: Grant
    Filed: June 15, 2015
    Date of Patent: November 26, 2019
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Andrew Lee Trimmer, John Cottrill, Douglas Lewis
  • Patent number: 10451583
    Abstract: The gas sensor is equipped with a sensor device, a plurality of electrode springs contacting with electrodes and of the sensor device, an insulator retaining the electrode springs, and a plurality of leads connected to the respective electrode springs. Each of the electrode springs includes a retained portion retained by the insulator and a contact portion which is bent and inclined from the retained portion toward a front end side of the sensor device in the lengthwise direction. The contact portion is elastically deformed in contact with the electrode. Each of the electrode springs also includes a bent portion between the contact portion and the retained portion. The bent portion constitutes a base end of the contact portion and is oriented toward the base end side of the gas sensor in the lengthwise direction, thereby enabling the length of the sensor device to be decreased and improving the heat resistance of the electrode springs.
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: October 22, 2019
    Assignee: DENSO CORPORATION
    Inventors: Hirofumi Noda, Hirokazu Yamada
  • Patent number: 10451584
    Abstract: Provided is a biomolecule measuring device capable of effectively reducing measurement noise occurring when measuring a biomolecule sample using a semiconductor sensor. This biomolecule measuring device generates a trigger to react a sample with a reagent after starting to send the reagent onto the semiconductor sensor that detects ion concentration (see FIG. 7).
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: October 22, 2019
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Yoshimitsu Yanagawa, Takahide Yokoi, Naoshi Itabashi, Takayuki Kawahara, Sonoko Migitaka, Makiko Yoshida, Takamichi Muramatsu